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- 저자 : Kankana Banerjee (검색결과 1 건)
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Chiranjib Chakraborty,Ashish Ranjan Sharma,Sharma Garima,Manojit Bhattacharya,Bidhan C. Patra,Bimal Kumar Sarkar,Saptarshi Banerjee,Kankana Banerjee,Sang‑Soo Lee 한국유전학회 2021 Genes & Genomics Vol.43 No.7
Background Currently, Tigers (the top predator of an ecosystem) are on the list of endangered species. Thus the need is to understand the tiger’s population genomics to design their conservation strategies. Objective We analyzed the molecular evolution of tiger diversity using NADH dehydrogenase subunit 4 (ND4), a signifcant electron transport chain component. Methods We have analyzed nucleotide composition and distribution pattern of ND genes, molecular evolution, evolutionary conservation pattern and conserved blocks of NADH, phylogenomics of ND4, and estimating species divergence, etc., using diferent bioinformatics tools and software, and MATLAB programming and computing environment. Results The nucleotide composition and distribution pattern of ND genes in the tiger genome demonstrated an increase in the number of adenine (A) and a lower trend of A+T content in some place of the distribution analysis. However, the observed distributions were not signifcant (P > 0.05). Evolutionary conservation analysis showed three highly align blocks (186 to 198, 406 to 416, and 527 to 545). On mapping the molecular evolution of ND4 among model species (n = 30), we observed its presence in a broader range of species. ND4 based molecular evolution of tiger diversity and time divergence for a tiger (20 diferent other species) shows that genus Panthera originated more or less at a similar time. Conclusions The nucleotide composition and nucleotide distribution pattern of tiger ND genes showed the evolutionary pattern and origin of tiger and Panthera lineage concerning the molecular clock, which will help to understand their adaptive evolution.
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