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      • SPIM 벡터제어를 위한 태양광 발전 시스템

        고재섭(Jae-Sub Ko),최정식(Jung-Sik Choi),정병진(Byung-Jin Jung),김도연(Do-Yeon Kim),박기태(Ki-Tae Park),최정훈(Jung-Hoon Choi),정동화(Dong-Hwa Chung) 한국조명·전기설비학회 2007 한국조명·전기설비학회 학술대회논문집 Vol.2007 No.11월

        This paper presents the photovoltaic(PV) water pumping system with a maximum power point tracking(MPPT). The water pumping system uses a variable speed single phase induction motor(SPIM) driven a centrifugal pump by field oriented control(FOC) inverter. The MPPT using a DC-DC converter controlled the duty cycle to track maximum power from PV under different insolation conditions. The duty cycle directly relate with a flux producing current control(i<SUB>ds</SUB>). The FOC inverter uses a current control voltage source inverter(CC-VSI). The simulation results are shown that the characteristics and performance of drive system, which varies as each conditions of light by expresses in voltage(V<SUB>dq</SUB>), current(I<SUB>dq</SUB>), speed of motor and torque.

      • SCISCIESCOPUS

        Expression of Wnt Target Genes in Solid Pseudopapillary Tumor of the Pancreas: A Pilot Study

        Kang, Chang Moo,Kim, Hyun Ki,Kim, Hoguen,Choi, Gi Hong,Kim, Kyung Sik,Choi, Jin Sub,Lee, Woo Jung Lippincott Williams Wilkins, Inc. 2009 PANCREAS Vol.38 No.2

        OBJECTIVES:: Solid pseudopapillary tumor (SPT) of the pancreas is very rare. This study was performed to analyze the expression of Wnt signal target genes (matrix metalloproteinase-7 [MMP-7], cyclin-D1, and c-myc) and Ki-67 in resected SPTs to determine their clinicopathologic characteristics according to their expression. METHODS:: From January 1995 to December 2005, 23 patients underwent pancreatic resections for SPT of the pancreas. Among 23 formalin-fixed, paraffin-embedded tissues, 12 were evaluated as a pilot study. Immunohistochemistry was performed using various detection and antigen retrieval methods to detect MMP-7, cyclin-D1, c-myc, and Ki-67. The expression of Wnt target genes was correlated with clinicopathologic features of the patients. RESULTS:: Solid pseudopapillary tumors of the pancreas always showed cytoplasmic/nuclear accumulation of &bgr;-catenin, frequent expression of cyclin-D1, and low proliferation index. MMP-7, cyclin-D1, c-myc, and Ki-67 were not correlated with microscopic features suggesting malignant potential (P > 0.05). Tumor size was closely related to microscopic features of malignant potential and apparently has an inverse relationship with the expression of cyclin-D1 and Ki-67 (P < 0.05). CONCLUSIONS:: Low proliferative index and associated MMP-7 expression may cause an unpredictable clinical course in this tumor. Subtle changes in the intracellular environment, not pathologic (morphologic) changes, may elucidate the unpredictable clinical course of this tumor.

      • 신이식에서 이식신의 생존분석

        오선미,김종학,황평주,구영선,강민규,나기량,김종섭,김성숙,이강욱,신영태,설종구,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

        To investigate the prognostic factors for the survival of transplanted kidney in patients with end-stage renal failure, 59 cases of renal transplantation from September 1986 to Feburary 1997 in Chungnam National University Hospital were analyzed retrospectively. The results were as follows: 1)The mean age of recipients was 33.8 years and that of doners was 38.9 years. The male to female ratio of recipients was 2.5:1, and that of donors was 1.03:1 2) Living related donore(LRD) were 79.6% and living non-related donors were 20.3%. The HLA-identical donors(ID) in LRD were 18.7% and HLA-haploidentical donors(HID) were 61.0%. In living non-related donors(LNRD), mean matched HLA-AB antigens were 1.56 and mean matched HLA-DR antigens were 0.56. 3) The average 5-year patient survival fate was 94%, and average 5-year graft survival rate was 70%. The 5-year graft survival fate of HLA-ID was 100%, and those HLA-HID and LNR were 70% and 36% respectively. 4) Total 33 episodes of acute rejection were found in 45.8% of transplanted patients. The number of acute rejection episode did not show significant difference between LRD and LNRD(P > 0.05). There was no significant difference in MLC between two groups(p > 0.05). 5) In comparison between the 18 patients who lost their graft function in 5 years and 17 patients who are maintaining graft function for more than 5 years, MLC was significantly lower in patients with functioning graft than of patients with non-functioning graft (p < 0.05). The number of rejection episode was also lower in patients with functioning graft than that of the patients with non-functioning graft(p < 0.05). However, there were no significant difference in recepient and donor age and history of pre-transplantation donor specific transfusion between two groups. With the results above, we can speculate that adequate donor selection according to good matched HLA typing and low MLC is very important for graft survival in renal transplantation. Prevention and treatment of acute rejection in renal transplantation is also na important factor for graft survival.

      • IPMSM 드라이브의 최대토크를 위한 적응 FNN 제어기

        김도연(Do-Yeon Kim),고재섭(Jae-Sub Ko),최정식(Jung-Sik Choi),정병진(Byung-Jin Jung),박기태(Ki-Tae Park),최정훈(Jung-Hoon Choi),정동화(Dong-Hwa Chung) 한국조명·전기설비학회 2007 한국조명·전기설비학회 학술대회논문집 Vol.2007 No.11월

        Interior permanent magnet synchronous motor(IPMSM) has become a popular choice in electric vehicle applications, due to their excellent power to weight ratio. This paper proposes maximum torque control of IPMSM drive using adaptive fuzzy neural network controller and artificial neural network(ANN). This control method is applicable over the entire speed range which considered the limits of the inverter's current and voltage rated value. For each control mode, a condition that determines the optimal d-axis current i<SUB>d</SUB> for maximum torque operation is derived. This paper considers the design and implementation of novel technique of high performance speed control for IPMSM using Adaptive-FNN controller and ANN controller. The hybrid combination of neural network and fuzzy control will produce a powerful representation flexibility and numerical processing capability. Also, this paper proposes speed control of IPMSM using Adaptive-FNN and estimation of speed using ANN controller. The back propagation neural network technique is used to provide a real time adaptive estimation of the motor speed. The proposed control algorithm is applied to IPMSM drive system controlled Adaptive-FNN and ANN controller, the operating characteristics controlled by maximum torque control are examined in detail. Also, this paper proposes the analysis results to verify the effectiveness of the Adaptive-FNN and ANN controller.

      • 외과 영역에 있어서 Venoplant^(R)의 임상적 고찰

        김재호,노승무,장일성,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

        The clinical effects of Venoplant^(R) was observed in 30 cases with conditions that a surgical management has been taken. Venoplant^(R) was administered via intravenous root with 2 to 5 ml, 2 to 4 times per one day for postoperatively 3 to 7 days. An overall effectiveness rate was 66.6% and mild nausea was observed in one case. In conclusion, Venoplant^(R) was effective in the edema, pain, and redness on the wound.

      • 외과적 복부 감염증에 대한 세균학적 연구

        金亨洙,孫基燮 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.1

        One hundred and fourteen patients with surgical infection were studied. 65 patients of these had intraabdominal abscess, and the remainders had wound infection. The patients surveyed were admitted at the department of general surgery in Chungnam National University Hospital during the period from April 1981 to March 1984. The author has analyzed clinically the cases with respects of age, sex, primary diseases and has investigated the causative agents of surgical infection, and also studied drug resistance of isolated strains to the various antibiotics by antibiotic susceptibility test. The results were summarized as follows: 1. In the distribution of age, the fifties and sixties (48.2%) were two times as many as the thirties and forties (28.1%). The prevalence rates were 43.0% in summer and 14.9% in winter. 2. The commonest primary disease in intraabdominal abscess and wound infection was perforated appendicitis and periappendiceal abscess (36.9% and 35.7%, respectively). 3. Positive culture were obtained in 84.2% of 114 patients. Of these, intraabdominal abscess was 89.2% and wound infection was 77.6%. Aerobes isolated were 63.5%, aerobes and anaerobes isolated concomitantly were 29.2%, and anaerobes isolated were 7. 3%. 4. Total 193 strains were isolated from patients with surgical infection. Of these, aerobes were 72.6% and anaerobes were 27.4%. The commonest organism was Escherichia coli as 36.9%, the next was Bacteroides as 18.5%, the others isolated were Klebsiella as 11.3%, and Proteus as 10.1%, etc. 5. E. coli was 48.1% of isolated aerobes and Bacteroides fragilis was 50.0% of isolated anaerobes 6. Isolated strains of E. coli and Bacteroides fragilis from patients with surgical infection were resistant to the most of antibiotics such as erythromycin, kanamycin, lincomycin, neomycin, penicillin and tetracycline, but sensitive to chloramphenicol and cephalothin. As above results, E. coli and Bacteroides fragilis were most commonly isolated from patients with surgical infection of the abdomen, and most of isolated strains were resistant to various antibiotics. Therefore, the treatment of surgical infection requires not only proper surgical managements but also appropriate antibacterial therapy by the results of antibiotic susceptibility test.

      • 중증 세균 감염 및 내성균에 대한 Fosfomycin의 치료효과

        김찬기,노승무,윤완희,장일성,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

        A Clinical study for the therapeutic effect of Fosfomycin was made in 20 cases with the severe infection and the resistent organisms against the other antibiotics. Fosfomycin was administered intravenously 2-4 gm daily in two divided for an average of 13.1 days. The overall effectiveness was 90% without any significant side effect and the effectiveness for the resistant organisms(13 cases) against the other antibiotics was 84.6%. These results demonstrated that Fosfomycin can be used effectively in the treatment of the severe infection and the resistant organisms against the other antibiotics.

      • 急ㆍ慢性 膽囊炎 患者의 膽囊內膽汁의 細菌學的 硏究

        金五經,孫基燮 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.1

        In general, acute and chronic cholecystitis, the pathogenesis is still not completely understood, seems to be related to four factors, obstruction, ischemia, chemical injury and bacterial invasion due to chiefly biliary stones (90-95%), and serous systemic disorders, major injuries (trauma and operation), congenital abnormalities and other bad physical conditions³). Above all the presense of organisms are responsible nat noly for the development of acute cholecystitis but also for the postoperative complications and mortality^5). About 5 per cent (about 20 per cent in the United States)^1), of surgical patient have been entered in this hospital for surgery of the biliary tract because of acute and chronic cholecystitis. In spite of that microorganisms in the biliary tract has recently not been studied in this country as well as other countries^6). The purpose of this investigation was to asses the incidence of organisms from the gallbladder bile of the patients with acute and chronic cholecystitis by utilization of standardized methods of aerobic and anaerobic cultures. Seventy eight consecutive patients with acute and chronic cholecystitis underwent cholecystectomy during the two years and nine months between january 1981 and september 1983 were studied and also correlate the presence of bateria cultured from gallbladder bile with leukocytes and several items of important liver function test. Ten consecutive with other diseases has been utilized as control group. The results are summarised as follows. 1. Of these 88 patients, 42 patents (54%) are female and 36 patients (46) are male. 2. Reference to the table reveals that 6 of the 47 gallbladder bile, or 12. 8 per cent, were cultured anaerobic organisms and 61 of the 78 gallblader bile, or 78.2 per cent were cultured aerobically 3. Of 10 gallbladder bile, control group, one had positive culture which revealed Escherichia 4. The organisms obtained from anaerobic cultures were two cases of Bacteroides fragilis 33.3%, two cases of Fusobactrium symbiosum, a Bacteroides asaccharolyticus and a Clostrium gtridiforme (16.7%), respectively. 5. The oganisms obtained from aerobic cultures were 32 cases (45. 1%) of Escherihia coli, 19 case (26.8%) of Klebsiella species, 6 cases (8.5%) of Enterobacter species, 5 cases (7. 1%) of proteus species, 3 cases (4.2%) of Citrobacter species, 2 cases (2.8%) of Salmonella typhi and the others were one of Providencia rettgeri, Aeromonas hydrophilia, Acinetobacter calcoaceticus, taphylococcus aureus, respectively. 6. The mean value of leukocytes of aerobic group was 12.461/mm³obvious difference compared to control group which was statistically significant with a p<0.05. 7. Both mean value of SGPT, SGPT and albumin of anaerobic group were P<0.05, respectively, d SGOT and albumin of aerobic group were a p<0.01, respectively, and total bilirubin was a P<0.05 those were statistically significant value.

      • 다층구조를 갖는 다공질규소층의 제작과 이의 물성

        김영유,전종현,류성주,이영섭,이기원,최봉수 대전산업대학교 반도체기술연구소 2000 半導體技術硏究所報 Vol.2 No.-

        단결정규소 웨이퍼를 15% HF에탄올 용액에서 양극 산화시켜 다공질규소를 얻는 과정에서 전류밀도와 에칭시간에 따라 굴절률이 주기적으로 변하는 다충의 다공질규소층(porous silicon multilayers)을 구현하였다. 그리고 다층의 다공질규소층(Ⅰ) 다공질규소 발광충, 또 다른 다층의 다공질규소층(Ⅱ)의 순으로 구성된 porous silicon microcavity(PSM)를 제작하고 그 물성을 조사하였다. PSM 상하에 위치한 다층의 다공질규소층의 단면을 AFM(Atomic Force Microscope)으로 조사한 결과 고굴절률과 저굴절률이 주기적으로 교차하는 층이 균일하게 형성되었으며, 중앙의 다공질규소 발광층도 균일하게 나타났다. 다층의 다공질규소층 및 다공질규소 발광층의 두께를 각각 실호파장의 1/4배 및 2배가 되도록 하였을 때 특정파장의 필터로 쓰일 수 있는 브래그 반사경(Brag reflector)의 특성이 나타났다. 또한 PSM의 발광 스펙트럼은 그 반치폭이 현저히 감소하고 발광의 세기가 크게 증가되는 경향을 보였다. By periodically varying the current density and etching time during anodic oxidation of crystalline silicon wafers in 15% HF-ethanol solution, we obtained porous silicon multilayers which have periodically varying refractive index. We fabricated the porous silicon microcavity (PSM) which consist of porous silicon multilayers(Ⅰ), active layer of porous silicon, and porous silicon multilayers(Ⅱ) and investigated its physical properties. The AFM (Atomic Force Microscope) measurement from the cross section of multilayers (Ⅰ and Ⅱ) shows uniformity of high refractive index and low index layers as well as the active layer. We observed the characteristics of Bragg reflector when the thickness of layers was 1/4 and the thickness of active layer was twice of the effective wavelength, which can be used as a filter for specific wavelength. We found the emission characteristic from the PSM, which FWHM (full width half maximum) was considerably decreased and emission intensity was increased.

      • 백서의 정상 및 재생간의 Cytosol이 간에 일으키는 구조적 변화

        김통일,손기섭 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.1

        The purpose of this study is to make it clear the cause and the mechanism of liver regeneration. This study was underwent to evaluate the histopathological changes of normal and regenerating liver of rats, were treated with normal and regenerating liver cytosol which were made in three different ways. Three kind of liver cytosols were prepared from 50 normal healthy adult rats, normal liver cytosol were extracted from 10 rats, one day regenerating liver cytosol were extracted from 20 rats and 8 days regenerating liver cytosol were extracted from 20 rats after standard two-third partial hepatectomy. Experimental animals, 109 rats, were divided 12 groups, those were subdivided 3 groups in I, II, III and each group has 4 subgroups. A. B. C. D. respectively. Group I were rats with normal helathy liver and their specimen were taken out from the liver 24 hours later after treated with each test substances respectively. Group II were rats with partially hepatectomized and their specimen took cut from the regenerating liver 12 hours later after treated with each test substances respectively. Group III were same as II group in treatment, but the time taking out specimen is 24 hours later after treated with each test substances respectively. Subgroup A were treated with buffer solution Subgroup B were treated with normal liver cytosol Subgroup C were treated with one day regenerating liver cytosol Subgroup D were treated with 8 days regenerating liver cytosol The results of this experimental study were summarized as follows: 1. The liver regeneration, mitotic figures were prominent in group II-C and group II-D. 2. It seems that liver regeneration occured remarkably in the standard two-thirds partial hepatectomized liver of rats. 3. The liver cytosol extracted from the liver one day after resection has the most prominent ability of stimulation for regeneration of the liver. 4. It seems that the stimulaing factor of regeneration exists in the liver parenchyma itself. 5. The incidence of liver regeneration in the rats seems to begin immediately after resection of the liver and a peak is reached some 12 hours later.

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