RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • Computational Methods for Patient-Specific Perfusion Simulations of Coronary Arteries

        Hyun Jin Kim(김현진),L. Papamanolis,C. Jaquet,M. Sinclair,M. Schaap,I. Danad,P. van Diemen,P. Knaapen,L. Najman,H. Talbot,C. A. Taylor,I. E. Vignon-Clementel 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.4

        Patient-specific computational simulations of blood flow are utilized to diagnose and predict treatment outcomes of coronary artery disease. The computational simulations, however, are limited when estimating perfusion in the myocardium as multiscale vessels from arteries to capillaries need to be developed. We propose a multiscale patient-specific computational model framework to simulate blood flow from large coronary arteries to myocardial tissues. Patient vasculatures were segmented from coronary computed tomography angiography data and then extended from the image-based model down to the arteriole level using a space-filling synthetic forest of arterial trees. Blood flow is modelled by coupling a 1-D model of the coronary arteries to a single-compartment Darcy myocardium model. Simulated results for 5 patients with non-obstructive coronary artery disease are compared to [<sup>15</sup>O]H<sub>2</sub>O PET exam data for both resting and hyperemic conditions. Results on a patient with a severe disease demonstrate coronary artery disease can predict myocardial regions with perfusion deficit. This multiscale computational model of simulating blood flow from the epicardial coronary arteries to the left ventricle myocardium will be further validated and applied to human data.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼