Interlanguage Features of Chinese EFL Learners in the Communicative Act of Refusal

Meizi Piao 한국응용언어학회 2016 응용 언어학 Vol.32 No.3

The purpose of the present study was to determine how the refusal strategies and linguistic forms used by Chinese EFL learners vary from those of American English speakers. Data was obtained by the elicitation method of open role plays and subsequently, the responses based on the interlocutors’ social status were analyzed. Participants were composed of four groups: 12 native speakers of Chinese (NC), 12 Chinese EFL learners with intermediate proficiency level (CE-I), 12 Chinese EFL learners with higher proficiency level (CE-H), and 12 native speakers of American English (NE). In general, the results indicated that EFL learners differed from native speakers of English in terms of L2 language use. Regarding the content of the semantic formulas, the native Chinese and Chinese EFL learners both chose more specific, family-oriented reasons to mitigate the face-threatening power of refusals, while native English speakers preferred vaguer reasons in the speech act of refusals. Regarding the linguistic forms employed by the participants, native English speakers tended to use hesitators, the modal verb ‘could’, and down toners more frequently than Chinese EFL learners. The Chinese EFL learners, on the other hand, employed the cajoler ‘you know’ and minus committers more frequently than native English speakers.

Rumex hanus by. Extract Protects Against Chronic Alcohol-Induced Liver Injury in Mice

Meizi Piao,Fengwu Wang,Lingyue Shan,Yang Deng,Tiejun Chen 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.7

Alcoholic liver disease (ALD) has become a global health problem. The hepatoprotective effects of bioactive ingredients extracted from Rumex hanus by. on chronic alcoholic liver injury was investigated for the first time. The extract from R. hanus by. (ERHB) was obtained by 70% ethanol extraction, and the endotoxin antagonism rate of ERHB was 88.94 ± 1.24% in vitro. The animal experiments demonstrated that ERHB promoted hepatic function by significantly enhancing the activities of alcohol dehydrogenase and acetaldehyde dehydrogenase, and by reducing the activities of cytochrome P450 proteins, alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase. Furthermore, ERHB improved alcohol-induced dyslipidemia by regulating lipid metabolism. In addition, ERHB ameliorated the alcohol-induced liver injury by inhibiting endotoxin-caused inflammation. Seven compounds with antagonistic activity on endotoxin were identified in ERHB. These results demonstrated that ERHB had protective effects on ALD and if the results can be confirmed in humans, it might be useful as a functional food supplement for ALD treatment.

Preventive Effects of Taemyeongcheong (Korean Traditional Healthy Juice) Extracts on Dextran Sulfate Sodium Induced Colitis in Balb/c Mice

MeiZi Cui,SinJeong Kim,Yong-Kyu Kim,Kun-Young Park 한국식품영양과학회 2013 한국식품영양과학회 학술대회발표집 Vol.2013 No.11

Antiobesity effects of kimchi in diet-induced obese mice

Meizi Cui,김희영,이경희,정지강,황지희,여규영,류병희,최정호,박건영 한국식품연구원 2015 Journal of Ethnic Foods Vol.2 No.3

Background: The present study was investigated to confirm the antiobesity effect of kimchi in high-fat diet-induced obese C57BL/6 mice. Methods: Mice in the high-fat diet (HFD) group, standardized kimchi (S-Kimchi) group, and Korean commercial kimchi (D-Kimchi) group, but not in the normal-diet group, were fed a high-fat diet (HFD) for the first 4 weeks to induce obesity. From the 5th to 8th weeks, the S- and D-Kimchi groups were fed an HFD containing 10% of S-Kimchi or D-Kimchi, respectively. After 8 weeks, mice were sacrificed and obesity-related factors were determined. Results: Body and adipose tissue weights were significantly lower in the kimchi-treated groups than in the HFD group. In particular, in the D-Kimchi group, serum levels of triglyceride, total cholesterol, low-density lipoprotein-cholesterol, insulin, and leptin were significantly lower, and serum levels of high-density lipoprotein-cholesterol and adiponectin were markedly higher than those in the HFD group. Moreover, hepatic mRNA expression of adipogenesis-related genes (CCAAT/enhance-binding protein-α, peroxisome proliferator-activated receptor-γ, sterol regulatory element-binding protein-1c, and fatty acid synthase) in the kimchi-treated groups were lower than those in the HFD group, but fatty acid oxidation-related carnitine palmitoyltransferase-1 expressions were higher. In addition, kimchi decreased the mRNA levels of the inflammation-related monocyte chemotactic protein-1 and interleukin-6 in epididymal fat tissue. Conclusion: Administration of kimchi, especially of D-Kimchi, which contained Leuconostoc mesenteroides DRC 0211 starter and other subingredients, exhibited antiobesity activity by reducing body weight gains and adipose tissue weights; modulating serum lipid profiles and hepatic lipogenesis; regulating serum insulin, leptin, and adiponectin levels; and reducing adipocyte size and inflammatory response in epididymal fat tissues.

Transcriptional repression of vimentin gene expression by pyrroline dithiocarbamate during 12-O-tetradecanoyl-phorbol-13-acetate-dependent differentiation of HL-60 cells

Zheng, Meizi,Son, Mee-Young,Park, Chung,Park, Jong-Il,Jo, Eun-Kyeong,Yoon, Wan-Hee,Park, Seung-Kiel,Hwang, Byung-Doo,Lim, Kyu 충남대학교 암연구소 2006 암연구소 업적집 Vol.5 No.-

Vimentin is a member of the intermediate filament family, and the NF-kB binding site is located in the human vimentin promoter. To gain insight into the role of NF-kB in the regulation of the vimentin gene during 12-O-tetra-decanoylphorbol-13-acetate (TPA)-dependent differentiation of HL-60 cells, the effect of pyrrolidine dithiocarbametc (PDTC) has been investigated using Northern blot hybridization and DNA mobility shift assay. PDTC inhibited macrophage-like morphologic change of HL-60 cells by TPA. TPA-dependent increase of vimentin mRNA level was decreased in a time- and dose-dependent manner by pretreatmcnt with PDTC. One DNA-protcin complex was formed by DNA mobility shift assay when the NF-kB or AP-1 binding sites were incubated with nuclear extract prepared from TPA-treated HI-60 cells, hut no protein bound in control HL-60 cells without TPA. After PDTC pretreatmcnt. NF-kB binding activity vanished but AP-I binding activity was unchanged. Taken together, these results suggest that NF-kB may be an essential transacting factor for transcriptional repression of the vimentin gene by PDTC during TPA-dependent differentiation of HL-60 cells.

Transcriptional repression of vimentin gene expression by pyrroline dithiocarbamate during 12-O-tetradecanoyl-phorbol-13-acetate-dependent differentiation of HL-60 cells

Zheng, Meizi,Son, Mee-Young,Park, Chung,Park, Jong-Il,Jo, Eun-Kyeong,Yoon, Wan-Hee,Park, Seung-Kiel,Hwang, Byung-Doo,Lim, Kyu 충남대학교 암공동연구소 2006 암공동연구소 업적집 Vol.5 No.

Vimentin is a member of the intermediate filament family, and the NF-kB binding site is located in the human vimentin promoter. To gain insight into the role of NF-kB in the regulation of the vimentin gene during 12-O-tetra-decanoylphorbol-13-acetate (TPA)-dependent differentiation of HL-60 cells, the effect of pyrrolidine dithiocarbametc (PDTC) has been investigated using Northern blot hybridization and DNA mobility shift assay. PDTC inhibited macrophage-like morphologic change of HL-60 cells by TPA. TPA-dependent increase of vimentin mRNA level was decreased in a time- and dose-dependent manner by pretreatmcnt with PDTC. One DNA-protcin complex was formed by DNA mobility shift assay when the NF-kB or AP-1 binding sites were incubated with nuclear extract prepared from TPA-treated HI-60 cells, hut no protein bound in control HL-60 cells without TPA. After PDTC pretreatmcnt. NF-kB binding activity vanished but AP-I binding activity was unchanged. Taken together, these results suggest that NF-kB may be an essential transacting factor for transcriptional repression of the vimentin gene by PDTC during TPA-dependent differentiation of HL-60 cells.

對韓漢語介詞敎學的若幹思考

姜美子(Jiang, Meizi) 한국중국어교육학회 2014 중국어교육과연구 Vol.0 No.19

Teaching of form words is the key point of teaching foreigners Chinese grammar and also an important link of grammar teaching in Korean and Chinese Language. In Chinese, there is a lack of morphological changes. Word order and form words are important means for expressing grammar significance. Chinese preposition whose number is about 100 is a kind of form words. They not only take up a high rate of form words but also appear some differences in internal morphology, usage and function between each other. Korean expresses its grammar relation through additional elements (auxiliary word, suffix and so on).The sentence elements of Korean arrange freely in both position and word order. The differences between Chinese and Korean make it hard for Korean Students to use or study preposition, because there is no preposition in their mother tongue. At present, the research on biased errors in Korean students’ learning of Chinese preposition appears increasingly. At the same time people do much further study on the types, reasons and teaching strategies of them. These research which based on interlanguage theory got some rules and countermeasure through error analysis of corpus. Their theoretical basis and research Methods are undoubtedly scientific but has some problems. This paper embarks from the reflection of previous research results and investigate the types and the reasons of Chinese preposition learning for Korean students. It follows the rules of the combination of semantic, syntax and pragmatic. In order to research Korean students’ learning of Chinese preposition, it also uses the method of Chinese internal comparition and comparison analysis of Chinese and Korean languages. In the end, this paper makes a further discussion of Chinese preposition learning for Korean students and tries to help them learn it easier.

Purification and Characterization of a Protease Produced by a Planomicrobium sp. L-2 from Gut of Octopus vulgaris

Qing Liu,Shujing Sun,Meizi Piao,Ji Young Yang 한국식품영양과학회 2013 Preventive Nutrition and Food Science Vol.18 No.4

Protease widely exists in the digestive tract of animals and humans, playing a very important role in protein digestion and absorption. In this study, a high protease-producing strain Planomicrobium sp. L-2 was isolated and identified from the digestive tract of Octopus variabilis. The strain was identified by physiological and biochemical experiments and 16S rDNA sequences analysis. A protease was obtained from the strain Planomicrobium sp. L-2 through ammonium sulfate precipitation, dialysis and enrichment, DEAE-Sephadex A50 anion-exchange chromatography, and Sephadex G-100 gel chromatography. The molecular weight and properties of the protease were characterized, including optimum temperature and pH, thermal stability, protease inhibitions and metal ions. According to our results, the protease from Planomicrobium sp. L-2 strain designated as F1-1 was obtained by three-step separation and purification from crude enzyme. The molecular weight of the protease was 61.4 kDa and its optimum temperature was 40℃. The protease F1-1 showed a broad pH profile for casein hydrolysis between 5.0∼11.0. No residual activity was observed after incubation for 40 min at 60℃ and 60 min at 50℃. F1-1 protease was inhibited by Mn<SUP>2+</SUP>, Hg<SUP>2+</SUP>, Pb<SUP>2+</SUP>, Zn<SUP>2+</SUP>, and Cu2+ ions, as well as PMSF, indicating that the protease F1-1 was a serine protease. Additionally, research basis provided by this study could be considered for industrial application of octopus intestinal proteases.

Antiobesity Effects of Kimchi Inoculated with Leuconostoc mesenteroides on Diet-Induced Obesity in C57BL/6J Mice

Hyun Ah Lee,Cui Meizi,Kyung-Hee Lee,Hee-Young Kim,Ji-Kang Jeong,Ji-Hee Hwang,Kyu-Young Yeo,Byung-Hee Ryu,Jung-Ho Choi,Kun-Young Park 한국식품영양과학회 2014 한국식품영양과학회 학술대회발표집 Vol.2014 No.10

현미 및 율무 함유 생식이 영양불균형이 유도된 흰쥐의 체내 지질농도, 항산화체계 및 면역기능에 미치는 영향

박진영(Jinyoung Park),양미자(Meizi Yang),전혜승(Hye Seung Jun),이진희(Jin-Hee Lee),배희경(Hee-Kyung Bae),박태선(Taesun Park) 한국식품영양과학회 2003 한국식품영양과학회지 Vol.32 No.2

본 연구에서는 sub-optimal 수준의 비타민과 무기질을 섭취하며, 고콜레스테롤 식이에 알코올 섭취를 병행하여 영양 불균형이 유도된 흰쥐를 대상으로 현미와 율무로 구성된 생식 또는 열처리생식을 식이에 첨가하여 5주간 사육시킨 후 체내 지질농도, 항산화체계 및 면역기능에 미치는 영향을 평가하여 다음과 같은 결과를 얻었다. 영양불균형대조군의 식이효율은 일반대조군에 비해 더 낮았고, 현미 및 율무 함유생식 또는 열처리생식을 첨가한 결과 영양불균형대조군에 비해 식이효율이 유의적으로 증가하였다(p<0.05). 혈청 총콜레스테롤 농도는 일반생식군 또는 열처리생식군에서 영양불 균형대조군에 비해 각각 24% 또는 16% 유의적으로 감소하였고(p<0.05) LDL+VLDL-콜레스테롤 농도 역시 일반생식군에서 영양불균형대조군에 비해 26% 유의적으로 감소하였으나(p<0.05), atherogenic index에는 유의적인 차이가 없었다. 일반생식군의 간조직 콜레스테롤 농도는 영양불균형 대조군에 비해 16% 유의적으로 감소하였다(p<0.05). 간조직의 지질과산화물 농도는 일반생식군 또는 열처리생식군에서 영양불균형대조군에 비해 각각 38% 또는 59% 유의적으로 감소하였다(p<0.05). 한편, 영양불균형대조식이에 일반생식 또는 열처리생식을 첨가한 결과 간조직의 항산화효소계 활성에 유의적인 영향을 미치지 못하였다. 장간막임파절의 CD4^+ T-세포 분포 및 CD4^+/CD8^+ 비율은 일반생식군에서 영양불균형대조군에 비해 유의적으로 증가한 반면(p<0.05), 열처리생식군과 영양불균형대조군 간에는 유의적 차이가 없었다. 이상의 결과를 종합해 보면 열처리를 하지 않은 현미 및 율무 함유 생식은 열처리생식에 비해 영양불균형 흰쥐의 체내 콜레스테롤 농도 저하효과 및 장간막임파절의 면역활성도 증가효과가 더 우수한 것으로 나타냈다. Physiological functions of raw grain diet composed of brown rice and Job’s Tear (1 : 1) were evaluated in rats raised with nutritionally unbalanced diet including 1% cholesterol, high proportion of animal lipids (lard: soybean oil = 8 : 2), sub-optimal levels of vitamin and mineral mixture along with 0.5% ethanol in drinking water for 4 weeks. Control rats were fed the AIN-93G diet for 9 weeks, and nutritionally unbalanced rats were divided into 3 groups, and fed one of the following diets with 0.5% ethanol in drinking water for another 5 weeks: unbalanced control diet (UCD), raw grain diet (RGD)(UCD+20% brown rice and Job's Tear mixture, and cooked grain diet (CGD)(autoclaved RGD at 121℃ for 3 hrs). Feeding UCD for 5 weeks significantly lowered the food efficiency ratio (FER) of rats than the value for control animals, and dietary supplementation of brown rice and Job's Tear mixture to UCD significantly restored the FER. Serum total cholesterol concentration was significantly lowered in rats fed RGD (24% decrease) or CGD (16% decrease) compared to the value for rats fed UCD. Feeding RGD for 5 weeks significaly lowered the serum LDL+VLDL-cholesterol concentration (26% decrease), as well as the hepatic cholesterol level (16% decrease) than the values for UCD rats. Animals fed CGD (38% decrease) or RGD (59% decrease) showed significantly lower level of hepatic thiobarbituric acid reactive substances (TBARS) compared to the value for rats fed UCD (p<0.05), although hepatic activities of antioxidative enzymes were not influenced by dietary supplementation. Feeding RGD for 5 weeks significantly increased CD4^+ T-cell population along with CD4^+/CD8^+ ratio of mesenteric lymph nodes compared to those for UCD rats (p<0.05). In conclusion, dietary supplementation of brown rice and Job's Tear mixture as raw grains exhibited superior activity lowering blood and hepatic levels of cholesterol, and improving mesenteric lymph nodes immune function of rats to the cooked grain mixture of identical ingredients.