http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19
Choudhary Sarita,Sreenivasulu Karli,Mitra Prasenjit,Misra Sanjeev,Sharma Praveen 대한진단검사의학회 2021 Annals of Laboratory Medicine Vol.41 No.2
Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a pandemic affecting nearly all countries worldwide. As the COVID-19 pandemic progresses, the need to identify genetic risk factors for susceptibility to this serious illness has emerged. Host genetic factors, along with other risk factors may help determine susceptibility to respiratory tract infections. It is hypothesized that the ACE2 gene, encoding angiotensin-converting enzyme 2 (ACE2), is a genetic risk factor for SARS-CoV-2 infection and is required by the virus to enter cells. Together with ACE2, transmembrane protease serine 2 (TMPRSS2) and dipeptidyl peptidase-4 (DPP4) also play an important role in disease severity. Evaluating the role of genetic variants in determining the direction of respiratory infections will help identify potential drug target candidates for further study in COVID-19 patients. We have summarized the latest reports demonstrating that ACE2 variants, their expression, and epigenetic factors may influence an individual’s susceptibility to SARS-CoV-2 infection and disease outcome.
Swati Chowdhury,Sudipta Roy,Anirban Mitra,Prasenjit Das 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.7
Image segmentation subdivided an image into its constituent regions or segments. This regions or segments of an image is known as ‘cluster’ and the method used for this is called ‘clustering method’. There are different methods or algorithms are out there to segment an image. There is a problem with those algorithms user has to supply the number of cluster in which it has to be segmented. Here we introduced a method using combination of both entropy of RGB color component and histogram to automatic determination of cluster present in a color image.