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Thanisa Tongbai,Shaunagh McDermott,Nantaka Kiranantawat,Victorine Vining Muse,Carol Chia-chia Wu,Jo-Anne O’Malley Shepard,Matthew David Gilman 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.11
Objective: To investigate the predictive factors for a non-diagnostic result and the final diagnosis of pulmonary lesions with an initial non-diagnostic result on CT-guided percutaneous transthoracic needle biopsy. Materials and Methods: All percutaneous transthoracic needle biopsies performed over a 4-year period were retrospectively reviewed. The initial pathological results were classified into three categories—malignant, benign, and non-diagnostic. A non-diagnostic result was defined when no malignant cells were seen and a specific benign diagnosis could not be made. The demographic data of patients, lesions’ characteristics, technique, complications, initial pathological results, and final diagnosis were reviewed. Statistical analysis was performed using binary logistic regression. Results: Of 894 biopsies in 861 patients (male:female, 398:463; mean age 67, range 18–92 years), 690 (77.2%) were positive for malignancy, 55 (6.2%) were specific benign, and 149 (16.7%) were non-diagnostic. Of the 149 non-diagnostic biopsies, excluding 27 cases in which the final diagnosis could not be confirmed, 36% revealed malignant lesions and 64% revealed benign lesions. Predictive factors for a non-diagnostic biopsy included the size ≤ 15 mm, needle tract traversing emphysematous lung parenchyma, introducer needle outside the lesion, procedure time > 60 minutes, and presence of alveolar hemorrhage. Non-diagnostic biopsies with a history of malignancy or atypical cells on pathology were more likely to be malignant (p = 0.043 and p = 0.001). Conclusion: The predictive factors for a non-diagnostic biopsy were lesion size ≤ 15 mm, needle tract traversing emphysema, introducer needle outside the lesion, procedure time > 60 minutes, and presence of alveolar hemorrhage. Thirty-six percent of the non-diagnostic biopsies yielded a malignant diagnosis. In cases with a history of malignancy or the presence of atypical cells in the biopsy sample, a repeat biopsy or surgical intervention should be considered.
Potential Use of Transferred Lymph Nodes as Metastasis Detectors after Tumor Excision
Nicoli, Fabio,Ciudad, Pedro,Lim, Seong Yoon,Lazzeri, Davide,D'Ambrosia, Christopher,Kiranantawat, Kidakorn,Chilgar, Ram M,Sapountzis, Stamatis,Sacak, Bulent,Chen, Hung-Chi Korean Society of Plastic and Reconstructive Surge 2015 Archives of Plastic Surgery Vol.42 No.4
Due to the fact that it reliably results in positive outcomes, lymph node flap transfer is becoming an increasingly popular surgical procedure for the prevention and treatment of lymphedema. This technique has been shown to stimulate lymphoangiogenesis and restore lymphatic function, as well as decreasing infection rates, minimizing pain, and preventing the recurrence of lymphedema. In this article, we investigate possible additional benefits of lymph node flap transfer, primarily the possibility that sentinel lymph nodes may be used to detect micrometastasis or in-transit metastasis and may function as an additional lymphatic station after the excision of advanced skin cancer.
Potential Use of Transferred Lymph Nodes as Metastasis Detectors after Tumor Excision
Fabio Nicoli,Pedro Ciudad,Seong Yoon Lim,Davide Lazzeri,Christopher D’Ambrosia,Kidakorn Kiranantawat,Ram M. Chilgar,Stamatis Sapountzis,Bulent Sacak,Hung-Chi Chen 대한성형외과학회 2015 Archives of Plastic Surgery Vol.42 No.4
Due to the fact that it reliably results in positive outcomes, lymph node flap transfer is becoming an increasingly popular surgical procedure for the prevention and treatment of lymphedema. This technique has been shown to stimulate lymphoangiogenesis and restore lymphatic function, as well as decreasing infection rates, minimizing pain, and preventing the recurrence of lymphedema. In this article, we investigate possible additional benefits of lymph node flap transfer, primarily the possibility that sentinel lymph nodes may be used to detect micrometastasis or in-transit metastasis and may function as an additional lymphatic station after the excision of advanced skin cancer.