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Multi-factor Evolution for Large-scale Multi-objective Cloud Task Scheduling
Tianhao Zhao,Linjie Wu,Di Wu,Jianwei Li,Zhihua Cui 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.4
Scheduling user-submitted cloud tasks to the appropriate virtual machine (VM) in cloud computing is critical for cloud providers. However, as the demand for cloud resources from user tasks continues to grow, current evolutionary algorithms (EAs) cannot satisfy the optimal solution of large-scale cloud task scheduling problems. In this paper, we first construct a large-scale multi-objective cloud task problem considering the time and cost functions. Second, a multi-objective optimization algorithm based on multi-factor optimization (MFO) is proposed to solve the established problem. This algorithm solves by decomposing the large-scale optimization problem into multiple optimization subproblems. This reduces the computational burden of the algorithm. Later, the introduction of the MFO strategy provides the algorithm with a parallel evolutionary paradigm for multiple subpopulations of implicit knowledge transfer. Finally, simulation experiments and comparisons are performed on a large-scale task scheduling test set on the CloudSim platform. Experimental results show that our algorithm can obtain the best scheduling solution while maintaining good results of the objective function compared with other optimization algorithms.
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Zhiwei Jiao,Linjie Zhou,Mengyuan Wu,Kang Gao,Yanlei Su,Zhongyi Jiang 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.12
Inspired by the specific amino acid sequence Asn-Pro-Ala (NPA) of water channel aquaporins (AQPs), we fabricated polyamide (PA) nanofiltration (NF) membranes by introducing reduced glutathione (GSH) in interfacial polymerization (IP) method. Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectrometry (XPS), scanning electron microscope (SEM), atomic force microscopy (AFM), zeta potential and static water contact angle measurement were employed to characterize the chemical composition, morphology, electronegativity and hydrophilicity of the NF membranes. The water flux of GSH/PIP-TMC NF membrane reached 32.00 L m2 h1 at 0.2MPa, which was approximately twice than that of pristine PIP-TMC NF membrane when the ratio of GHS to piperazidine (PIP) was 40% during IP process. More water channels were built as GSH was embedded into PA layer. The fabricated NF membranes also took on potent rejection for dyes and Na2SO4. This study presents a simple and facile method to simulate water channels-based biological materials which may find potential application in water treatment.
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Zhou Wenxian,Shi Yifeng,Wang Hui,Chen Linjie,Yu Caiyu,Zhang Xufei,Yang Lei,Zhang Xiaolei,Wu Aimin 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Intervertebral disc degeneration (IVDD) is a major cause of low back pain (LBP), and excessive senescence and apoptosis of nucleus pulposus (NP) cells are major pathological changes in IVDD. Physical exercise could effectively delay the process of intervertebral disc degeneration; however, its mechanism is still largely unknown. Irisin is an exercise-induced myokine released upon cleavage of the membrane-bound precursor protein fibronectin type III domain-containing protein 5 (FNDC5), and its levels increase after physical exercise. Here, we show that after physical exercise, FNDC5/irisin levels increase in the circulation and NP, senescence and apoptosis are reduced, autophagy is activated in NP tissue, and the progression of IVDD is delayed. Conversely, after knocking out FNDC5, the benefits of physical exercise are compromised. Moreover, the overexpression of FNDC5 in NP tissue effectively alleviated the degeneration of the intervertebral disc (IVD) in rats. By showing that FNDC5/irisin is an important mediator of the beneficial effects of physical exercise in the IVDD model, the study proposes FNDC5/irisin as a novel agent capable of activating autophagy and protecting NP from senescence and apoptosis.
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