http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Matthew Bruce (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
Limitations and artifacts in shear-wave elastography of the liver
Matthew Bruce,Orpheus Kolokythas,Giovanna Ferraioli,Carlo Filice,Matthew O’Donnell 대한의용생체공학회 2017 Biomedical Engineering Letters (BMEL) Vol.7 No.2
Recent studies have shown that real-time, twodimensionalshear-wave elastography (2D-SWE) canmonitor liver fibrosis by measuring tissue elasticity (i.e.,elastic modulus). Two clinical studies of 2D-SWE in theliver have shown that there are several practical issues thatcan compromise quantitation of liver tissue elasticity. Bothgeneral ultrasound (US) limitations and limitations in the2D-SWE method itself resulted in significant variability inestimated liver elasticity. The most common US limitationswere: poor acoustic window, limited penetration, and rib/lung shadows. The most common 2D-SWE limitationswere: reverberations under the liver capsule, respiratory/cardiac motion, and vessel pulsation/loss of SWEsignal. Based on these studies, scan protocols have beenoptimized to minimize the influence of these limitations onliver elasticity quantification. These refined protocolsshould move non-invasive SWE closer to becoming thepreferred tool to diagnose and manage many chronic diseasesof the liver.
-
Review : What is the proper work-up of the patient with clinical early stage uterine adenocarcinoma
( Bruce Patsner ),( Matthew L Anderson ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.7
Objective: To discuss the proper preoperative workup of patients with uterine adenocarcinoma who present with disease clinically confined to the uterine corpus. Methods: Review of recommendations suggested in major textbooks in gynecologic oncology over the past thirty five years as well as select recent publications in the gynecologic oncology literature in Asia as well as the United States and Europe. Results: The suggested preoperative testing for the patient population under consideration has evolved over the years depending on whether the patient is at low risk or high risk for occult metastatic disease, Conclusion: Standard preoperative testing is always indicated but preoperative CA-125 and advanced radiological imaging are never routinely indicated for "low risk" patients. Either test may be indicated in select high-risk patients in the setting of clinical investigation though it is unclear which test, if either, provides enough meaningful clinical information which will either alter surgical management or which may be justified in light of the predicted high percentage of patients who will have normal preoperative test results.
-
Kiyota, Naomi,Robinson, Bruce,Shah, Manisha,Hoff, Ana O.,Taylor, Matthew H.,Li, Di,Dutcus, Corina E.,Lee, Eun Kyung,Kim, Sung-Bae,Tahara, Makoto Mary Ann Liebert, Inc. 2017 Thyroid Vol.27 No.9
<P><B><I>Background:</I></B> While there is a clear consensus for defining radioiodine-refractory differentiated thyroid cancer (RR-DTC), it is unknown whether these criteria are equally valid for determining when radioiodine (RAI) therapy is no longer beneficial and systemic treatment should be considered. Lenvatinib, a multikinase inhibitor, significantly prolonged progression-free survival (PFS) compared to placebo in a Phase 3 trial in RR-DTC (SELECT; hazard ratio [HR]: 0.21 [99% confidence interval (CI) 0.14–0.31]; <I>p</I> < 0.001). This sub-analysis compared clinical outcomes of lenvatinib-treated patients in SELECT stratified by RR-DTC inclusion criteria.</P><P><B><I>Methods:</I></B> In SELECT, patients with measurable RR-DTC and radiologic evidence of disease progression ≤13 months prior to study entry were randomized 2:1 to lenvatinib (24 mg/day; 28-day cycle) or placebo. In this analysis, patients were stratified based on the following RR-DTC inclusion criteria: no RAI uptake, disease progression within 12 months of RAI therapy despite RAI avidity at the time of treatment, and extensive (>600 mCi) cumulative RAI exposure. All had disease progression as an inclusion criterion for SELECT.</P><P><B><I>Results:</I></B> Of 392 patients (261 lenvatinib; 131 placebo) enrolled, 275, 235, and 73 patients met the inclusion criteria for no RAI uptake, disease progression despite RAI avidity, and extensive RAI exposure, respectively. There was significant overlap between the patient groups, with 167 (42.6%) patients meeting more than one inclusion criterion. Lenvatinib improved median PFS compared to placebo in all groups (“no RAI uptake”: lenvatinib not quantifiable [NQ; CI 14.8–NQ] vs. placebo, 3.7 months [CI 2.5–5.3]; “disease progression despite RAI avidity”: lenvatinib 16.5 months [CI 12.8–NQ] vs. placebo, 3.7 months [CI 1.9–5.4]; “extensive RAI exposure”: lenvatinib 18.7 months [CI 10.7–NQ] vs. placebo, 3.6 months [CI 1.9–5.5]). Objective response rates were 71.8%, 60.0%, and 56.0% for patients with no RAI uptake, disease progression despite RAI avidity, and extensive RAI exposure, respectively. Lenvatinib-related adverse events were similar across groups.</P><P><B><I>Conclusions:</I></B> Comparable efficacy and safety profiles were observed in lenvatinib-treated patients regardless of RR-DTC criteria, possibly because of a large overlap among patients fulfilling each criterion. However, differing definitions for RR-DTC may be equally valid because both lenvatinib and placebo arms exhibited similar PFS outcomes across groups.</P>
-
( Ryan Bylsma ),( Mustafa Baldawi ),( Bruce Toporoff ),( Matthew Shin ),( Meghan Cochran-yu ),( Davinder Ramsingh ),( Purvi Parwani ),( David G. Rabkin ) 대한외상학회 2021 大韓外傷學會誌 Vol.34 No.2
We present a case of delayed diagnosis of traumatic tricuspid valve rupture in a patient who was emergently brought to the operating room for repair of lacerations to the heart and liver without intraoperative transesophageal echocardiography (TEE). Initial post-operative transthoracic echocardiography (TTE) did not show structural pathology. One week later, TTE with better image quality showed severe tricuspid regurgitation. Subsequently, TEE clearly demonstrated rupture of the anterior papillary muscle and flail anterior tricuspid leaflet. The case description is followed by a brief discussion of the utility of TEE in the setting of blunt thoracic trauma.
KCI
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
