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      • KCI등재후보

        Evaluation of Banana Hypersensitivity Among a Group of Atopic Egyptian Children: Relation to Parental/Self Reports

        Zeinab A. El-Sayed,Dalia H El-Ghoneimy,Dina El-Shennawy,Manar W. Nasser 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.3

        Purpose: To evaluate the frequency of banana sensitization and allergy among a group of atopic Egyptian children in relation to parental/self reports. Methods: This is a case-control study included 2 groups of allergic children with and without history of banana allergy, each included 40patients. They were subjected to skin prick test (SPT) using commercial banana allergen extract and prick-prick test (PPT) using raw banana, in additionto measuring the serum banana-specific IgE. Oral banana challenge was performed in suspected cases. Results: Banana allergy was diagnosedin 3 (7.5%) patients based on positive history of allergy on exposure to banana, positive SPT/PPT and elevated banana-specific IgE. The 3 patientshad bronchial asthma with exacerbation upon banana exposure. The PPT results conform with those of SPT both in diagnosis of banana allergy andin the skin reactivity to banana. Serum banana-specific IgE was detectable in the whole studied sample with higher serum level among those withouthistory of banana allergy (P=0.005). Oral banana challenge was negative for 20 patients with history of banana allergy and positive serum banana-specific IgE but negative SPT and PPT. Conclusions: Self/parental reports of banana allergy is high while the actual banana allergy is uncommon. The PPT seems as reliable as SPT in diagnosis of banana allergy unlike specific IgE which reflects sensitization rather than allergy. Oralfood challenge remains the most helpful tool for diagnosis of food allergy in suspected cases.

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