http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Meera Penumetcha (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Modulation of Leptin Levels by Oxidized Linoleic Acid: A Connection to Atherosclerosis?
Meera Penumetcha,Nadya Merchant,Sampath Parthasarathy 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.4
The objective of the study was to determine the effects of oxidized linoleic acid (Ox-LA) on plasma leptin and to determine the relationship between plasma leptin levels and atherosclerosis in animals treated with Ox-LA. Low-density lipoprotein (LDL) receptor knockout (LDL r^(−/−)) mice were fed a high fat diet with or without Ox-LA for 11 weeks. Plasma leptin levels in the high fat group consuming Ox-LA were significantly higher (14,052 ± 601 pg/mL vs. 10,950 ± 541 pg/mL; P < .01) compared to the group receiving the high fat diet alone. There was a highly significant correlation between the plasma leptin levels and aortic atherosclerotic lesions. From this we conclude that chronic exposure to dietary Ox-LA increases the plasma levels of leptin in LDL r^(−/−) mice on a high fat diet. Considering our previous finding that dietary Ox-LA increased atherosclerosis, the current findings emphasize the need to reduce dietary intake of oxidized fat.
-
Inhibition of Atherosclerosis in Low-Density Lipoprotein Receptor-Negative Mice by Sesame Oil
Sampath Parthasarathy,Shylesh Bhaskaran,Nalini Santanam,Meera Penumetcha 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.4
Diet has profound effects on the development of atherosclerosis. Fatty acid composition, antioxidants, andother components such as lignans have major effects on the atherosclerotic process. Sesame oil has both mono- and polyun-saturated fatty acid constituents in equal proportions. In addition, it also has high levels of numerous antioxidants and induc-ers of peroxisome proliferator-activated receptor. The objective of this study was to determine the anti-atherosclerotic effectsof sesame oil. In this study, male low-density lipoprotein (LDL) receptor (LDLR) . /. mice were fed atherogenic diet oratherogenic diet reformulated with the same level of sesame oil (sesame oil diet). Plasma lipids and atherosclerotic lesionswere quantified after 3 months of feeding. Sesame oil-containing diet significantly reduced the atherosclerotic lesion forma-tion and plasma cholesterol, triglyceride, and LDL cholesterol levels in LDLR . /. mice. These findings suggest that sesameoil could inhibit atherosclerosis lesion formation effectively, perhaps because of the synergistic actions of fatty acid and non-saponifiable components.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
