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        An efficient method to improve the stability of submerged functionally graded cylindrical shell

        Rong Li,Linxia Liu,Bin Liang,Meng Yang 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.6

        An efficient method is presented to improve the stability of a submerged functionally graded (FG) cylindrical shell which is subjected to external hydrostatic pressure. To improve stability while satisfying the application requirements for shell thickness, we focused on the optimum value of the power-law exponent to maximize the critical hydrostatic pressure. The optimum value of the power-law exponent is obtained from an analysis of the influence factors on critical pressure. The results show that the critical pressure can be greatly increased by using the optimum value of the power-law exponent, and the growth rate of critical pressure is almost constant independent of the shell geometry and boundary condition. The advantage of the present method in reducing the shell thickness is illustrated by examples. In addition, the present method is applicable to all kinds of material combinations.

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        Comparative transcriptome analysis in the hepatopancreas of Helice tientsinensis exposed to the toxic metal cadmium

        Zhengfei Wang,Dan Tang,Linxia Sun,Xueling Shi,Ruobing Liu,Huayun Guo,Bo-Ping Tang 한국유전학회 2019 Genes & Genomics Vol.41 No.4

        Background The mudflat crab Helice tientsinensis is one of the most commercially valuable species for crabmeat production due to its delicious taste. These crabs are mainly found in coastal wetland where they are seriously threatened by toxic heavy metal pollution. In crustaceans, the hepatopancreas is an important organ for detoxification, and metal toxic substances can be converted to non-toxic or less toxic compounds in this organ. Objective To develop a better understanding of the molecular response of H. tientsinensis to the toxic metal cadmium (Cd) and provide a molecular basis for the toxic metal tolerance of H. tientsinensis. Methods In this study, we performed comparative hepatopancreas transcriptome analysis between H. tientsinensis unexposed (as control) and exposed to the toxic metal Cd for 48 h. Results We identified 1089 Cd stress significantly-upregulated and 1560 Cd stress significantly-downregulated unigenes. Functional categorization and annotation of these differentially-expressed genes (DEGs) demonstrated that the response to Cd stress in the hepatopancreas of H. tientsinensis mainly involves “antioxidant activity”, “detoxification”, “toxin degradation activity” and “immune system process”. In addition, five genes (ABCC1, NDUFAF5, ASTL, DES1, CYP27A) were identified as possible major targets for toxic metal tolerance. Conclusion This is the first time reporting that the response of H. tientsinensis to Cd exposure at the transcriptome level, and it lays the foundation for understanding the molecular mechanisms of the response of H. tientsinensis to environmental toxic metal stress.

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