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- 저자 : Karasu, Gaye (검색결과 5 건)
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Seda Karasu Yalcin 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.3
In order to enhance citric acid production by Yarrowia lipolytica 57, mutation and selection treatments were performed by using UV-irradiation and/or ethyl methane sulfonate (EMS) as a chemical mutagen. Totally 18 mutant strains were demonstrated by testing of 1,234colonies and then used in citric acid production studies. Chemical mutagenesis was found as more effective in enhancing citric acid production than UV-induced mutagenesis. Maximum citric acid concentration (50.1 g/L) and yield obtained by the chemical mutant Y. lipolytica K-168 exceeded that of the initial strain by 57%. Growth and citric acid production of this strain was further examined in natural fermentation media containing carrot juice or celery byproducts. Maximum citric acid concentration reached to 62.6 g/L in diluted carrot juice medium supplemented with glucose. It was determined that enriched carrot juice may serve as a good nutrient source and could be used for citric acid production by K-168strain.
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Characterization of diopside-based glass-ceramic porcelain tile glazes containing borax solid wastes
G. Kaya,B. Karasu,A. Cakir 한양대학교 세라믹연구소 2011 Journal of Ceramic Processing Research Vol.12 No.2
In recent years glass-ceramic systems became industrially important for their high softening point, good coating capability for relevant substrates and high chemical and abrasion resistance. The ZrO2-CaO-MgO-SiO2 (ZrCMS) glass-ceramic system exhibits a high resistance to abrasion and surface scratches thanks to the diopside crystals formed during firing. In this current study, certain amounts of wastes of the Eti Maden Krka Boron Company of Turkey possessing the world biggest borax deposit were evaluated in the production of ZrCMS system frits as being suitable for porcelain tile glazes. Newly-produced frit based glass-ceramic glazes were applied on porcelain tile bodies then, fast fired under both laboratory and industrial working conditions. The final products were characterized in terms of microstructural changes and phase formation, hardness, colour parameters and glossiness of glazed surfaces.
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Investigation of crossflow features of a slender delta wing
Mehmet O. Tasci,Ilyas Karasu,Besir Sahin,Huseyin Akilli 한국풍공학회 2020 Wind and Structures, An International Journal (WAS Vol.31 No.3
In the present work, the main features of primary vortices and the vorticity concentrations downstream of vortex bursting in crossflow plane of a delta wing with a sweep angle of Λ=70° were investigated under the variation of the sideslip angles, β. For the pre-review of flow structures, dye visualization was conducted. In connection with a qualitative observation, a quantitative flow analysis was performed by employing Particle Image Velocimetry (PIV). The sideslip angles, β were varied with four different angles, such as 0°, 4°, 12°, and 20° while angles of attack, α were altered between 25° and 35°. This study mainly focused on the instantaneous flow features sequentially located at different crossflow planes such as x/C=0.6, 0.8 and 1.0. As a summary, time-averaged and instantaneous non-uniformity of turbulent flow structures are altered considerably resulting in non-homogeneous delta wing surface loading as a function of the sideslip angle. The vortex bursting location on the windward side of the delta wing advances towards the leading-edge point of the delta wing. The trajectory of the primary vortex on the leeward side slides towards sideways along the span of the delta wing. Besides, the uniformity of the lift coefficient, CL over the delta wing plane was severely affected due to unbalanced distribution of buffet loading over the same plane caused by the variation of the sideslip angle, β. Consequently, dissimilarities of the leading-edge vortices result in deterioration of the mean value of the lift coefficient, CL.
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( Merve Sena Baytar ),( Canan Yılmaz ),( Derya Karasu ),( Çağdaş Baytar ) 대한통증학회 2021 The Korean Journal of Pain Vol.34 No.2
Background: Various truncal block techniques with ultrasonography (USG) are becoming widespread to reduce postoperative pain and opioid requirements in video-assisted thoracoscopic surgery (VATS). The primary aim of our study was to determine whether the USG-guided serratus anterior plane block (SAPB) is as effective as the thoracic paravertebral block (TPVB) in VATS. Our secondary aim was to evaluate patient and surgeon satisfaction, block application time, first analgesic time, and length of hospital stay. Methods: Patients in Group SAPB received 0.4 mL/kg bupivacaine with a USG-guided SAPB, and patients in Group TPVB received 0.4 mL/kg bupivacaine with a USG-guided TPVB. We recorded the pain scores, the timing of the first analgesic requirement, the amount of tramadol consumption, and postoperative complications for 24 hours. We also recorded the block application time and length of hospital stay. Results: A total of 62 patients, with 31 in each group (Group SAPB and Group TPVB) completed the study. Between the two groups, there were no significant differences in rest and dynamic pain visual analog scale scores at 0, 1, 6, 12, and 24 hours after surgery. The total consumption of tramadol was significantly lower in the TPVB group (P = 0.026). The block application time was significantly shorter in Group SAPB (P < 0.001). Conclusions: An SAPB that is applied safely and rapidly as a part of multimodal analgesia in patients who undergo VATS is not inferior to the TPVB and can be an alternative to it.
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Goksu, Sema Sezgin,Bozcuk, Hakan,Uysal, Mukremin,Ulukal, Ece,Ay, Seren,Karasu, Gaye,Soydas, Turker,Coskun, Hasan Senol,Ozdogan, Mustafa,Savas, Burhan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.21
Background: Pain is one of the most terrifying symptoms for cancer patients. Although most patients with cancer pain need opioids, complete relief of pain is hard to achieve. This study investigated the factors influencing persistent pain-free survival (PPFS) and opioid efficiency. Materials and Methods: A prospective study was conducted on 100 patients with cancer pain, hospitalized at the medical oncology clinic of Akdeniz University. Patient records were collected including patient demographics, the disease, treatment characteristics, and details of opioid usage. Pain intensity was measured using a patient self-reported visual analogue scale (VAS). The area under the curve (AUC) reflecting the pain load was calculated from daily VAS tables. PPFS, the primary measure of opioid efficacy, was described as the duration for which a patient reported a greater than or equal to two-point decline in their VAS for pain. Predictors of opioid efficacy were analysed using a multivariate analysis. Results: In the multivariate analysis, PPFS was associated with the AUC for pain (Exp (B)=0.39 (0.23-0.67), P=0.001), the cumulative opioid dosage used during hospitalisation (Exp (B)=1.00(0.99-1.00), P=0.003) and changes in the opioid dosage (Exp (B)=1.01 (1.00-1.01), P=0.016). The change in VAS score over the standard dosage of opioids was strongly associated with current cancer treatment (chemotherapy vs. others) (${\beta}=-0.31$, T=-2.81, P=0.007) and the VAS for pain at the time of hospitalisation (${\beta}=-0.34$, T=-3.07, P= 0.003). Conclusions: The pain load, opioid dosage, concurrent usage of chemotherapy and initial pain intensity correlate with the benefit received from opioids in cancer patients.
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