국내 주요 상수원수와 처리수에서 HAAs 생성 특성

염철민,최유식,변석종,조순행,윤제용 대한상하수도학회 2002 상하수도학회지 Vol.16 No.2

This study was conducted to investigate the haloacetic acid (HAAs) formation characteristics in raw and treated water in Korea. The raw and treated water from the five major rivers were examined to measure the HAAs concentrations and compared those with literature values. Major findings are as follows. First, average HAAs concentration of treated water (collected from three water treatment plants) in Korea appeared to be 62.5±66.7㎍/L (n=7) and this level is higher than the average trihalomethanes (THMs) concentration (13.2±12.9㎍/L, n=6933) reported recently. Second, the average formation potential of TCAA and DCAA after three days was found as 103±74㎍/L (n=14) and 76±36㎍/L (n=14), respectively. As this result was applied to US-EPA developed model equation for TCAA and DCAA formation, dissolved organic matter (DOM) in Korea has a tendency to produce more TCAA and DCAA as compared to US. This phenomenon was especially notable in DCAA. The sum of weight percentage of TCAA and DCAA which are individual component of HAAS was composed of 80% of HAAs.

관상동맥색전증에 의한 급성심근경색증 4예

김민근,주혜원,강경필,최병돈,박민석,변영섭,고충원,이건주,김병옥 인제대학교 2006 仁濟醫學 Vol.27 No.-

Acute myocardial infarction(AMI) due to coronary embolism can occur in patients with normal coronary artery. Coronary embolism is believed to be a cause of acute myocardial infarction when emergent coronary angiography shows perfectly normal coronary trees, except for the finding of coronary artery occlusion. In this report, we describe four patients with AMI due to coronary embolism who were successfully treated using a thrombus aspiration device and anticoagulation, and those patients had intracardial thrombus arising from the left atrium due to chronic atrial fibrillation and valvular heart disease. Patients with chronic or paroxysmal atrial fibrillation can present with AMI due to coronary embolism, and thrombus aspiration with percutaneous aspiration device is a feasible treatment option for these patients along with anticoagulation the rapy.

국내 상수원수의 유기물 특성에 따른 소독부산물 생성능

염철민,변석종,조순행,윤제용 대한상하수도학회 2003 상하수도학회지 Vol.17 No.1

This study was conducted to investigate the characteristics of disinfection by-products formation potential (DBPFPs) of dissolved organics. Dissolved organics in raw water were separated into two fractions ((1) hydrophilic and (2) hydrophobic) for the measurement of DBPs. Three types of DBPs (trihalomethanes (THMs), haloacetic acids (HAAs), and total organic halides (TOX)) were measured at 3days and 7days incubation time. Sample waters were collected from the Han River and the Wonchun Reservoir. Two major findings are as follows. First, THMFPs/DOC, HAAFPs/DOC and TOXFPs/DOC in the hydrophilic organic component had a level of lower value than those of the hydrophobic organic component. Brominated THMs and bominated HAAs were not found in the chlorinated hydrophobic organic component. Second, the magnitude of HAAFPs/DOC were higher than that of THMFPs/DOC in both hydrophilic and hydrophobic organic components. This results support the reported observation that HAAs formations were higher than that of THMs in chlorinated drinking water. THMFPs and HAAFPs comprised 53-91% of TOXFP.

무산소성 운동이 혈청 지질 농도 및 면역세포 반응에 미치는 영향

조영주,변재철,홍석민 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

The purpose of this study was to determine serum lipids and immune responses on the anaerobic exercise. Serum total cholesterol, HDL-C, LDL-C and plasma triglyceride, percentages of WBC and their subsets, natural killer cells were evaluated between before and after the anaerobic power. All subjects were high trained male athletes (19-24 years of age). Results were expressed as mean and standard deviations. One-way ANOVA repeated measure was used to compare the all parameters between before and after the anaerobic power test. All significant differences were set at α=.05. In this study, comparison of anaerobic power(Nm/%BW) was higher in soccer players than ssirum and judo players (p<.05). The percentage of WBC, monocyte, eosinophil and basophil were no significant differences between before and after anaerobic exercise. There were increased on neutrophil, lymphocyte after anaerobic exercise in three groups. (p<.01, p<.001, respectively). Also, there were significant differences on T cell, B cell, NK cell between before and after anaerobic exercise (p<.001).

中醫治驗例를 中心으로 살펴본 癌性 疼痛의 外治法

李潤熙,申珉圭,卞俊晳 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

Carcinous pain is severe and continuous so difficult to alleviate. Western drugs give rise to reation such as anoresia, constipation, voniting, general weakness and dyspnea, And they cause tolerence. External treatment is a way to put a patch or rub a liquid on the skin. The patch and liquid are made from herb medicine. In china, they have a good effect of alleviating carcinous pain to make use of external treatment. Usually they use the medicine with effect of reprecussion(消腫)removing obstruction(散結), activating blood flow and removing blood stasis (活血化瘀)such like Borneloum(水片). Bufonis Venenum (蟾?), Aconiti Ciliane Tubber(草鳥), Arisaematis Rhizoma(南星), Asari herba cum Radice (細辛)etc. We can get the alleviating effect more quickly and prevent reaction through extermal treatment.

난원공 개존을 통한 우심방에서 좌심방으로의 단락 진단에 있어 경흉부 심초음파 하모닉 영상의 유용성

신미승,강석민,장길진,변기현,하종원,정남식,허지회,이병인 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

담낭종양에서 CD24의 역할

임성철,이용,김동출,강길,변익건,박정희,최석민 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

CD24 is a small heavily glycosylated glycosylphosphatidylinosito-linked cell surface protein, which is expressed in hematologic malignancies as well as in a large variety of solid tumors, It appears to function as a ligand of PUselectin, an adhesion molecule that is present in activated platelets and endothelial cells. The authors aimed to evaluate CD24 protein expression in adenoma and adenocarcinoma of gallbladder to correlate to clinicopathologic data. The staining- was evaluated as stainability (negative, weak-, moderate-, strong-positive) and staining' patterns (membranous vs. intracytoplasmic) for statistical analysis. A highly significant association of cytoplasmic CD24 expression with adenocarcinoma compared to the adenoma of gallbladder was demonstrated. The present study demonstrates that CD24 was abundantly expressed on adenocarcinoma rather than on adenoma, but it was not statistically significant, Interrelation between the stainability or intracytoplasmic staining of CD24 and lymph node metastasis was not statistically significant. The authors conclude that CD24 is involved in tumorigenesis of gallbladder mucosa and intracytoplasmic expression of CD24 is an important molecular marker for malignant transformation.

An efficient simulation and analysis method of moiré patterns in display systems

Byun, Seok-Joo,Byun, Seok Yong,Lee, Jangkyo,Kim, Won Mok,Kim, Han-Pil,Jeon, Min Yong,Lee, Taek-Sung The Optical Society 2014 Optics express Vol.22 No.3

Decompressive Surgery in a Patient with Posttraumatic Syringomyelia

Byun, Min-Seok,Shin, Jun-Jae,Hwang, Yong-Soon,Park, Sang-Keun The Korean Neurosurgical Society 2010 Journal of Korean neurosurgical society Vol.47 No.3

Posttraumatic syringomyelia may result from a variety of inherent conditions and traumatic events, or from some combination of these. Many hypotheses have arisen to explain this complex disorder, but no consensus has emerged. A 28-year-old man presented with progressive lower extremity weakness, spasticity, and decreased sensation below the T4 dermatome five years after an initial trauma. Magnetic resonance imaging (MRI) revealed a large, multi-septate syrinx cavity extending from C5 to L1, with a retropulsed bony fragment of L2. We performed an L2 corpectomy, L1-L3 interbody fusion using a mesh cage and screw fixation, and a wide decompression and release of the ventral portion of the spinal cord with an operating microscope. The patient showed complete resolution of his neurological symptoms, including the bilateral leg weakness and dysesthesia. Postoperative MRI confirmed the collapse of the syrinx and restoration of subarachnoid cerebrospinal fluid (CSF) flow. These findings indicate a good correlation between syrinx collapse and symptomatic improvement. This case showed that syringomyelia may develop through obstruction of the subarachnoid CSF space by a bony fracture and kyphotic deformity. Ventral decompression of the obstructed subarachnoid space, with restoration of spinal alignment, effectively treated the spinal canal encroachment and post-traumatic syringomyelia.

Kv3.1 and Kv3.4, Are Involved in Cancer Cell Migration and Invasion

Song, Min Seok,Park, Su Min,Park, Jeong Seok,Byun, Jin Ho,Jin, Hee Jung,Seo, Seung Hyun,Ryu, Pan Dong,Lee, So Yeong MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.4

<P>Voltage-gated potassium (Kv) channels, including Kv3.1 and Kv3.4, are known as oxygen sensors, and their function in hypoxia has been well investigated. However, the relationship between Kv channels and tumor hypoxia has yet to be investigated. This study demonstrates that Kv3.1 and Kv3.4 are tumor hypoxia-related Kv channels involved in cancer cell migration and invasion. Kv3.1 and Kv3.4 protein expression in A549 and MDA-MB-231 cells increased in a cell density-dependent manner, and the pattern was similar to the expression patterns of hypoxia-inducible factor-1α (HIF-1α) and reactive oxygen species (ROS) according to cell density, whereas Kv3.3 protein expression did not change in A549 cells with an increase in cell density. The Kv3.1 and Kv3.4 blocker blood depressing substance (BDS) did not affect cell proliferation; instead, BDS inhibited cell migration and invasion. We found that BDS inhibited intracellular pH regulation and extracellular signal-regulated kinase (ERK) activation in A549 cells cultured at a high density, potentially resulting in BDS-induced inhibition of cell migration and invasion. Our data suggest that Kv3.1 and Kv3.4 might be new therapeutic targets for cancer metastasis.</P>