Impulse Controllability and Impulse Elimination in Rectangular Descriptor Systems

Vikas Kumar Mishra,Nutan Kumar Tomar,Mahendra Kumar Gupta 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10

In this paper, a decomposition of system matrices of linear time invariant rectangular descriptor systems is proposed. Using the decomposition, a technique is developed to check the impulse controllability for rectangular descriptor systems. Necessary and sufficient conditions are stated and proved to design a proportional plus derivative feedback such that the closed loop system is free of impulse. Examples are given to illustrate the presented theory.

Reference range of random urinary calcium creatinine ratio in North Indian children and adolescents

Raman Kumar Marwaha,Mahendra Kumar Garg,Navin Dang,Ambrish Mithal,Aditi Chadha,Nandita Gupta,Manchanda Raj Kumar 대한소아내분비학회 2019 Annals of Pediatirc Endocrinology & Metabolism Vol.24 No.1

Purpose: Urinary calcium creatinine ratio (UCaCrR) is a reliable indicator for monitoring hypercalciuria following vitamin D supplementation. However, the reference range varies from region to region. Previous studies did not take vitamin D and parathyroid hormone status into account while evaluating UCaCrR. Hence, we undertook this study to establish the 95th percentile of UCaCrR as an indicator of hypercalciuria in North Indian children and adolescents. Methods: Four hundred seventy-three participants (boys 62.2%, girls 37.8%) with adequate dietary calcium intake, normal serum levels of 25-hydroxy-vitamin D (>20 ng/mL), and without secondary hyperparathyroidism following supplementation were selected for evaluation of UCaCrR. Results: The mean age and body mass index of subjects were 11.2±2.6 years and 18.0±3.6 kg/m 2 , respectively. The 95th percentile of UCaCrR in the study population was 0.126. The mean, median, and 95th percentile of UCaCrR was significantly higher in prepubertal children (age ≤10 years) (0.0586±0.0374, median=0.0548, 95th percentile=0.136) compared to those >10 years old (0.0503±0.0363, median=0.0407, 95th percentile=0.123, P=0.02). No significant difference in UCaCrR was observed between genders and different weight categories. Conclusion: UCaCrR of 0.13 defines the cutoff value for hypercalciuria in North Indian children and adolescents with adequate dietary intake of calcium and sufficient serum vitamin D levels.

Effect of Neem (Azadirachta indica) oil on the progressive growth of a spontaneous T cell lymphoma

Mallick, Sanjaya Kumar,Gupta, Vivekanand,Singh, Mahendra Pal,Vishvakarma, Naveen Kumar,Singh, Nisha,Singh, Sukh Mahendra Kyung Hee Oriental Medicine Research Center 2008 Oriental pharmacy and experimental medicine Vol.7 No.5

The present study was undertaken to investigate the effect of in vivo administration of neem oil intra-peritoneally (i.p.) to mice bearing a progressively growing transplantable T cell lymphoma of spontaneous origin, designated as Daltons lymphoma (DL), on the tumor growth. Mice were administered various doses of neem oil mixed in groundnut oil, which was used as a diluting vehicle or for administration to control DL-bearing mice. Administration of neem oil resulted in an acceleration of tumor growth along with a reduction in the survival time of the tumor-bearing host. Neem oil administered DL-bearing mice showed an augmented apoptosis in splenocytes, bone marrow cells and thymocytes along with an inhibition in the anti-tumor functions of tumor-associated macrophages. Thus this study gives an altogether a novel information that neem oil instead of the popular belief of being anti-tumor and immunoaugmentary may in some tumor-bearing conditions, behave in an opposite way leading to an accelarated tumor progression along with a collapse of the host's anti-tumor machinery. These observations will thus have long lasting clinical significance, suggesting caution in use of neem oil for treatment of cancer.

Impact of scaling and root planing on C-reactive protein levels in gingival crevicular fluid and serum in chronic periodontitis patients with or without diabetes mellitus

Mahendra Mohan,Rajesh Jhingran,Vivek Kumar Bains,Vivek Gupta,Rohit Madan,Iram Rizvi,Kanchan Mani 대한치주과학회 2014 Journal of Periodontal & Implant Science Vol.44 No.4

Purpose: The present study was conducted to evaluate the impact of scaling and root planing (SRP) on the C-reactive protein (CRP) levels of gingival crevicular fluid (GCF) and serum in chronic periodontitis patients with type 2 diabetes mellitus (T2DM-CP) or without type 2 diabetes mellitus (NDM-CP). Methods: Forty-eight human participants were divided into two groups: an experimental (T2DM-CP) group (group I, n=24) comprising chronic periodontitis patients with random blood sugar ≥200 mg/dL and type 2 diabetes mellitus, and control (NDM-CP) group (group II, n=24) of those with chronic periodontitis and random blood sugar <200 without T2DM for the study. All subjects underwent nonsurgical periodontal therapy (NSPT) including complete SRP and subgingival debridement. Periodontal health parameters, plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), GCF volume (GCF vol), GCF-CRP, random blood glucose (RBS), glycated hemoglobin, and systemic inflammatory markers, serum CRP, total leukocyte count (TLC), neutrophil count (Neutr) and lymphocyte count (Lymph), were evaluated at baseline, 1 month, and 3 months after SRP. Results: NSPT resulted in statistically significant improvement in periodontal health parameters (PI, GI, PPD, CAL, GCF vol), CRP levels in serum as well as GCF of both groups I and II. The mean improvement in periodontal health parameters (PI, GI, PPD, CAL, GCF vol), CRP levels in serum and GCF was greater in group I than group II after NSPT. There was nonsignificant increase in GCF-CRP, TLC, Lymph, and RBS, and a significant increase in Neutr and Serum CRP in group II at 1 month. The Serum CRP level of 20 out of 24 group II patients had also increased at 1 month. Conclusions: The CRP levels in both GCF and serum were higher in T2DM-CP patients than in NDM-CP patients. Although there was a significant improvement in both the groups, greater improvement was observed in both GCF and serum samples of T2DM-CP patients.

Impact of scaling and root planing on C-reactive protein levels in gingival crevicular fluid and serum in chronic periodontitis patients with or without diabetes mellitus

Mohan, Mahendra,Jhingran, Rajesh,Bains, Vivek Kumar,Gupta, Vivek,Madan, Rohit,Rizvi, Iram,Mani, Kanchan Korean Academy of Periodontology 2014 Journal of Periodontal & Implant Science Vol.44 No.4

Purpose: The present study was conducted to evaluate the impact of scaling and root planing (SRP) on the C-reactive protein (CRP) levels of gingival crevicular fluid (GCF) and serum in chronic periodontitis patients with type 2 diabetes mellitus (T2DM-CP) or without type 2 diabetes mellitus (NDM-CP). Methods: Forty-eight human participants were divided into two groups: an experimental (T2DM-CP) group (group I, n=24) comprising chronic periodontitis patients with random blood sugar ${\geq}200mg/dL$ and type 2 diabetes mellitus, and control (NDM-CP) group (group II, n=24) of those with chronic periodontitis and random blood sugar <200 without T2DM for the study. All subjects underwent nonsurgical periodontal therapy (NSPT) including complete SRP and subgingival debridement. Periodontal health parameters, plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), GCF volume (GCF vol), GCF-CRP, random blood glucose (RBS), glycated hemoglobin, and systemic inflammatory markers, serum CRP, total leukocyte count (TLC), neutrophil count (Neutr) and lymphocyte count (Lymph), were evaluated at baseline, 1 month, and 3 months after SRP. Results: NSPT resulted in statistically significant improvement in periodontal health parameters (PI, GI, PPD, CAL, GCF vol), CRP levels in serum as well as GCF of both groups I and II. The mean improvement in periodontal health parameters (PI, GI, PPD, CAL, GCF vol), CRP levels in serum and GCF was greater in group I than group II after NSPT. There was nonsignificant increase in GCF-CRP, TLC, Lymph, and RBS, and a significant increase in Neutr and Serum CRP in group II at 1 month. The Serum CRP level of 20 out of 24 group II patients had also increased at 1 month. Conclusions: The CRP levels in both GCF and serum were higher in T2DM-CP patients than in NDM-CP patients. Although there was a significant improvement in both the groups, greater improvement was observed in both GCF and serum samples of T2DM-CP patients.

Evaluation of Somaclonal Variation for Genetic Improvement of Patchouli (Pogostemon patchouli), an Exclusively Vegetatively Propagated Aromatic Plant

Nagawara Seshagirirao Ravindra,Srinivas Iyer Ramesh,Mahesh Kumar Gupta,Tripta Jhang,Ashutosh Kumar Shukla,Mahendra Pandurang Darokar,Raghavendra Narayanrao Kulkarni 한국작물학회 2012 Journal of crop science and biotechnology Vol.15 No.1

Patchouli (Pogostemon patchouli) is an important, exclusively vegetatively propagated aromatic plant, whose essential oil is wide-ly used in perfumery and cosmetic products. Forty SC 1 generation (first generation following in vitro phase) somaclones selected ran-domly from about 400 somaclones developed from the variety Johore, were multiplied through stem cuttings and evaluated in SC 2and SC 3 generations to study the extent of somaclonal variation generated for plant height, herb yield, essential oil content, essential oil yield, and seven constituents of the essential oil. Significant or highly significant somaclonal variation was observed for plant height, herb yield, essential oil content, essential oil yield, and contents of patchouli alcohol, α-guaiene, α,δ-patchoulene, and α-bul-nesene in the essential oil. The number of somaclones significantly superior to the parental variety for plant height, herb yield, essen-tial oil content, and patchouli alcohol content in the essential oil ranged from 8 - 16 and the maximum superiority over the parental variety for these traits ranged from 21 - 79%. Broad-sense heritability estimates of plant height, herb yield, and essential oil content were 0.60 - 0.70 while those of essential oil yield and patchouli alcohol content were 0.44 and 0.47, respectively. Heritability esti-mates of other studied essential oil constituents were generally low (0.12 - 0.38). A high positive correlation was observed between essential oil yield and herb yield suggesting that selection for herb yield would be effective in improving essential oil yield. Patchouli alcohol content in the essential oil was negatively correlated with all the studied traits. Somaclonal variation, heritabilities of traits,and inter-trait correlations are reported for the first time in patchouli.

Evaluation of Somaclonal Variation for Genetic Improvement of Patchouli ($Pogostemon$ $patchouli$), an Exclusively Vegetatively Propagated Aromatic Plant

Ravindra, Nagawara Seshagirirao,Ramesh, Srinivas Iyer,Gupta, Mahesh Kumar,Jhang, Tripta,Shukla, Ashutosh Kumar,Darokar, Mahendra Pandurang,Kulkarni, Raghavendra Narayanrao 한국작물학회 2012 Journal of crop science and biotechnology Vol.15 No.1

Patchouli ($Pogostemon$ $patchouli$) is an important, exclusively vegetatively propagated aromatic plant, whose essential oil is widely used in perfumery and cosmetic products. Forty $SC_1$ generation (first generation following $in$ $vitro$ phase) somaclones selected randomly from about 400 somaclones developed from the variety Johore, were multiplied through stem cuttings and evaluated in $SC_2$ and $SC_3$ generations to study the extent of somaclonal variation generated for plant height, herb yield, essential oil content, essential oil yield, and seven constituents of the essential oil. Significant or highly significant somaclonal variation was observed for plant height, herb yield, essential oil content, essential oil yield, and contents of patchouli alcohol, ${\alpha}$-guaiene, ${\alpha}$,${\delta}$-patchoulene, and ${\alpha}$-bulnesene in the essential oil. The number of somaclones significantly superior to the parental variety for plant height, herb yield, essential oil content, and patchouli alcohol content in the essential oil ranged from 8 - 16 and the maximum superiority over the parental variety for these traits ranged from 21 - 79%. Broad-sense heritability estimates of plant height, herb yield, and essential oil content were 0.60 - 0.70 while those of essential oil yield and patchouli alcohol content were 0.44 and 0.47, respectively. Heritability estimates of other studied essential oil constituents were generally low (0.12 - 0.38). A high positive correlation was observed between essential oil yield and herb yield suggesting that selection for herb yield would be effective in improving essential oil yield. Patchouli alcohol content in the essential oil was negatively correlated with all the studied traits. Somaclonal variation, heritabilities of traits, and inter-trait correlations are reported for the first time in patchouli.

High Frequency Plantlet Regeneration from Nodal Segment Culture of Female Momordica dioica (Roxb.)

Mahipal S. Shekhawat,Narpat S. Shekhawat,Harish,Kheta Ram,Mahendra Phulwaria,Amit Kumar Gupta 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.2

An in vitro propagation method for female plants of Momordica dioica (Roxb.) has been established. The nodal segments were harvested and the cut ends of the explants were sealed with wax and then surface sterilized and cultured. Bud breaking occurred on Murashige and Skoog's (MS) agar-gelled medium + 2.0 mg L^(-1) 6-Benzylaminopurine (BAP) + 0.1 mg L^(-1) Indole-3 acetic acid (IAA). The cultures were amplified by passages on MS medium supplemented with 1.0 mg L^(-1) BAP + 0.1 mg L^(-1) IAA. Further, shoot amplification (29.2 shoots per vessel) was achieved by subculturing of in vitro regenerated shoot clump on MS medium + 0.5 mg L^(-1) BAP + 0.1 mg L^(-1) IAA. The micropropagated shoots were subsequently transferred for root formation on half-strength MS medium + 2.0mg L^(-1) Indole-3 butyric acid (IBA) with 89% success rate. The in vitro-regenerated shoots were also rooted ex vitro with 34% success. These plantlets were hardened in the greenhouse and transferred to the field. The established protocol is suitable for true to type cloning of mature female plant of M. dioica.

High Frequency Plantlet Regeneration from Nodal Segment Culture of Female Momordica dioica (Roxb.)

Shekhawat, Mahipal S.,Shekhawat, Narpat S.,Harish, Harish,Ram, Kheta,Phulwaria, Mahendra,Gupta, Amit Kumar 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.2

An in vitro propagation method for female plants of Momordica dioica (Roxb.) has been established. The nodal segments were harvested and the cut ends of the explants were sealed with wax and then surface sterilized and cultured. Bud breaking occurred on Murashige and Skoog's (MS) agar-gelled medium + 2.0 mg $L^{-1}$ 6-Benzylaminopurine (BAP) + 0.1 mg $L^{-1}$ Indole-3 acetic acid (IAA). The cultures were amplified by passages on MS medium supplemented with 1.0 mg $L^{-1}$ BAP + 0.1 mg $L^{-1}$ IAA. Further, shoot amplification (29.2 shoots per vessel) was achieved by subculturing of in vitro regenerated shoot clump on MS medium + 0.5 mg $L^{-1}$ BAP + 0.1 mg $L^{-1}$ IAA. The micropropagated shoots were subsequently transferred for root formation on half-strength MS medium + 2.0 mg $L^{-1}$ Indole-3 butyric acid (IBA) with 89% success rate. The in vitro-regenerated shoots were also rooted ex vitro with 34% success. These plantlets were hardened in the greenhouse and transferred to the field. The established protocol is suitable for true to type cloning of mature female plant of M. dioica.