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Cytotoxicity and antinociceptive activity of Jasminum sambac leaves
Md Rahatul Islam,Razina Rouf,Juwel Barua,Shaikh Jamal Uddin,Mahiuddin Alamgir 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.2
The ethanolic extract of Jasminum sambac leaves were tested for its cytotoxicity and possible antinociceptive activity in experimental animals. The extract showed potent cytotoxic activity in brine shrimp lethality assay and the LC50 was found only 25 mg/ml. The extract significantly and dose dependently inhibited the acetic acid induced writhing in mice (56.83%, P < 0.001 and 43.17%, P < 0.001 for 500 and 250 mg/kg body weight, respectively). The results supported its traditional uses. The ethanolic extract of Jasminum sambac leaves were tested for its cytotoxicity and possible antinociceptive activity in experimental animals. The extract showed potent cytotoxic activity in brine shrimp lethality assay and the LC50 was found only 25 mg/ml. The extract significantly and dose dependently inhibited the acetic acid induced writhing in mice (56.83%, P < 0.001 and 43.17%, P < 0.001 for 500 and 250 mg/kg body weight, respectively). The results supported its traditional uses.
Cytotoxicity and antinociceptive activity of Jasminum sambac leaves
Islam, Md Rahatul,Rouf, Razina,Barua, Juwel,Uddin, Shaikh Jamal,Alamgir, Mahiuddin Kyung Hee Oriental Medicine Research Center 2008 Oriental pharmacy and experimental medicine Vol.8 No.2
The ethanolic extract of Jasminum sambac leaves were tested for its cytotoxicity and possible antinociceptive activity in experimental animals. The extract showed potent cytotoxic activity in brine shrimp lethality assay and the LC50 was found only 25 mg/ml. The extract significantly and dose dependently inhibited the acetic acid induced writhing in mice (56.83%, P < 0.001 and 43.17%, P < 0.001 for 500 and 250 mg/kg body weight, respectively). The results supported its traditional uses.