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DISCOVERY OF A STRONG LENSING GALAXY EMBEDDED IN A CLUSTER AT z = 1.62
WONG, KENNETH C.,TRAN, KIM-VY H.,SUYU, SHERRY H.,MOMCHEVA, IVELINA G.,BRAMMER, GABRIEL B.,BRODWIN, MARK,GONZALEZ, ANTHONY H.,HALKOLA, ALEKSI,KACPRZAK, GLENN G.,KOEKEMOER, ANTON M.,PAPOVICH, CASEY J.,R The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2
We identify a strong lensing galaxy in the cluster IRC 0218 that is spectroscopically confirmed to be at z = 1.62, making it the highest-redshift strong lens galaxy known. The lens is one of the two brightest cluster galaxies and lenses a background source galaxy into an arc and a counterimage. With Hubble Space Telescope (HST) grism and Keck/LRIS spectroscopy, we measure the source redshift to be $z_S=2.26$. Using HST imaging, we model the lens mass distribution with an elliptical power-law profile and account for the effects of the cluster halo and nearby galaxies. The Einstein radius is $^{\theta}E=0.38^{+0.02{\prime}{\prime}}_{-0.01}$ ($3.2^{+0.2}_{-0.1}kpc$) and the total enclosed mass is $M_{tot}(<^{\theta}_E)=1.8^{+0.2}_{-0.1}{\times}10^{11}M_{\odot}$. We estimate that the cluster environment contributes ~ 10% of this total mass. Assuming a Chabrier IMF, the dark matter fraction within $^{\theta}E$ is $f^{Chab}_{DM}=0.3^{+0.1}_{-0.3}$, while a Salpeter IMF is marginally inconsistent with the enclosed mass ($f^{Salp}_{DM}=-0.3^{+0.2}_{-0.5}$).
In vivo wide-area cellular imaging by side-view endomicroscopy
Kim, Pilhan,Chung, Euiheon,Yamashita, Hiroshi,Hung, Kenneth E,Mizoguchi, Atsushi,Kucherlapati, Raju,Fukumura, Dai,Jain, Rakesh K,Yun, Seok H Nature Publishing Group 2010 NATURE METHODS Vol.7 No.4
In vivo imaging of small animals offers several possibilities for studying normal and disease biology, but visualizing organs with single-cell resolution is challenging. We describe rotational side-view confocal endomicroscopy, which enables cellular imaging of gastrointestinal and respiratory tracts in mice and may be extensible to imaging organ parenchyma such as cerebral cortex. We monitored cell infiltration, vascular changes and tumor progression during inflammation and tumorigenesis in colon over several months.
Sensing Nitrate and Potassium Ions in Soil Extracts Using Ion-Selective Electrodes
Kim, H.J.,Sudduth Kenneth A.,Hummel John W. Korean Society for Agricultural Machinery 2006 바이오시스템공학 Vol.31 No.6
Automated sensing of soil macronutrients would allow more efficient mapping of soil nutrient spatial variability for variable-rate nutrient management. The capabilities of ion-selective electrodes for sensing macronutrients in soil extracts can be affected by the presence of other ions in the soil itself as well as by high concentrations of ions in soil extractants. Adoption of automated, on-the-go sensing of soil nutrients would be enhanced if a single extracting solution could be used for the concurrent extraction of multiple soil macronutrients. This paper reports on the ability of the Kelowna extractant to extract macronutrients (N, P, and K) from US Corn Belt soils and whether previously developed PVC-based nitrate and potassium ion-selective electrodes could determine the nitrate and potassium concentrations in soil extracts obtained using the Kelowna extractant. The extraction efficiencies of nitrate-N and phosphorus obtained with the Kelowna solution for seven US Corn Belt soils were comparable to those obtained with IM KCI and Mehlich III solutions when measured with automated ion and ICP analyzers, respectively. However, the potassium levels extracted with the Kelowna extractant were, on average, 42% less than those obtained with the Mehlich III solution. Nevertheless, it was expected that Kelowna could extract proportional amounts of potassium ion due to a strong linear relationship ($r^2$ = 0.96). Use of the PVC-based nitrate and potassium ion-selective electrodes proved to be feasible in measuring nitrate-N and potassium ions in Kelowna - soil extracts with almost 1 : 1 relationships and high coefficients of determination ($r^2$ > 0.9) between the levels of nitrate-N and potassium obtained with the ion-selective electrodes and standard analytical instruments.
Building a successful fertility preservation program at a major cancer center
Jayeon Kim,Kenneth H Kim,Jennifer E Mersereau 대한부인종양학회 2014 Journal of Gynecologic Oncology Vol.25 No.2
Over 150,000 reproductive age individuals face fertility-threatening cancer treatments each year. Improved detection and treatment of cancer in reproductive-age patients have greatly increased the long-term survival and made it possible for these individuals to consider their long-term quality-of-life after cancer including having biologic offspring. Various methods of fertility preservation (FP) are now available for both males and females. In order to maximize FP options available to patients facing imminent gonadotoxic therapies, it is crucial that women have quick access to FP care and that providers expedite FP strategies. The overarching goal of a clinical FP program is to help patients and their physicians consider the impact of treatment on future fertility and facilitate FP efforts in what is often a limited time period before cancer treatment begins.
Rhee, Je-Keun,Kim, Kwangsoo,Chae, Heejoon,Evans, Jared,Yan, Pearlly,Zhang, Byoung-Tak,Gray, Joe,Spellman, Paul,Huang, Tim H.-M.,Nephew, Kenneth P.,Kim, Sun Oxford University Press 2013 Nucleic acids research Vol.41 No.18
<P>Aberrant DNA methylation of CpG islands, CpG island shores and first exons is known to play a key role in the altered gene expression patterns in all human cancers. To date, a systematic study on the effect of DNA methylation on gene expression using high resolution data has not been reported. In this study, we conducted an integrated analysis of MethylCap-sequencing data and Affymetrix gene expression microarray data for 30 breast cancer cell lines representing different breast tumor phenotypes. As well-developed methods for the integrated analysis do not currently exist, we created a series of four different analysis methods. On the computational side, our goal is to develop methylome data analysis protocols for the integrated analysis of DNA methylation and gene expression data on the genome scale. On the cancer biology side, we present comprehensive genome-wide methylome analysis results for differentially methylated regions and their potential effect on gene expression in 30 breast cancer cell lines representing three molecular phenotypes, luminal, basal A and basal B. Our integrated analysis demonstrates that methylation status of different genomic regions may play a key role in establishing transcriptional patterns in molecular subtypes of human breast cancer.</P>
Product market competition and corporate investment : Evidence from China
Fuxiu Jiang,Bing Zhu,Kenneth A. Kim,Suk H. Kim 한국재무학회 2015 한국재무학회 학술대회 Vol.2015 No.05
In contrast to recent studies using U.S. data, we find a positive relation between product market competition and corporate investment using a sample of Chinese manufacturing firms during 1999-2010. A quasi-natural experiment and change regressions yield consistent evidence. We contend that China’s high growth rate, as it transitions from a developing economy to a developed economy, is what drives the positive relation between competition and investment. We directly test and provide support for this growth-oriented explanation. We also find that high investment under high competition is a value-enhancing proposition for firms. Finally, we also test to see if there are some firm-types that are more likely to invest under high competition in a growing economy, and we find that firms with high predation risk, firms that are industry leaders, and firms with good governance are the ones that invest more.