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- 저자 : Krishna Kumar Jaiswal (검색결과 2 건)
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Krishna Kumar Jaiswal,Ishita Banerjee,Swapnamoy Dutta,Ravikant Verma,Lokanadhan Gunti,Sharad Awasthi,Mayank Bhushan,Vinod Kumar,Mohamed Fahad Alajmi,Afzal Hussain 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.107 No.-
The rapid emergence of multidrug-resistant microbes has turned into the main threat to public healthworldwide. The preparation and application of nanomaterial-based antimicrobials have increased toaddress this problem with great significance. This study has investigated the bio-fabrication of polycrystallineAg-NCs using BCE as a reducer and stabilizer under microwave irradiation. Ag-NCs formationswere optimized using varying concentrations of BCE and silver acetate. The XRD confirmed the incidenceof phases of nanostructured crystals of Ag/AgO/AgCl. The average crystallite sizes were calculated to be22.19, 36.65, and 36.65 nm for Ag, AgO, and AgCl, respectively. SERS spectra revealed the vibrationalmodes of the Ag and Ag-O stretch bands. FTIR spectra have indicated the incidence of chemical fingerprintsfor Ag-NCs and BCE biomolecules. SEM and HR-TEM micrographs exhibited the almost sphericalto the oval shape of 50 nm. SAED pattern attested to silver crystallinity in agreement with XRD analysis. The MIC values of the Ag-NCs against Escherichia coli, Staphylococcus aureus, Aspergillus brasiliensis, andRhizopus stolonifer were observed to be 120, 60, 200, and 100 mg/ml, respectively. This study has demonstratedthe facile method to prepare polycrystalline Ag-NCs with appropriate structural and morphologicalcharacteristics for antimicrobial applications.
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Kamlesh Rangari,Kuntal Kanti Das,Suyash Singh,Krishna G. Kumar,Kamlesh Singh Bhaisora,Jayesh Sardhara,Anant Mehrotra,Arun Kumar Srivastava,Awadhesh Kumar Jaiswal,Sanjay Behari 대한척추신경외과학회 2021 Neurospine Vol.18 No.1
Objective: Posterior fossa decompression is the treatment of choice in type 1 Chiari malformation (CM-1) without bony instability. Although surgical fixation has been recommended by a few authors recently, comparative studies to evaluate these treatment strategies using objective outcome tools are lacking. Methods: Seventy-three patients with pure CM-1 (posterior fossa bony decompression [PFBD], n=21; posterior fossa bony and dural decompression [PFBDD], n=40; and posterior fixation [PF], n=12) underwent a postoperative outcome assessment using Chicago Chiari Outcome Score (CCOS). Logistic regression analysis detected predictors of an unfavorable outcome. Results: Minimally symptomatic patients generally underwent a PFBD while most of the clinically severe patients underwent a PFBDD (p=0.049). The mean CCOS score at discharge was highest in the PF (12.0±1.41) and lowest in PFBDD group (10.98±1.73, p=0.087). Patients with minimal preoperative clinical disease severity (adjusted odds ratio [AOR], 4.58; 95% confidence interval [CI], 1.29–16.31) and PFBDD (AOR, 7.56; 95% CI, 1.70–33.68) represented risks for an unfavorable short-term postoperative outcome. Though long-term outcomes (CCOS) did not differ among the 3 groups (p=0.615), PFBD group showed the best long-term improvements (mean follow-up CCOS, 13.71±0.95), PFBDD group improved to a comparable degree despite a poorer short-term outcome while PF had the lowest scores. Late deteriorations (n=3, 4.1%) occurred in the PFBDD group. Conclusion: Minimally symptomatic patients and PFBDD predict a poor short-term postoperative outcome. PFBD appears to be a durable procedure while PFBDD group is marred by complications and late deteriorations. PF does not provide any better results than posterior fossa decompression alone in the long run.
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