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Association Between Age and Sleep Quality: Findings From a Community Health Survey
Kim Minjung,Um Yoo Hyun,Kim Tae Won,Kim Sung-Min,Seo Ho-Jun,Jeong Jong-Hyun,Lee Jihyung,Kim Suhyung,Cho In Hee,김석영,Hong Seung-Chul 대한수면학회 2021 sleep medicine research Vol.12 No.2
Background and Objective This study aimed to investigate the changes in sleep quality with increasing age and the effect of age on the components of the Pittsburgh Sleep Quality Index (PSQI).Methods We used data from the Community Health Survey conducted by the Korea Center for Disease Control and Prevention in 2018. A total of 228340 participants in this nationwide survey. Sleep quality was assessed using the PSQI. Adults aged ≥ 19 years were divided into six age groups and one-way analysis of variance (one-way ANOVA) was used to compare the mean values of PSQI of each group. By comparing the scores for each PSQI component in those aged ≥ 65 years and < 65 years, we aimed to reveal the differences in special components according to age group.Results In total, 223334 respondents were included in the study. Based on a one-way ANOVA, the PSQI score generally increased with age. Although the average PSQI score of patients in their 40s was lower than that of patients in their 30s, there was no significant difference between the two groups (p = 0.11). When the PSQI component was compared between the population aged over and under 65 years, the population aged ≥ 65 years scored higher in most components. In contrast, daytime dysfunction scored higher in the population aged < 65 years.Conclusions Sleep quality tends to decrease with increasing age. Several factors, including physiological changes, underlying physical conditions, and psychosocial factors, may contribute to a decrease in sleep quality with age.
Kim, Kangmin,Park, Suhyung,Park, Jeong Hwan,Cho, Won-Sang,Kim, Hyoun-Ee,Lee, Sung-Mi,Kim, Jeong Eun,Kang, Hyun-Seung,Jang, Tae-Sik The Korean Neurosurgical Society 2021 Journal of Korean neurosurgical society Vol.64 No.6
Objective : Biodegradable poly-L-lactic acid (PLLA) with a highly biocompatible surface via tantalum (Ta) ion implantation can be an innovative solution for the problems associated with current biodegradable stents. The purpose of this study is to develop a Taimplanted PLLA stent for clinical use and to investigate its biological performance capabilities. Methods : A series of in vitro and in vivo tests were used to assess the biological performance of bare and Ta-implanted PLLA stents. The re-endothelialization ability and thrombogenicity were examined through in vitro endothelial cell and platelet adhesion tests. An in vivo swine model was used to evaluate the effects of Ta ion implantation on subacute restenosis and thrombosis. Angiographic and histologic evaluations were conducted at one, two and three months post-treatment. Results : The Ta-implanted PLLA stent was successfully fabricated, exhibiting a smooth surface morphology and modified layer integration. After Ta ion implantation, the surface properties were more favorable for rapid endothelialization and for less platelet attachment compared to the bare PLLA stent. In an in vivo animal test, follow-up angiography showed no evidence of in-stent stenosis in either group. In a microscopic histologic examination, luminal thrombus formation was significantly suppressed in the Ta-implanted PLLA stent group according to the 2-month follow-up assessment (21.2% vs. 63.9%, p=0.005). Cells positive for CD 68, a marker for the monocyte lineage, were less frequently identified around the Ta-implanted PLLA stent in the 1-month follow-up assessments. Conclusion : The use of a Ta-implanted PLLA stent appears to promote re-endothelialization and anti-thrombogenicity.
Fundamental Groups of 3-dimensional Infra-Nilmanifolds
Kim, Suhyung 단국대학교 통계문제연구소 1991 數學 및 統計硏究 Vol.19 No.-
The problem of the classification of 3-dimensional infra-nilmanifolds has a close relation with their fundamental groups, called almost Bieberbach groups. In fact, infra-nilmanifolds are determined uniquely by the fundamental groups π, as in the case of a compact flat Riemannian manifold. It is well-known that two infra-nilmanifolds are affinely diffeomorphic if and only if the fundamental groups are isomorphic. We will show that an almost Bieberbach group is characterized as a torsion-free, virtually nilpotent group of rank 3. It turns out that such a group π is of the form 1→Z→πQ→1 Where Q is a 2-dimensional crystallographic group. There are 17 crystallographic groups in dimension 2. However, we shall obtain torsion-free extensions only from 7 groups. First we recall the necessary terminology.
Suhyung Kim,Jong-Hyun Jeong,Yoo Hyun Um,Tae-Won Kim,Ho-jun Seo,Seung-Chul Hong 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.4
Objective: Antipsychotic drugs are known as the major cause of non-neoplastic hyperprolactinemia. This study aimed to investigate the levels of serum prolactin depending on the use of antipsychotic drugs in patients through the Clinical Data Warehouse (CDW). Methods: We conducted a cohort search in the CDW application and got 260 patients’ medical records diagnosed with schizophrenia, schizotypal and delusional disorders, manic episodes, and bipolar affective disorders who were taking one of risperidone, blonanserin, amisulpride, and olanzapine. After that, we reviewed the medical data and used the ANCOVA analysis and the post hoc test to compare serum prolactin levels among four antipsychotic drug groups. Results: Among the 117 subjects included in the analysis, the mean serum prolactin level was 64.6 ± 54.6 ng/ml. Serum prolactin levels were significantly higher in subjects taking risperidone or amisulpride compared to blonanserin and olanzapine. The female subjects who took blonanserin, olanzapine, and risperidone had significantly higher prolactin levels, but there was no difference in serum prolactin levels between sex in the subjects who took amisulpride. Conclusion: This study suggests the need for regular monitoring of serum prolactin levels in patients who are taking antipsychotics, especially in female patients. And we showed that there is a possibility to conduct more effective and simpler big data research using the CDW. Further studies on the subjects with controlled confounding variables and larger sample groups are needed.
디젤차량의 난방성능 향상을 위한 보조난방장치 적용에 관한 연구
김수형(Suhyung Kim),나원균(Weonkyun Na) 한국자동차공학회 2004 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
Recently-increasing demands for diesel engine in the market make an auxiliary heater essential in a passenger car because the fuel-efficient diesel does not dissipate enough heat to coolant to warm up the passenger compartment with a single conventional heater at the cold start. This study introdued the principle and structure of the fuel fired, plug and PTC heater. And the heating performances of these auxiliary heaters were compared and analyzed.
Current Challenges in Bacterial Transcriptomics
Cho, Suhyung,Cho, Yoobok,Lee, Sooin,Kim, Jayoung,Yum, Hyeji,Kim, Sun Chang,Cho, Byung-Kwan Korea Genome Organization 2013 Genomics & informatics Vol.11 No.2
Over the past decade or so, dramatic developments in our ability to experimentally determine the content and function of genomes have taken place. In particular, next-generation sequencing technologies are now inspiring a new understanding of bacterial transcriptomes on a global scale. In bacterial cells, whole-transcriptome studies have not received attention, owing to the general view that bacterial genomes are simple. However, several recent RNA sequencing results are revealing unexpected levels of complexity in bacterial transcriptomes, indicating that the transcribed regions of genomes are much larger and complex than previously anticipated. In particular, these data show a wide array of small RNAs, antisense RNAs, and alternative transcripts. Here, we review how current transcriptomics are now revolutionizing our understanding of the complexity and regulation of bacterial transcriptomes.