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RISS 인기검색어
- 검색키워드
- 저자 : Kuppusamy Baskaran (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
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Kulkarni, Raghavendra Narayanrao,Baskaran, Kuppusamy 한국작물학회 2013 Journal of crop science and biotechnology Vol.16 No.2
An extremely tall mutant (EMS 18-12), a bushy mutant (EMS 24-5), their parental variety Nirmal, and their double mutant recombinant were used to study individual and combined effects of genes producing opposite effects on plant height in periwinkle (Catharanthus roseus). Plant height of the extremely tall mutant (EMS 18-12) was controlled by epistatic inhibitory interaction between two independently inherited dominant genes, Et and H; Et producing extremely tall phenotype and H inhibiting Et. Both genes were inherited independently of plant height-reducing recessive gene by in the bushy mutant (EMS 24-5). Individually, genes Et and by increased and reduced plant height at harvest (when plant were 9 months old) by 90 and 25%, respectively, over parental variety. The double mutant recombinant (Etby) was taller than the bushy mutant (EMS 24-5) and variety, Nirmal but shorter than the extremely tall mutant (EMS 18-12) at different stages. At 1 to 7 weeks after germination, its height was 7.4 to 30.0% greater than the mid-parental value but 5.8 to 30.5% shorter than that expected on the basis of individual effects of genes Et or by. At the age of 4 to 9 months, its height was 5.4 to 40.1% greater than the mid-parental value and 5.6 to 44.1% (except at 5 months) greater than that expected on the basis of individual effects of genes Et or by, suggesting age-dependent epistatic interaction between the genes. No interaction effects were observed for leaf and root yields or contents of alkaloids in leaves and roots.
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Raghavendra Narayanrao Kulkarni,Kuppusamy Baskaran 한국작물학회 2013 Journal of crop science and biotechnology Vol.16 No.2
An extremely tall mutant (EMS 18-12), a bushy mutant (EMS 24-5), their parental variety Nirmal, and their double mutant recombinant were used to study individual and combined effects of genes producing opposite effects on plant height in periwinkle (Catharanthus roseus). Plant height of the extremely tall mutant (EMS 18-12) was controlled by epistatic inhibitory interaction between two independently inherited dominant genes, Et and H; Et producing extremely tall phenotype and H inhibiting Et. Both genes were inherited independently of plant height-reducing recessive gene by in the bushy mutant (EMS 24-5). Individually, genes Et and by increased and reduced plant height at harvest (when plant were 9 months old) by 90 and 25%, respectively, over parental variety. The double mutant recombinant (Etby) was taller than the bushy mutant (EMS 24-5) and variety, Nirmal but shorter than the extremely tall mutant (EMS 18-12) at different stages. At 1 to 7 weeks after germination, its height was 7.4 to 30.0% greater than the mid-parental value but 5.8 to 30.5% shorter than that expected on the basis of individual effects of genes Et or by. At the age of 4 to 9 months, its height was 5.4 to 40.1% greater than the mid-parental value and 5.6 to 44.1% (except at 5 months) greater than that expected on the basis of individual effects of genes Et or by, suggesting age-dependent epistatic interaction between the genes. No interaction effects were observed for leaf and root yields or contents of alkaloids in leaves and roots
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Vanitha, Manickam Kalappan,Priya, Kalpana Deepa,Baskaran, Kuppusamy,Periyasamy, Kuppusamy,Saravanan, Dhravidamani,Venkateswari, Ramachandran,Mani, Balasundaram Revathi,Ilakkia, Aruldass,Selvaraj, Sund KOREAN PHARMACOPUNCTURE INSTITUTE 2015 Journal of pharmacopuncture Vol.18 No.3
Objectives: The present study was undertaken to determine the modulatory effect of taurine on the liver mitochondrial enzyme system with reference to mitochondrial lipid peroxidation (LPO), antioxidants, major tricarboxylic acid cycle enzymes, and electron transport chain enzymes during 7,12-dimethyl benz[a]anthracene (DMBA) induced breast cancer in Sprague-Dawley rats. Methods: Animals in which breast cancer had been induced by using DMBA (25 mg/kg body weight) showed an increase in mitochondrial LPO together with decreases in enzymic antioxidants (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR) and glutathione-S-transferase (GST)), non-enzymic antioxidants (reduced glutathione (GSH), vitamin C, and vitamin E), in citric acid cycle enzymes (isocitrate dehydrogenase (ICDH), alpha ketoglutarate dehydrogenase (alpha KDH), succinate dehydrogenase (SDH) and malate dehydrogenase (MDH)), and in electron transport chain (ETC) complexes. Results: Taurine (100 mg/kg body weight) treatment decreased liver mitochondrial LPO and augmented the activities/levels of enzymic, and non-enzymic antioxidants, tricarboxylic acid cycle enzymes and ETC complexes. Conclusion: The results of our present study demonstrated the chemotherapeutic efficacy of taurine treatment for DMBA-induced breast carcinomas.
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Manickam Kalappan Vanitha,Kalpana Deepa Priya,Kuppusamy Baskaran,Kuppusamy Periyasamy,Dhravidamani Saravanan,Ramachandran Venkateswari,Balasundaram Revathi Mani,Aruldass Ilakkia,Sundaramoorthy Selvara 대한약침학회 2015 Journal of pharmacopuncture Vol.18 No.3
Objectives: The present study was undertaken to determine the modulatory effect of taurine on the liver mitochondrial enzyme system with reference to mitochondrial lipid peroxidation (LPO), antioxidants, major tricarboxylic acid cycle enzymes, and electron transport chain enzymes during 7,12-dimethyl benz[a]anthracene (DMBA) induced breast cancer in Sprague-Dawley rats. Methods: Animals in which breast cancer had been induced by using DMBA (25 mg/kg body weight) showed an increase in mitochondrial LPO together with decreases in enzymic antioxidants (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR) and glutathione-S-transferase (GST)), non-enzymic antioxidants (reduced glutathione (GSH), vitamin C, and vitamin E), in citric acid cycle enzymes (isocitrate dehydrogenase (ICDH), alpha ketoglutarate dehydrogenase (alpha KDH), succinate dehydrogenase (SDH) and malate dehydrogenase (MDH)), and in electron transport chain (ETC) complexes. Results: Taurine (100 mg/kg body weight) treatment decreased liver mitochondrial LPO and augmented the activities/levels of enzymic, and non-enzymic antioxidants, tricarboxylic acid cycle enzymes and ETC complexes. Conclusion: The results of our present study demonstrated the chemotherapeutic efficacy of taurine treatment for DMBA-induced breast carcinomas.
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