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M. Salman Siddiqui,Adil Rasheed,Trond Kvamsdal 한국풍공학회 2019 Wind and Structures, An International Journal (WAS Vol.29 No.6
Aerodynamic characteristic of a small scale wind turbine under the influence of an incoming uniform wind field is studied using k-ω Shear Stress Transport turbulence model. Firstly, the lift and drag characteristics of the blade section consisting of S826 airfoil is studied using 2D simulations at a Reynolds number of 1×105. After that, the full turbine including the rotational effects of the blade is simulated using Multiple Reference Frames (MRF) and Sliding Mesh Interface (SMI) numerical techniques. The differences between the two techniques are quantified. It is then followed by a detailed comparison of the turbine's power/thrust output and the associated wake development at three tip speeds ratios (λ = 3, 6, 10). The phenomenon of blockage effect and spatial features of the flow are explained and linked to the turbines power output. Validation of wake profiles patterns at multiple locations downstream is also performed at each λ. The present work aims to evaluate the potential of the numerical methods in reproducing wind tunnel experimental results such that the method can be applied to full-scale turbines operating under realistic conditions in which observation data is scarce or lacking.
In Vitro Cholinomimetic Effect of Loranthus Ferrugineus in Isolated Guinea Pig Ileum
Omar Ziad Ameer,Ibrahim M. Salman,Mohammad Jamshed Ahmad Siddiqui,Mun Fei Yam,Raghava Naidu Sriramaneni,Amirin Sadikun,Zhari Ismail,Amin Malik Shah,Mohd. Zaini Asmawi 사단법인약침학회 2009 Journal of Acupuncture & Meridian Studies Vol.2 No.4
This study aimed to elucidate the mechanism(s) of the spasmogenic action of Loranthus ferrugineus in isolated guinea pig ileum. Thus the contractile responses of guinea pig ileum to graded additions of either L. ferrugineus methanol extract or its n-butanol fraction were tested in the presence and absence of various pharmacological interventions. The data showed that L. ferrugineus methanol extract and the n-butanol fraction produced a concentration-dependent spasmogenic effect in isolated guinea pig ileum segments. These effects were significantly inhibited in the presence of 1 μM atropine. In contrast, the response to the lowest concentrations of L. ferrugineus methanol extract (0.25, 0.5 and 1 mg/mL) and n-butanol fraction of L. ferrugineus (0.125, 0.25 and 0.5 mg/mL) were considerably enhanced in the presence of 0.05 μM neostigmine. Neither L. ferrugineus methanol extract nor n-butanol fraction contractile responses were affected upon the incubation of the ileal segments with 100 μM hexamethonium. The results of this study show that the spasmogenic effect of L. ferrugineus is possibly mediated through a direct action on intestinal muscarinic receptors. It is suggested that the bioactive constituents of L. ferrugineus serve as a substrate for acetylcholinesterase. This study aimed to elucidate the mechanism(s) of the spasmogenic action of Loranthus ferrugineus in isolated guinea pig ileum. Thus the contractile responses of guinea pig ileum to graded additions of either L. ferrugineus methanol extract or its n-butanol fraction were tested in the presence and absence of various pharmacological interventions. The data showed that L. ferrugineus methanol extract and the n-butanol fraction produced a concentration-dependent spasmogenic effect in isolated guinea pig ileum segments. These effects were significantly inhibited in the presence of 1 μM atropine. In contrast, the response to the lowest concentrations of L. ferrugineus methanol extract (0.25, 0.5 and 1 mg/mL) and n-butanol fraction of L. ferrugineus (0.125, 0.25 and 0.5 mg/mL) were considerably enhanced in the presence of 0.05 μM neostigmine. Neither L. ferrugineus methanol extract nor n-butanol fraction contractile responses were affected upon the incubation of the ileal segments with 100 μM hexamethonium. The results of this study show that the spasmogenic effect of L. ferrugineus is possibly mediated through a direct action on intestinal muscarinic receptors. It is suggested that the bioactive constituents of L. ferrugineus serve as a substrate for acetylcholinesterase.