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침자극이 난소를 절제한 흰쥐의 혈청 중 성 hormone 함량에 미치는 영향
김미려,양재하 慶山大學校 基礎科學硏究所 1998 基礎科學 Vol.2 No.1
흰주의 난소를 절제하여 골다공증을 유발한 뒤, 4주 동안 부인과 질환과 근골계질환의 치료에 쓰고 있는 삼음교(SP6)혈과 양릉천(GB34)혈을 침자극하여 혈청 중 성 hormone 함량 변화에 대한 영향을 살펴보았다. 난소절제 후에 혈청 중 estradiol, androstenedione, testosterone 함량이 유의하게 감소하는데, 난소절제 후에 삼음교(SP6)혈과 양릉천(GB34)혈을 침자극하면 혈청 중 androstenedione, testosterone 함량이 난소절제군보다 유의하게 증가되었으며, estradiol의 함량도 증가되었다. 삼음교(SP6)혈과 양릉청(GB34)의 침자극은 난소를 절제한 흰쥐에서 골대사와 관련이 있는 혈중 estrogen 및 전구체인 androstenedione, testosterone 함량을 증가 시킴으로써 난소절제 후, 또는 폐경 후 골다공증의 개선제로 이용될 수 있을 것으로 생각된다. The effect of acupuncture at Sanyinjiao(SP6) and Yanglingquan(GB34) on serum levels of sex hormones was investigated in ovariectomized rats. An elevation of androstenedione, testosterone and estradiol was elecited in ovariectomized rats after 2 and 4 weeks of acupncture treatment, respectively. These results show the possibility that acupncture can play a role of ameliorating osteoporosis by elevating serum levels of sex hormones related with bone metabolism.
구자가 卵巢摘出로 誘發된 흰쥐의 骨多孔症에 미치는 影響 (2)
徐富一,金先熙,卞晟僖,金美麗 대한본초학회 1998 大韓本草學會誌 Vol.13 No.2
This study was performed to investigate the effects of Allii Tuberosi Semen(菲子) on osteoporosis after ovariectomy in rats. Control group received a daily po administration of normal saline for 4 weeks after oophorectomy(OVX). The other experimental group received a daily po administration of water extract of Allii Tuberosi Semen for 4 weeks after oophorectomy(OVX-ATS). Therefore, we measured levels of calcium, phosphorus, ash weights in femur. These results were as follows : 1. In the level of bone phosphorus, the result of OVX was 63.85±1.86㎎/㎗, but the result of OVX-ATS was 68.18±0.85㎎/㎗. But there was no statistical significance. 2. In the level of bone calcium, the result of OVX was 141.66±2.19㎎/㎗, but the result of OVX-ATS group was 164.82±3.74㎎/㎗. And the result of OVX-ATS showed significant increase in comparison with OVX. 3. In the level of bone ash weight, the result of OVX was 0.31±0.005(g), but the result of OVX-ATS was 0.33±0.002(g). And the result of OVX-ATS showed significant increase in comparison with OVX. The observations from these studies and the past studies(=A study on the effects of Allii Tuberosi Semen in ovariectomized osteoporosis of rats) suggest possible protective effect of Alli Tuberosi Semen water extract against bone loss in ovariectomized rats.
증례(證例) : 한방차의 여성 생리통 완화에 대한 임상체험 평가
김미려 ( Mi Ryeo Kim ) 대구한의대학교 제한동의학술원 2012 東西醫學 Vol.37 No.1
Objective: The object of this study was to investigate the efficacy of oriental herb tea in women with dysmenorrhea. Methods: 52 women with dysmenorrhea drank oriental herb tea twice daily for 1 month. The premenstrual symptoms and degree, VAS (Visual Analog Scale) and MVRS (Multidismensional Verbal Rating Scale) of dysmenorrhea was evaluated before and after treatment. And the Affinity of the product was investigated. Results: After treatment, premenstrual mood disorder, degree and duration time of dysmenorrhea and disorder of daily living and sleeping was reduced. And repurchase opinion of the product was 60.4%. Conclusion: These result suggest that drinking oriental herb tea is useful for improvement dysmenorrhea. Also it is needed the various attempts to change formulation, as well as development of herbal tea using medicinal herbs for reducing dysmenorrhea.
이미자 ( Mi-ja Lee ),최문열 ( Moon-yeol Choi ),김유진 ( Yoo Jin Kim ),김미려 ( Mi Ryeo Kim ),유왕근 ( Wang Keun Yoo ) 대구한의대학교 제한동의학술원 2021 東西醫學 Vol.46 No.1
Objective : a-MSH (alpha-melanocyte-stimulating hormone) and IBMX (3-lsobutyl-1-methylxanthine) were known as regulating melanogenesis and differentiation, but they were restricted usage because of stability. So, natural products have developed about regulating melanogenesis and differentiation. Therefore, we investigated about effect of Achyramthis Radix (AR) ethanol extract on gray hair. Methods : a-MSH was used as a positive control. We set up the safe concentration range by MTT assay and conducted melanin contents and tyrosinase activity in mouse melanoma (B16F10) cells. Results : As results, melanin contents were increased in Achyramthis Radix ethanol extract (AR) group contrast to control group. Also, AR group is higher than control group on tyrosinase activity. Conclusion : Our results suggest that AR could be used as a potential material for the treatment of gray hair by increasing the melanogenesis of B16F10 cells.