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김경택(Gyeong Taek Kim),이원준(Won June Lee),차민석(Min Suk Cha),박정(Jeong Park),정석호(Suk Ho Chung),권오붕(Oh Boong Kwon),김민국(Min Kuk Kim),이상민(Sang Min Lee) 한국연소학회 2016 한국연소학회지 Vol.21 No.3
The effect of applied electric fields on jet flow instability was investigated experimentally by varying the direct current (DC) voltage and the alternating current (AC) frequency and voltage applied to a jet nozzle. We aimed to elucidate the origin of the occurrence of twin-lifted jet flames in laminar jet flow configuration, which occur when AC electric fields are applied. The results indicate that a twin-lifted jet flames originates from cold jet instability, caused by interactions between negative ions in the jet flow via electron attachment as O₂ + e → O₂<SUP>-</SUP> when AC electric fields are applied. This was confirmed by experiments in which a variety of gaseous jets were ejected from a nozzle to which DC voltages and AC frequencies and voltages were applied, with ambient air between two deflection plates connected to a DC power source. Experiments in which jet flows of several gases were ejected from a nozzle and AC electric fields were applied in coflow-nitrogen provided further evidence. The flow instability occurred only for oxygen and air jets. Additionally, jet instability occurred when the applied frequency was less than 80 Hz, corresponding to the characteristic collision response time. The effect of AC electric fields on the overall structure of the jet flows is also reported. Based on these results, we propose a mechanism to reduce jet flow instability when AC electric fields are applied to the nozzle.
Cha Joon-Yung,Shin Gyeong-Im,Ahn Gyeongik,Jeong Song Yi,Ji Myung Geun,Alimzhan Aliya,Kim Min Gab,Kim Woe-Yeon 한국응용생명화학회 2022 Applied Biological Chemistry (Appl Biol Chem) Vol.65 No.5
Herbicides play a crucial role in maintaining crop productivity by reducing competition between weeds and crops. Protoporphyrinogen oxidase (PPO)-inhibiting herbicides trigger the photooxidative damage that destroys cell membranes. Tiafenacil is a recently developed pyrimidinedione-type PPO-inhibiting herbicide that has low IC50 values in plants and is less toxic in humans compared to other PPO inhibitors. Previous reports confirmed that mutations in Arabidopsis circadian clock-controlled gene GIGANTEA (GI) were insensitive to phytooxidants, including chloroplast biogenesis inhibitors and herbicides. Here, we examined whether GI regulates the resistance to tiafenacil. Both gi mutant alleles, gi-1 and gi-2, were resistant to tiafenacil with survival rates of 97% and 83%, respectively, under 1 μM tiafenacil treatments, while 56% of wild-type and GI-overexpressing plants (GI-OX) survived. Both gi mutants were insensitive to tiafenacil-induced inhibition of photosystem efficiency and alleviated photooxidative damage. The gi mutants showed significant increases in transcriptional expressions and enzyme activities of antioxidants compared to wild-type and GI-OX. Moreover, loss-of-function in GI enhanced resistance to tiafenacil-containing commercial herbicide Terrad’or Plus ®. Collectively, based on our results together with previous reports, mutations in GI confer resistance to herbicides with different MoAs and would be a crucial molecular target for non-target-site resistance strategies to develop herbicide-resistant crops.
( Gyeong Min Jeong ),( Hee Jeong Cha ),( Ji Hun Lim ),( Hawk Kim ),( Jae Cheol Jo ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Myeloproliferative neoplasm is associated with lymphoproliferative disease after cytotoxic drugs or radiation exposure, despite the rarity prior to therapy. Methods: We report a 61-year-old female patient with a history of transient ischemic attack who was simultaneously diagnosed as having follicular lymphoma and unclassi- fiable myeloproliferative neoplasm. Results: The patient complained of palpable mass on epitrochlear area of left arm, recently. Excisional lymph node biopsy revealed the follicular lymphoma (grade 1) with stage I. Laboratory findings showed leukocytosis (white blood cell 16040/μL), erythrocytosis (hemoglobin 17.5g/dL, hematocrit 58.3%), thrombocytosis (platelet 782000/ μL), decreased erythropoietin 6.26mU/mL. Bone marrow biopsy disclosed hypercellularity with predominance of erythroid series and big polylobated megakaryocytes with inceased mitotic figures, and no evidence of lymphomatous infiltration. JAK2 V617F mutation was detected in bone marrow specimen. After local excision of lymph node on left epitrochlear area, radiation is delivered to the involved field at a dose of 24 Gy in 12 fractions. She was started on hydroxyurea 1g bid orally, in 2 weeks passed after the end of the radiation therapy, and has been maintained with hydroxyurea 500mg bid. After 6 months of follow up, her WBC decreased to 7430/μL, hemoglobin to 12.2g/dL and platelet count decreased to 379000/μL and the patient keeps in good condition. A computerized tomography scan of the neck, chest and abdomen also were within normal limits. Conclusion: This is a first case report on follicular lymphoma coexisting with unclassi fiable myeloproliferative neoplasm in a previously healthy patient. On this extremely infrequent disease association, molecular and genetic studies warrant.