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RISS 인기검색어
- 검색키워드
- 저자 : Michael J. Rosen (검색결과 2 건)
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Endoscopic Diagnosis of Duodenal Stenosis in a 5-Month-Old Male Infant
Maribeth R. Nicholson,Sari A. Acra,Dai H. Chung,Michael J. Rosen 대한소화기내시경학회 2014 Clinical Endoscopy Vol.47 No.6
Duodenal stenosis and duodenal atresia are well-known gastrointestinal anomalies in patients with Down syndrome. Although duodenal atresia presents early and classically with vomiting in the immediate neonatal period, the presentation of duodenal stenosis can be significantly more subtle and the diagnosis delayed. Here, we describe the case of a 5-month-old male infant with Down syndrome and delayed presentation of high-grade duodenal stenosis diagnosed endoscopically. Pediatric gastroenterologists should include duodenal stenosis in the differential diagnosis of older infants and children with vomiting and should be familiar with the endoscopic appearance of this lesion.
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Centennial-scale changes in the global carbon cycle during the last deglaciation
Marcott, Shaun A.,Bauska, Thomas K.,Buizert, Christo,Steig, Eric J.,Rosen, Julia L.,Cuffey, Kurt M.,Fudge, T. J.,Severinghaus, Jeffery P.,Ahn, Jinho,Kalk, Michael L.,McConnell, Joseph R.,Sowers, Todd Nature Publishing Group, a division of Macmillan P 2014 Nature Vol.514 No.7524
Global climate and the concentration of atmospheric carbon dioxide (CO<SUB>2</SUB>) are correlated over recent glacial cycles. The combination of processes responsible for a rise in atmospheric CO<SUB>2</SUB> at the last glacial termination (23,000 to 9,000 years ago), however, remains uncertain. Establishing the timing and rate of CO<SUB>2</SUB> changes in the past provides critical insight into the mechanisms that influence the carbon cycle and helps put present and future anthropogenic emissions in context. Here we present CO<SUB>2</SUB> and methane (CH<SUB>4</SUB>) records of the last deglaciation from a new high-accumulation West Antarctic ice core with unprecedented temporal resolution and precise chronology. We show that although low-frequency CO<SUB>2</SUB> variations parallel changes in Antarctic temperature, abrupt CO<SUB>2</SUB> changes occur that have a clear relationship with abrupt climate changes in the Northern Hemisphere. A significant proportion of the direct radiative forcing associated with the rise in atmospheric CO<SUB>2</SUB> occurred in three sudden steps, each of 10 to 15 parts per million. Every step took place in less than two centuries and was followed by no notable change in atmospheric CO<SUB>2</SUB> for about 1,000 to 1,500 years. Slow, millennial-scale ventilation of Southern Ocean CO<SUB>2</SUB>-rich, deep-ocean water masses is thought to have been fundamental to the rise in atmospheric CO<SUB>2</SUB> associated with the glacial termination, given the strong covariance of CO<SUB>2</SUB> levels and Antarctic temperatures. Our data establish a contribution from an abrupt, centennial-scale mode of CO<SUB>2</SUB> variability that is not directly related to Antarctic temperature. We suggest that processes operating on centennial timescales, probably involving the Atlantic meridional overturning circulation, seem to be influencing global carbon-cycle dynamics and are at present not widely considered in Earth system models.
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