A Tuber Lectin from Arisaema jacquemontii Blume with Anti-insect and Anti-proliferative Properties

( Manpreet Kaur ),( Kuljinder Singh ),( Pushpinder Jai Rup ),( Sukhdev Singh Kamboj ),( Ajit Kumar Saxena ),( Madhunika Sharma ),( Madhulika Bhagat ),( Sarvesh Kumar Sood ),( Jatinder Singh ) 생화학분자생물학회 2006 BMB Reports Vol.39 No.4

3D printed stretching-dominated micro-trusses

Kaur, Manpreet,Yun, Tae Gwang,Han, Seung Min,Thomas, Edwin L.,Kim, Woo Soo Elsevier 2017 Materials & Design Vol.134 No.-

<P><B>Abstract</B></P> <P>Micro-architectures, such as cellular truss structures, enhance the mechanical properties of structural materials while ensuring that they are lightweight in nature. Among others, stretching-dominated truss structures are known for their high modulus and yield strength, which makes them the best choice for lightweight structural applications. Finite element analysis of octahedral vs. octet structures is used to compare the differences in stress distribution in the stretching-dominated deformation of such trusses. Both octahedral and octet stretching-dominated structures were fabricated by fused deposition modeling (FDM)-based three-dimensional (3D) printing. These micro-architectures are printed with different polymeric materials, such as polylactic acid or polylactide (PLA), nylon 618, and a carbon fiber reinforced composite of PLA (CFRPLA). In addition, the CFRPLA filament with randomly suspended carbon fibers in PLA undergoes shear-induced alignment along the strut direction of the 3D printed micro-trusses, which leads to an improved Young's modulus as compared to the other materials. The properties of the 3D printed stretching-dominated micro-trusses are evaluated by compression testing, finite element analysis (FEA), and thermal analysis. The 3D printed octet structure of CFRPLA with fiber alignment exhibits the highest modulus and yield strength of 0.6GPa and 17MPa, respectively.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Stretch-dominated and bending-dominated micro-trusses are fabricated by FDM-based 3D printing with 100 micrometers in strut diameter. </LI> <LI> Stretch-dominated octet micro-truss is mechanically programed by 3D printing with rigid and soft materials </LI> <LI> 3D printed CFRP truss shows strengthened mechanical properties resulted from shear-induced alignment of fibers along the 3D printing direction. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

A Review of Cloud Computing Security Issues

Manpreet Kaur,Hardeep Singh 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.5

Cloud Computing is an emerging paradigm which has become today’s hottest research area due to its ability to reduce the costs associated with computing. In today’s era, it is most interesting and enticing technology which is offering the services to its users on demand over the internet. Since Cloud computing stores the data and its disseminated resources in the environment, security has become the main obstacle which is hampering the deployment of cloud environments. There are number of users used cloud to store their personal data, so that data storage security is required on the storage media. The major concern of cloud environment is security during upload the data on cloud server. Data storage at cloud server attracted incredible amount of consideration or spotlight from different communities. For outsourcing the data there is a need of third party. The importance of third party is to prevent and control unauthorized access to data store to the cloud. This research paper discusses the security issues of cloud storage.

A Tuber Lectin from Arisaema jacquemontii Blume with Anti-insect and Anti-proliferative Properties

Kaur, Manpreet,Singh, Kuljinder,Rup, Pushpinder Jai,Kamboj, Sukhdev Singh,Saxena, Ajit Kumar,Sharma, Madhunika,Bhagat, Madhulika,Sood, Sarvesh Kumar,Singh, Jatinder Korean Society for Biochemistry and Molecular Biol 2006 Journal of biochemistry and molecular biology Vol.39 No.4

A tuber lectin from Arisaema jacquemontii Blume belonging to family Araceae was purified by employing a single step affinity chromatography using column of asialofetuin-linked amino activated silica beads and the bound lectin was eluted with 100 mM glycine-HCl buffer pH 2.5. The purified A. jacquemontii lectin (AJL) showed a single protein band with an apparent molecular mass of 13.4 kDa when submitted to SDS-polyacrylamide gel electrophoresis under reducing as well as non-reducing conditions. The native molecular mass of AJL determined by gel filtration on a Biogel P-200 column was 52 kDa and its carbohydrate content was estimated to be 3.40%. Thus AJL is a tetrameric glycoprotein. The purified lectin agglutinated erythrocytes from rabbit but not from human. Its activity was not inhibited by any of the mono- and disaccharides tested except N-acetyl-D-lactosamine having minimal inhibitory sugar concentration (MIC) 25 mM. Among the glycoproteins tested only asialofetuin was found to be inhibitory (MIC $125\;{\mu}g/mL$). A single band was obtained in native PAGE at pH 4.5 while PAGE at pH 8.3 showed two bands. Isoelectric focusing of AJL gave multiple bands in the pI range of 4.6-5.5. When incorporated in artificial diet AJL significantly affected the development of Bactrocera cucurbitae (Coquillett) larvae indicating the possibility of using this lectin in a biotechnological strategy for insect management of cucurbits. Larvae fed on artificial diet containing sub-lethal dose of AJL showed a significant decrease in acid phosphatase and alkaline phosphatase activity while esterase activity markedly increased as compared to larvae fed on diet without lectin. Out of various human cancer cell lines employed in sulphorhodamine B (SRB) assay, this lectin was found to have appreciable inhibitory effect on the in vitro proliferation of HCT-15, HOP-62, SW-620, HT-29, IMR-32, SKOV-3, Colo-205, PC-3, HEP-2 and A-549 cancer cell lines by 82, 77, 73, 70, 41, 41, 37, 29, 21 and 21% respectively.

Simulative Investigation of 32x10, 32x20 and 32x40 Gb/s DWDM Systems with Dispersion Compensating Fibers

Manpreet Kaur,Himali Sarangal 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.8

Dense wavelength division multiplexing (DWDM) is a WDM technology with reduced channel spacing. This technology is really scalable in terms of handling additional wavelengths/users. But the dispersion compensation is a key issue in DWDM at bit rate ≥ 10 Gb/s. Dispersion can be fully compensated by using Dispersion compensating fiber as a compensator. In this paper, the performance of 32 channel DWDM system with post-dispersion compensation using DCF at different bit rates (10, 20 and 40 Gbps) is investigated. The simulation is done in Optisystem simulator. The performance of the simulated system has been investigated in terms of quality (Q) factor and bit error rate (BER).

Roles of Galectin-7 in Cancer

Kaur, Manpreet,Kaur, Tarnjeet,Kamboj, Sukhdev Singh,Singh, Jatinder Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.2

Galectins are ${\beta}$-galactoside binding lectins that contain one or more carbohydrate recognition domains. As a consequence of sugar-binding properties, galectins exhibit a variety of interactions with glycoproteins, thus playing important roles in various pathological processes. A number of studies have shown roles of galectins in cancer. Galectin-7 is a prototype member of the galectin family implicated in epithelial stratification and cell migration. It can act as a potent dual regulator in different types of cancer. Galectin-7 may contribute either to neoplastic transformation and tumour progression through regulation of cell growth, cell cycle, angiogenesis, apoptosis and cell migration or may have a protective effect in cancer depending on the tissue type. A perusal of the literature indicates particular roles of galectin-7 in carcinomas and melanomas, while contributions await greater exploration in other types of cancers including sarcomas and leukemia. This review collectively summarizes available literature on expression and roles of galectin-7 in different cancers.

Three-dimensionally printed cellular architecture materials: perspectives on fabrication, material advances, and applications

Kaur, Manpreet,Han, Seung Min,Kim, Woo Soo Cambridge University Press (Materials Research Soc 2017 MRS Communications Vol.7 No.1

<▼1><B>Abstract</B><P/></▼1><▼2><P>Three-dimensional (3D) printing generates cellular architected metamaterials with complex geometries by introducing controlled porosity. Their ordered architecture, imitative from the hierarchical high-strength structure in nature, defines the mechanical properties that can be coupled with other properties such as the acoustic, thermal, or biologic response. Recent progress in the field of 3D architecture materials have advanced that enables for design of lightweight materials with high strength and stiffness at low densities. Applications of these materials have been identified in the fields of ultra-lightweight structures, thermal management, electrochemical devices, and high absorption capacity.</P></▼2>

Tuning the band energetics of size dependent titania nanostructures for improved photo-reductive efficiency of aromatic aldehydes

Manpreet Kaur Aulakh,Bonamali Pal 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.80 No.-

Mono-dispersed and smaller sized TiO2 nanospheres (~8 nm and ~20 nm) exhibited superior photo-reductive efficiency for few aromatic aldehydes under UV light. It has been found that pnitrobenzaldehydeand benzaldehyde are efficiently reduced to p-aminobenzyl alcohol (80% and 61%)and benzyl alcohol (59% and 38%) by 8 nm and 20 nm particles respectively, relative to negligiblereduction by TiO2 (P25) under same experimental conditions. However, the successful photo-reductionof p-nitrotoluene (97%) was observed with P25 whose reduction potential ( 0.5 eV) lies below theconduction band (CB,0.85 eV vs NHE) of the catalyst. Thesefindings can be explained on the basis ofunsuitable and mismatched CB of P25 with respect to the lowest unoccupied molecular orbital ofCHOgroup to access its photo-activity. However, this hydrogenation occurred by synthesized smaller sizedTiO2 particles (~8 nm and~20 nm) due to their favorable band gap (3.85 eV and 3.62 eV) and conductionband edge ( 0.61 eV and0.50 eV). Moreover, the other physio-chemical characteristics of 8 nm and20 nm sized particles such as surface area (323 m2 g 1 and 297 m2 g 1), higher charge carrier relaxationtime (61 ms and 40 ms) are also co-related for ease of photo-activity relative to TiO2 (P25).

Sequential microbial-photocatalytic degradation of imidacloprid

Teena Sharma,Manpreet Kaur,Amit Sobti,Anita Rajor,Amrit Pal Toor 대한환경공학회 2020 Environmental Engineering Research Vol.25 No.4

In the present study, the application of sequential biological and photocatalytic process was evaluated as a feasible process for the degradation of imidacloprid (IMI) in soil. Photocatalysis was carried out as a post and pre-treatment to the biological process as Microbial Photocatalytic (MP) and Photocatalytic Microbial (PM), respectively, to enhance the degradation and mineralization of IMI in soil. By both the processes, there was an enhancement in the percentage degradation of IMI i.e 86.2% for PM and 94.6% for MP process. The obtained results indicate that MP process is apparently more efficient in degradation of IMI which was observed with 15 days of biological treatment followed by 18 h of photocatalytic degradation (15 d + 18 h). The present work also reveals that though the difference in terms of the degradation of IMI after 5 d + 18 h, 10 d + 18 h & 15 d+ 18 h of MP process is not drastic, yet significant variation has been observed in terms of mineralization that truly signifies the removal of IMI from the soil. The LC analysis has shown that the intermediates formed during MP process are more and smaller in comparison to PM process, which further provides evidence that MP process is better than PM process for effective degradation of IMI in soil.

Hierarchically Designed Electron Paths in 3D Printed Energy Storage Devices

Park, Seong Hyeon,Kaur, Manpreet,Yun, Dongwon,Kim, Woo Soo American Chemical Society 2018 Langmuir Vol.34 No.37

<P>Three-dimensional (3D) microsupercapacitors (MSC) have been spotlighted, because they overcome limited areal capacitance of two-dimensional planar MSCs. Specially, 3D printing technology offers numerous advantages to generate 3D electrodes for MSCs, which includes time-saving, cost-effective manufacturing, and realization of tailorable complex electrode designs. In this paper, we report novel hierarchical 3D designs of conductive 3D electrodes for MSC by digital light processing (DLP)-based 3D printing. Photocurable composite resin with silver nanowires was optimized for DLP printing for the hierarchical design of high aspect ratio in 3D electrodes. The hierarchical 3D electrodes showed unique patterns on the structure corresponding to stacking of layers in the direction of 3D printing. The fabricated 3D MSCs demonstrated low electrical resistance to be used as feasible MSC electrodes. Energy storage from silver redox reactions was demonstrated in hierarchical 3D electrodes designed with mechanically durable 3D octet trusses.</P> [FIG OMISSION]</BR>