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        An Optimization Algorithm for Solving High-Dimensional Complex Functions Based on a Multipopulation Cooperative Bare-Bones Particle Swarm

        Liu Cong,Liu Yunqing,Wu Tong,Yan Fei,Zhang Qiong 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.4

        The particle swarm optimization (PSO) algorithm can easily become trapped in a local optimum when the objective function to be optimized is high-dimensional and complex. A multipopulation, cooperative, bare-bones particle swarm optimization (MCBBPSO) algorithm is proposed to solve this problem. In MCBBPSO, three types of parallel cooperative learning populations are used to optimize the objective function. By adding disturbance factors and adopting an elite reverse learning strategy, the optimization ability of the algorithm is increased. Through the “mirror wall” method, the cross-boundary particles are processed to reduce the loss of particle resources. Experiments using the CEC2013 standard test functions demonstrate the convergence accuracy and speed of the algorithm on high-dimensional and complex objective functions. Finally, MCBBPSO is applied to perform parameter optimization in support vector regression (SVR), and short-term wind speeds are then predicted using the optimized SVR approach to reduce resource consumption in a power grid.

      • KCI등재

        The precipitation of three Ca-P phase whiskers from an acid solution through hydrolysis of urea

        Yunqing Kang,Yunshan Liu,Zhongbing Huang,Yadong Yao,Xiaoming Liao,Li Liao,Guangfu Yin 한양대학교 세라믹연구소 2008 Journal of Ceramic Processing Research Vol.9 No.2

        Hydroxyapatite (HA), beta-tricalcium phosphate (β-TCP) and dicalcium phosphate (DCP) whiskers with high aspect ratio and good crystallinity were successfully prepared by hydrolysis of urea in acid solutions at 90oC for 96 h. The precipitated whiskers were characterized by XRD, SEM and TEM. The lengths and aspect ratios of whiskers could be controlled by the precipitation agent, urea, with a proper incubation time. Results revealed good morphology and crystallinity of the precipitated whiskers without any impurities. TEM indicated single crystal diffraction patterns of HA and β-TCP were clearly identified. The high aspect ratio of whiskers could be potentially used as the scaffold in tissue engineering or filler in composite biomaterials to enhance mechanical properties. Hydroxyapatite (HA), beta-tricalcium phosphate (β-TCP) and dicalcium phosphate (DCP) whiskers with high aspect ratio and good crystallinity were successfully prepared by hydrolysis of urea in acid solutions at 90oC for 96 h. The precipitated whiskers were characterized by XRD, SEM and TEM. The lengths and aspect ratios of whiskers could be controlled by the precipitation agent, urea, with a proper incubation time. Results revealed good morphology and crystallinity of the precipitated whiskers without any impurities. TEM indicated single crystal diffraction patterns of HA and β-TCP were clearly identified. The high aspect ratio of whiskers could be potentially used as the scaffold in tissue engineering or filler in composite biomaterials to enhance mechanical properties.

      • Gold nanorods functionalized by a glutathione response near-infrared fluorescent probe as a promising nanoplatform for fluorescence imaging guided precision therapy

        Huang, Yan,Liu, Qingluan,Wang, Yunqing,He, Na,Zhao, Rongfang,Choo, Jaebum,Chen, Lingxin The Royal Society of Chemistry 2019 Nanoscale Vol.11 No.25

        <P>Theranostics nanoplatforms offer opportunities for imaging-guided precision therapy and hold great potential for clinical applications. In most reported works, the imaging unit has a lack of site selectivity, and is always kept in the “on” modality regardless of whether it is in normal tissues or tumor sites, increasing the risk of unsafe treatment. Herein, we designed a near-infrared (NIR) fluorescence-guided theranostics nanoplatform by integrating the functions of tumor-response and photodynamic therapy (PDT)/photothermal therapy (PTT). A novel NIR fluorescent dye, CyPT, with excellent optical and PDT/PTT properties, was synthesized and linked onto the gold nanorods (AuNRs) to form CyPT-AuNRs nanohybrids<I>via</I>a sulfur-sulfur bond that can be broken by glutathione (GSH) with high selectivity and sensitivity. In normal cells where the concentration of GSH is low, the fluorescence of CyPT is quenched by the AuNRs. By contrast, the high level of GSH in tumor cells leads to the breaking of the sulfur-sulfur bond, resulting in the release of CyPT and the accomplishment of a “off-on” fluorescence response. Followed by precise NIR tumor-imaging diagnosis, the PDT and PTT treatment which rely on the released CyPT and AuNRs, respectively, can be effectively performed. The CyPT-AuNRs nanoplatform has been successfully applied to the treatment of tumor xenograft models and no distinct damage has been observed in the nearby normal tissues. This versatile nanoplatform has potential for use in targeted tumor imaging and precision therapy.</P>

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        Supercritical CO2 extraction and response surface optimization of ginkgolic acids from ginkgo biloba exopleura

        Lufei Tian,Minghao Zhou,Xiaomei Pan,Guomin Xiao,Yunqing Liu 한국화학공학회 2015 Korean Journal of Chemical Engineering Vol.32 No.8

        Supercritical (Sc)-CO2 extraction was adopted to extract ginkgolic (G.) acids from ginkgo biloba exopleura. Response surface optimization was employed to maximize extraction recovery of G. acids from ginkgo biloba exopleura. The effects of pressure, temperature, CO2 mass flow rate, dosage of entrainer and extraction static-dynamic time on the yield of G. acids were investigated in detail, and the central composite design was used to maximize the extraction recovery of G. acids. The amounts of G. acids were analyzed by HPLC with the mixture of methanol and acetic acid solution as the mobile phase. The optimal process parameters for sc-CO2 extraction were determined to be: 31.3MPa extraction pressure, 46.1 oC extraction temperature and 11.1 g min−1 CO2 flow rate, 30mL ethanol entrainer, 1 h extraction static time and 2 h dynamic time. Under the conditions of optical extraction process, the average G. acids extraction rate was 74mg g−1.

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