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전영은 ( Young Eun Jeon ),윤명근 ( Myoung Kun Yoon ),김성주 ( Sung Joo Kim ),장봉림 ( Pong Rheem Jang ),강정배 ( Jung Bae Kang ),박영한 ( Young Han Park1 ),임채춘 ( Chae Chun Rhim ),민수기 ( Soo Kee Min ) 대한주산의학회 2006 Perinatology Vol.17 No.1
Uterine arteriovenous malformations are very rare but potentially life threatening lesions. These lesions may be congenital or acquired, but especially occur in patients with a history of curettage, abortion or pregnancy. Color doppler ultrasonography is the preferred method of diagnosing of arteriovenous malformations. In many cases, hysterectomies are performed. But if patients want pregnancies, embolization therapy and conservative treatment are effective therapy. We have experienced a clinical case of uterine arteriovenous malformation, which is presented with a brief review of literature.
An ISFET biosensor for the monitoring of maltose-induced conformational changes in MBP
Park, Hye-Jung,Kim, Sang Kyu,Park, Kyoungsook,Lyu, Hong-Kun,Lee, Chang-Soo,Chung, Sang J.,Yun, Wan Soo,Kim, Moonil,Chung, Bong Hyun Elsevier 2009 FEBS letters Vol.583 No.1
<P><B>Abstract</B></P><P>Here we describe an ion sensitive field effect transistor (ISFET) biosensor, which was designed to monitor directly the surface charge of structurally altered maltose binding protein (MBP) upon stimulation with maltose. This study is the first report of the application of a FET biosensor to the monitoring of conformationally changed proteins. Consequently, a significant drop in current on the basis of the charge-dependent capacitance measurement has been clearly observed in response to maltose, but not for the glucose control, thereby indicating that the substrate-specific conformational properties of the target protein could be successfully monitored using the ISFET. Collectively, our results clearly suggest that ISFET provide a high fidelity system for the detection of maltose-induced structural alterations in MBP.</P>
Brain abscess due to odontogenic infection: a case report
Sung Yong Park,Dong Won Suh,Chul Min Park,Min Seok Oh,Dong-Kun Lee 대한구강악안면외과학회 2014 대한구강악안면외과학회지 Vol.40 No.3
In this report, we describe a case of brain abscess due to odontogenic infection. A 53-year-old female who had been suffering from headache and trismus for two weeks visited the Department of Oral and Maxillofacial Surgery at the Sun Dental Hospital (Daejeon, Korea). Even after several routine tests, we still could not make a diagnosis. However, after the combined multidisciplinary efforts of oral surgeons and neurosurgeons, the patient was treated for odontogenic infection and made an uneventful recovery. Therefore, patients with infections in the head and neck region showing symptoms such as headache, changes in mental state, nausea, vomiting, seizures, hemiplegia, speech disturbance, and visual disturbance, a brain abscess should be included in the list of differential diagnoses.
A follow-up study on extracorporeal fixation of condylar fractures using vertical ramus osteotomy
Sung Yong Park,Jae Hyoung Im,Seong Hoe Yoon,Dong Kun Lee 대한구강악안면외과학회 2014 대한구강악안면외과학회지 Vol.40 No.2
Objectives: The aim of this study is to report the results of extracorporeal fixation in patients with mandibular condylar fractures and compare them with the clinical results of conservative treatment. Materials and Methods: The medical records of 92 patients (73 male [M] : 19 female [F], age 13-69 years, mean 33.1 years) treated for condylar fractures at the Department of Oral and Maxillofacial Surgery in Sun Dental Hospital (Daejeon, Korea) from 2007 to 2012 were reviewed. Patients were divided into three groups: group A (23 patients; M : F=18 : 5, age 21-69 years, mean 32.6 years), treated with extracorporeal fixation; group B (30 patients; M : F=24 : 6, age 16-57 years, mean 21.1 years), treated by conventional open reduction; and group C (39 patients; M : F=31 : 8, age 16-63 years, mean 34.4 years), treated with the conservative method (‘closed’ reduction). Clinical and radiographic findings were evaluated and analyzed statistically. Results: Occurrence of postoperative condylar resorption correlated with certain locations and types of fracture. In this study, patients in group A (treated with extracorporeal fixation) did not demonstrate significant postoperative complications such as malocclusion, mandibular hypomobility, temporomandibular disorder, or complete resorption of condyle fragments. Conclusion: In superiorly located mandibular condyle fractures, exact reconstruction of condylar structure with the conventional open reduction technique can be difficult due to the limited surgical and visual fields. In such cases, extracorporeal fixation of the condyle using vertical ramus osteotomy may be a better choice of treatment because it results in anatomically accurate reconstruction and low risk of complications.
Analysis of the mode of inheritance in Chrysanthemum morifolium Ramat. using SSR markers
Sang Kun Park,Hak Ki Shin,Danny Esselink,Paul Arens 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07
Most of cultivated chrysanthemums (Chrysanthemum morifolium Ramat.) have been found to be polyaneuploid with hexaploid, 2n=6x=54, predominant. Cytological studies has shown that bivalent were normally formed and multivalent were rare during meiosis. These meiotic behavior reflected that the chromosome of chrysanthemum paired with its homologue preferentially and diploid-like inheritance was occurring. However, several genetic researches was in contrast to this hypothesis, based on the results of genetic analysis. Therefore, it is important to determine whether the mode of inheritance in chrysanthemum is disomic (selective pairing) or hexasomic (random pairing). ‘Dancer’ and ‘Puma White’, and their 94 crossing progenies were genotyped using 84 SSR primers. Alleles of each SSR locus were determined by length of PCR product with fluorescently labeled primers using ABI 3730 DNA Analyzer and GeneMapper 3.0 software (Applied Biosystems). A total of 210 types of alleles were detected in 49 SSR loci (4.29 allele types/locus). The observed segregation ratio of these alleles for 94 crossing progenies showed better fits to hexasomic than disomic. Moreover, based on the genotyping results, the genotypes of ‘Dancer’ and ‘Puma White’ were analyzed as BCDEFF and AACEEE in ChSSR-61 locus, respectively. And the genotypes of PD-33 and PD-51 were analyzed as ABDEEF and ABDEEF, respectively. It means that BDF alleles of PD-33 and BEE alleles of PD-51 were given from ‘Dancer’. If the chromosome is paired preferentially, the B allele would pair with C allele, D with E, and F with E at this locus of ‘Dancer’. But it was found PD-75 as AADEEF without B and C alleles. This is a clear evidence that the mode of inheritance in chrysanthemum is not disomic but hexasomic.