Comparison of Arbekacin and Vancomycin in Treatment of Chronic Suppurative Otitis Media by Methicillin Resistant Staphylococcus aureus

황지희,이주형,황정환,정경민,이은정,윤용주,문미경,김주신,원경숙,이창섭 대한의학회 2015 Journal of Korean medical science Vol.30 No.6

Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of ear infections. We attempted to evaluate the clinical usefulness of arbekacin in treating chronic suppurative otitis media (CSOM) by comparing its clinical efficacy and toxicity with those of vancomycin. Efficacy was classified according to bacterial elimination or bacteriologic failure and improved or failed clinical efficacy response. Ninety-five subjects were diagnosed with CSOM caused by MRSA. Twenty of these subjects were treated with arbekacin, and 36 with vancomycin. The bacteriological efficacy (bacterial elimination, arbekacin vs. vancomycin: 85.0% vs. 97.2%) and improved clinical efficacy (arbekacin vs. vancomycin; 90.0% vs. 97.2%) were not different between the two groups. However, the rate of complications was higher in the vancomycin group (33.3%) than in the arbekacin group (5.0%) (P = 0.020). In addition, a total of 12 adverse reactions were observed in the vancomycin group; two for hepatotoxicity, one for nephrotoxicity, eight for leukopenia, two for skin rash, and one for drug fever. It is suggested that arbekacin be a good alternative drug to vancomycin in treatment of CSOM caused by MRSA.

일 지역사회의 자살기도자와 자살사망자에 대한임상적 특성 비교

황지희,기선완,이기환,김지웅,이태용 대한우울조울병학회 2010 우울조울병 Vol.8 No.2

Objectives:Suicide is an important public health problem and one of the leading causes of death worldwide. The purpose of this study was to examine the differences in clinical and sociodemographic characteristics between suicide attempters and completers in Chungcheongnam-Do Community. Methods:This study was a part of the Mental Health Survey of Chungcheongnam-Do. 73 subjects (33 attempters, 40 completers) were investigated with a questionnaire about suicide related factors. Basic sociodemographic and clinical datas were compared between suicide attempters and suicide completers. Results:The suicide completers were characterized by male preponderance,lower rates of previous suicide attempt and psychiatric treatment. In both groups, depression were strongly related to suicide. The most common method of suicide in both groups wasagricultural chemicalsoverdose. In addition, the suicide completers used the lethal methods such as Hanging, drowning, neck fastened and jumping compare to attempters. Howeverthe suicide attempters used the non-severe methods such as psychotropics overdose and cutting. Economic problems were a leading cause of suicide in both groups. Also, impulsivity and despair were most common psychological state at the time of suicide. Conclusion:There were significant differences between suicide attempters and completers in gender, distressful disease, method of suicides, previous suicide attempts. This result emphasis the need for further investigation on high risk group for suicide.

The possible grammaticalization of Spanish discourse marker o sea

황지희 서울대학교 라틴아메리카연구소 2022 이베로아메리카硏究 Vol.33 No.2

The present study is based on the hypothesis that one of the most frequently used discourse markers in contemporary Spanish, o sea, exhibits the possible process of grammaticalization. Grammaticalization can be defined as a linguistic phenomenon in which a lexical item becomes a grammatical one, or an already grammatical item becomes an even more grammatical one along the process of language change. Through both diachronic and synchronic analyses of frequency of uses, it was shown that there had been a dramatic increase in the frequency of o sea specifically in oral contexts, which serves as a trigger for the beginning of grammaticalization. Based on this finding, a quantitative corpus analysis of various uses of o sea in authentic oral speeches was conducted. The results confirmed that the discourse marker in question revealed most of the characteristics of grammaticalization: ‘desemantization’ or ‘semantic bleaching’ shown by the change from a conjunction word to a discourse marker with its semantic meaning equivalent to es decir and a saber, and to an unmarked filler word with no semantic meaning; ‘extension’ demonstrated by the fact that o sea has gained various pragmatic functions over time; ‘decategorization’ reflected in some of the innovative ways of writing; and some subtle but noticeable ‘phonemic reduction’.

실내 아이스링크의 극초미세입자의 농도분석

황지희,임완령,이기영 대한보건협회 2011 대한보건협회 보건종합학술대회 Vol.2011 No.-

[연구배경] 실내 아이스링크장은 제한된 실내 공간으로 계절에 상관없이 스케이트를 즐길 수 있는 장소이다. 최상의 빙질을 유지하기 위해 실내 아이스링크장에서 반드시 필요한 작업인 정빙은 가솔린이나 프로판과 같은 화석연료로 작동되는 정빙기계로 이루어지는데, 기계 가동 시 연료의 내부 연소로 인하여 인체에 부정적인 영향을 미치는 여러 가지 오염물질들이 배출된다. [연구목적] 본 연구에서는 국내의 실내 아이스링크장을 대상으로 극초미세입자(UFPs, Ultra Fine Particles)의 수 농도를 측정하여 정빙기계 가동에 따른 농도변화를 파악하고자 한다. [연구방법] 국내에 존재하는 실내 아이스링크장 40곳 중 12곳의 실내 아이스링크장에서 측정되었으며, 본 연구는 2009년 3~5월에 수행되었고, 극초미세입자의 측정은 광산란법을 이용한 TSI사의 Model 8525 P-Trak ultrafine particle counter로 측정하였다. 대상 시설의 정빙기계는 프로판을 연료로 하였으며, 정빙으로 인한 극초미세입자 농도의 영향을 보기 위해 적어도 한번 이상의 정빙 시간을 포함하여 각 장소마다 약 4시간 정도 이용객석과 인접한 곳에서 측정하였다. 또한 아이스링크장의 외부에 중요한 발생원이 없음을 확인하기 위해 20분 이상 실외의 극초미세입자 농도를 측정하였다. [연구결과] 측정된 실내 아이스링크장 12곳의 극초미세입자의 평균 수 농도는 30,987 ±16,483 particles/cm3였고, 아이스링크장 외부의 극초미세입자의 평균 수 농도는 16,979 ±5,390 particles/cm3였다. 정빙 횟수가 한번 일 때와 두 번 일 때의 극초미세입자의 평균 수농도는 각각 16,376 와 33,909 particles/cm3로 정빙 횟수에 따라 농도는 유의한 차이를 보였다 (p<0.05). 실내 아이스링크장 12곳의 정빙 시작 시간을 기준으로 농도변화를 분석하여 보면 모두 정빙 시작을 기점으로 농도가 급격하게 증가하였고 시간이 지남에 따라 점점 감소하는 추세를 보였다. 극초미세입자의 12곳 최고 농도 수의 평균은 75,972 particles/cm3로 실내아이스 링크장의 평균 수 농도와 비교하였을 때 약 2.5배 높았다. 프로판가스를 연료로 사용하는 정빙기계 가동에 따른 농도변화를 통해 실내 아이스링크장에서 극초미세입자에 의한 배출오염으로 인한 노출이 큰 것을 알 수 있었다.

선천성 결장 폐쇄증의 경험

황지희,김대연,김성철,김인구,Hwang, Jihee,Kim, Dae-Yeon,Kim, Seong-Chul,Kim, In-Koo 대한소아외과학회 2012 소아외과 Vol.18 No.2

Colonic atresia (CA) is the rare cause of intestinal obstruction, and diagnosis of CA is difficult. But only few research has been performed, so little information has been available. The purposes of this study was to analyze the clinical findings of CA so that help physicians make decision properly. Children with CA who were treated at the division of pediatric surgery at Asan Medical Center in the period from January 1989 to December 2011 were evaluated retrospectively. A total of 6 children were treated with CA. These accounted for 2.7% of all gastrointestinal atresias managed in Asan Medical Center. Only one child was premature and low birth weight, the others were fullterm neonates and showed normal birth weight. Vomiting and abdominal distension were common symptoms and simple X-ray and barium study were used for diagnose of CA. But only 66.7% of the babies were diagnosed as CA pre-operatively. And 2 children out of 6 underwent re-operation due to missed CA at the time of the first operation. In aspect of types of atresia, the type IIIa were two, type IV were two, type I was one case, and one child showed rectal stenosis due to rectal web. Various operations were done according to individual findings and associated diseases. The 50% (n=3) of children underwent the primary anastomosis and the others (n=3) underwent colostomy first and staged operation later for missed CA or associated disease. All of them were recovered any significant complications. Therefore, the prognosis of CA is satisfactory if diagnosis and surgical management could be made properly. But because of the low incidence of CA, delay of diagnosis and treatment may occur. To prevent delay of diagnosis, we suggest prompt evaluation of doubtful infant and careful inspection of distal patency of bowel including whole colon and rectum when operating patients with intestinal atresia at any level.

Polyphenism by the level of predation risk in larval salamander, Hynobius leechii

황지희,김은지,김호진,정훈 한국습지학회 2013 한국습지학회지 Vol.15 No.4

This study examined the cannibalistic polyphenism of larval salamander Hynobius leechii by the level of predation risk. Salamander eggs were collected from three regions (Mountain Inwang, Mountain Surak and Gwangju). Eggs were treated by three different risk conditions: (1) high risk, predation risk three times a day; (2) medium risk, predation risk once a day;and (3) low risk, no predation risk. Predation risk was conducted using a chemical cue from Chinese minnows. The chemical cue treatment started from the day of collection and ended one week after hatching. Post-treatment measurements were head width at the level of the eyes (HWE), largest head width (LHW), and Snout-vent length of the each larva. To compare the morphological change according to the predation risk, we modified the two head size, HWE and LHW, to HWE/LHW. A significant difference in HWE/LHW and snout-vent length was evident according to the level of predation risk. And larval mortality was increase by the predation risk. The results indicate that predation risk can cause cannibalistic polyphenism of larval salamander and this morphological change could influence larval mortality.

모멘텀 슬래밍을 고려한 선체 운동 및 파랑하중 해석

황지희,박인규,구원철 대한조선학회 2011 대한조선학회 학술대회자료집 Vol.2011 No.6

Reactive Power Control Method for Grid-Tie Inverters Using Current Measurement of DG Output

황지희,임성일,최면송,김명수 대한전기학회 2019 Journal of Electrical Engineering & Technology Vol.14 No.2

The penetration ratio of distributed generation (DG) has increased due to the depletion of fossil fuels and the impacts of global warming. Thus, overvoltage at the point of common coupling may occur since reverse current fl ows with the installment of DG. To solve this problem, this paper presents a reactive power control method based on the measured current at the point of common coupling of DG. The purpose of this paper is not to provide methods to improve the voltage profi les of distribution lines through the reactive power control, but to maintain the voltage after the DG connection as before the connection. By applying the proposed method in this paper, it is possible to signifi cantly improve the penetration ratio of DG by restricting the voltage rise. Case studies, using MATLAB simulation, are performed to verify the feasibility of the new reactive power control method.

집단미술활동이 초등학교 아동의 창의성과 학습흥미에 미치는 효과

황지희,공마리아 한국아동심리재활학회 2003 놀이치료연구 Vol.7 No.2

The purpose of this study is to clarify the effect that group art therapy affects creativity and study interest for children in Elementary School. The subjects were selected as 129 children in 3 classrooms (S Elementary School, the 4th grade) in C city, then first with the test about creativity and study interest the treatment group was randomly divided into 2 groups such as experiment group (4 children) and control group (4 children), and homogeneity was verified. The group art therapy program made by this researcher was performed through 20 times of experiments for 10 weeks (2 days a week) in the proprietary art school run by the researcher, and the program was processed through prior test, experiment treatment, posterior test. The treatment methods of the materials used in this study were such as the following. First, posterior test about creativity and study interest between groups for those mean and standard deviation was assessed by t-test. Second, qualitative analysis which analyzes the activity of group art therapy and describes the changes was performed in each experiment. This study suggests the following conclusion. First, group art therapy appeared to improve creativity for children. Second, group art therapy appeared to improve study interest for children. Third, group art therapy appeared to positively affect the changes of creativity and study interest in the activity process of each experiment. Therefore, group art therapy shows the effect on improving creativity and study interest for children. 본 연구는 C시에 소재하고 있는 S초등학교 4학년에 재학중인 3학급(129명)의 아동들에게 창의성, 학습흥미 검사를 실시하여, 동질성을 띤 아동 8명을 대상으로 하였다. 실험집단에게 연구자가 구성한 집단미술활동 프로그램을 주 2회씩 10주, 총 20회기를 120분씩 실시하였다. 본 연구에서 사용한 자료처리 방법은 실험집단과 통제집단 간의 창의성, 학습흥미 사후 검사의 평균 및 표준편차를 산출하고 t-test를 실시하였으며, 또한 회기별 집단미술활동을 분석하고 변화를 관찰하여 기술하는 질적 분석을 하였다. 본 연구에 따르면 집단미술활동이 아동의 창의성을 향상시키는 것으로 나타났으며, 집단미술활동 실시 이후에 창의성이 전체적으로 향상되었고, 네 가지 하위영역 중 융통성과 독창성에서 향상을 보였다. 또한, 집단미술활동이 아동의 학습흥미를 향상시키는 것으로 나타났으며, 집단미술활동 실시 후에 학습흥미가 전체적으로 향상되었고, 학습흥미의 다섯 가지 하위척도 중 사고형 흥미, 탐구형 흥미, 사회형 흥미, 창의형 흥미의 향상이 나타났다. 마지막으로, 회기별 활동과정에서 창의성과 학습흥미의 변화에 긍정적인 영향을 미치는 것으로 나타났다. 집단미술활동과정에서 창의적인 특성과 학습흥미의 특성에 있어 긍정적인 행동변화를 보였다. 따라서 본 연구는 집단미술활동이 아동의 창의성과 학습흥미를 향상시키는 효과가 있음을 시사해 준다.

장애학생의 선발과 배치

황지희 국립특수교육원 2001 현장특수교육 Vol.8 No.3