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Contrast-Associated Acute Kidney Injury (CA-AKI) in Children: Special Considerations
Martin Windpessl,Andreas Kronbichler 대한소아신장학회 2019 Childhood kidney diseases Vol.23 No.2
Contrast-associated acute kidney injury (CA-AKI) is a major concern when iodinated contrast material is administered, especially in patients at risk. Efforts have been undertaken to understand the detrimental effects of contrast media (CM). With the use of low-osmolar or iso-osmolar CM the incidence of CA-AKI has steadily decreased within the past decade; however, especially in the pediatric population information is scarce. Incidence rates have been reported to range between 0% to 18.75%, particularly depending on indication, selection of population (i.e. preexisting co-morbidities), and definition of AKI. Different biomarkers have been proposed, but confirmatory studies are either lacking or have contributed to their lack of diagnostic power. Proteomic approaches have been employed and may pave the way to such discovery. Prevention strategies have been tested and proposed, but the recently published AMACING and PRESERVE trials have shown that commonly used strategies (such as systematic hydration or administration of N-acetylcysteine) have no role in the prevention of CA-AKI. We propose that thoughtful assessment of one’s fluid state is the most appropriate approach and depending on the hydration status diuretics or fluid administration should be provided to achieve an euvolemic state ahead of contrast exposure.
Automatic Management of Large Images Databases
Martin Klinkigt,Heiko Maus,Koichi Kise,Andreas Dengel 한국멀티미디어학회 2009 한국멀티미디어학회 국제학술대회 Vol.2009 No.-
With an increasing amount of images a user would like to keep and share the desire for an adequate management for these images raises. The normal folder structure which is available on nowadays computers can fulfill this task only non satisfying. Often an image contains more individual information than can be expressed by a hierarchical tree. We introduce annotation techniques to support the user in this organization. Furthermore, we analyze how a computer system could do this organization automatically to keep the amount of work for the user as low as possible.
Martin Frendø,Andreas Frithioff,Steven Arild Wuyts Andersen 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.4
Performing the first peer review of a plastic surgical research article can be an overwhelming task. However, it is an essential scholarly skill and peer review is used in a multitude of settings: evaluation of journal articles, conference abstracts, and research proposals. Furthermore, peer reviewing provides more than just the opportunity to read and help improve other’s work: peer reviewing can improve your own scientific writing. A structured approach is possible and recommended. In these ten tips, we provide guidance on how to successfully conduct the first peer reviews. The ten tips on peer reviewing concern: 1) Appropriateness: are you qualified and prepared to perform the peer review? 2) Familiarization with the journal and its reviewing guidelines; 3) Gathering first impressions of the paper followed by specific tips for reviewing; 4) the abstract and introduction; 5) Materials, methods, and results (including statistical considerations); and 6) discussion, conclusion, and references. Tip 7 concerns writing and structuring the review; Tips 7 and 8 describe how to provide constructive criticism and understanding the limits of your expertise. Finally, Tip 10 details why—and how—you become a peer reviewer. Peer review can be done by any plastic surgeon, not just those interested in an academic career. These ten tips provide useful insights for both the aspiring and the experienced peer reviewer. In conclusion, a systematic approach to peer reviewing is possible and recommended, and can help you getting started to provide quality peer reviews that contribute to moving the field of plastic surgery forward.
Gray State Dynamics in the Blinking of Single Type I Colloidal Quantum Dots
Martin Belitsch,Christian Gruber,Harald Ditlbacher,Andreas Hohenau,Joachim R. Krenn 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.4
We analyze the photoluminescence intermittency (blinking) of single colloidal CdSe/ZnS quantum dots (QDs). Two distinct emission levels, a bright on-state and a low-intensity gray state, correspond to monoexponential decay times of 58 ns and 4 ns, respectively. The ratio gray/on states increases upon increasing excitation intensity. Conversely, the gray/on level intensity ratio increases upon coupling to a plasmonic nanostructure, while the states maintain their monoexponential character. Corroborated by data from a CdSeTe/ZnS QD, our results demonstrate that type I QDs can indeed show a gray (rather than completely dark) emission level with a distinct monoexponential decay, a point that is discussed controversially in the literature.
Andreas Argubi-Wollesen,Bettina Wollesen,Martin Leitner,Klaus Mattes 한국산업안전보건공단 산업안전보건연구원 2017 Safety and health at work Vol.8 No.1
The purpose of this review is to name and describe the important factors of musculoskeletal strain originating from pushing and pulling tasks such as cart handling that are commonly found in industrial contexts. A literature database search was performed using the research platform Web of Science. For a study to be included in this review differences in measured or calculated strain had to be investigated with regard to: (1) cart weight/ load; (2) handle position and design; (3) exerted forces; (4) handling task (push and pull); or (5) task experience. Thirteen studies met the inclusion criteria and proved to be of adequate methodological quality by the standards of the Alberta Heritage Foundation for Medical Research. External load or cart weight proved to be the most influential factor of strain. The ideal handle positions ranged from hip to shoulder height and were dependent on the strain factor that was focused on as well as the handling task. Furthermore, task experience and subsequently handling technique were also key to reducing strain. Workplace settings that regularly involve pushing and pulling should be checked for potential improvements with regards to lower weight of the loaded handling device, handle design, and good practice guidelines to further reduce musculoskeletal disease prevalence.
Size-selected gold clusters on porous titania as the most “gold-efficient” heterogeneous catalysts
Dollinger, Andreas,Stolch, Lukas,Luo, Yuan,Beck, Martin,Strobel, Christoph H.,Hagner, Matthias,Dilger, Stefan,Bein, Malin,Polarz, Sebastian,Gantefoer, Gerd F.,Kim, Young-Dok,Proch, Sebastian The Royal Society of Chemistry 2014 Physical chemistry chemical physics Vol.16 No.22
<P>Research on homogeneous and heterogeneous catalysis is indeed convergent and finds subnanometric particles to be at the heart of catalytically active species. Here, monodisperse gold clusters are deposited from the gas phase onto porous titania generating well-defined model systems and the resulting composite materials exhibit a sharp size-dependency on the number of gold atoms per cluster and exceptionally high-turnovers toward the bromination of 1,4-dimethoxybenzene are observed. This indicates that the deliberate generation of active centres is of utmost importance for the creation of the most “gold-efficient” catalysts.</P> <P>Graphic Abstract</P><P>Size-selected gold clusters on titania present highly efficient solution phase catalysts for bromination with NBS reaching TONs of enzymes. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cp00597j'> </P>
Andrew Martin Lunn,Ann Urmston,Steven Seymour,Andrea Manfrin 한국보건의료인국가시험원 2020 보건의료교육평가 Vol.17 No.-
Purpose: This study aimed to evaluate the impact of Patient as teacher (PAT) sessions on the knowledge, communication skills, andparticipation of pharmacy students in the United Kingdom. Methods: During the academic year 2019–2020, year 1 and 2 pharmacy students at the University of Central Lancashire were invitedto complete a questionnaire following PAT sessions. Data were analyzed by means of descriptive statistics, including mean and standarddeviation for: continuous variables and reliability analysis. Pearson’s chi-square or Fisher exact test, odds ratio, and phi were used for analyzing dichotomous variables. Thematic analysis was used for free text comments. Results: Sixty eight of 228 students participated (response rate of 29.8%). No statistical difference was found between gender(P=0.090); a statistically significant difference was found between year (P=0.008). Cronbach’s α (0.809) confirmed a good internalconsistency. Ninety-seven percent of the students learned a lot, and 85.3% appreciated and valued the PAT sessions; 89.7% wantedmore sessions. Ninety-two point seven percent perceived the sessions to contextualize their learning. Five questions were dichotomizedby grouping the responses into negative and positive; 90.3% of responses were positive and did not show statistically significant differences in gender and year of study. Overall students’ free text comments were positive, but active listening and consultation appeared inthe positive and negative domains, highlighting the need for more student engagement. Conclusion: PAT sessions had a positive impact on students’ knowledge, communication skills and participation, and contextualizedlearning. They provide a valuable contribution to the pharmacy students’ experience in the United Kingdom.
Contrast-Associated Acute Kidney Injury (CA-AKI) in Children: Special Considerations
Windpessl, Martin,Kronbichler, Andreas Korean Society of Pediatric Nephrology 2019 Childhood kidney diseases Vol.23 No.2
Contrast-associated acute kidney injury (CA-AKI) is a major concern when iodinated contrast material is administered, especially in patients at risk. Efforts have been undertaken to understand the detrimental effects of contrast media (CM). With the use of low-osmolar or iso-osmolar CM the incidence of CA-AKI has steadily decreased within the past decade; however, especially in the pediatric population information is scarce. Incidence rates have been reported to range between 0% to 18.75%, particularly depending on indication, selection of population (i.e. preexisting co-morbidities), and definition of AKI. Different biomarkers have been proposed, but confirmatory studies are either lacking or have contributed to their lack of diagnostic power. Proteomic approaches have been employed and may pave the way to such discovery. Prevention strategies have been tested and proposed, but the recently published AMACING and PRESERVE trials have shown that commonly used strategies (such as systematic hydration or administration of N-acetylcysteine) have no role in the prevention of CA-AKI. We propose that thoughtful assessment of one's fluid state is the most appropriate approach and depending on the hydration status diuretics or fluid administration should be provided to achieve an euvolemic state ahead of contrast exposure.