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김민근,주혜원,강경필,최병돈,박민석,변영섭,고충원,이건주,김병옥 인제대학교 2006 仁濟醫學 Vol.27 No.-
Acute myocardial infarction(AMI) due to coronary embolism can occur in patients with normal coronary artery. Coronary embolism is believed to be a cause of acute myocardial infarction when emergent coronary angiography shows perfectly normal coronary trees, except for the finding of coronary artery occlusion. In this report, we describe four patients with AMI due to coronary embolism who were successfully treated using a thrombus aspiration device and anticoagulation, and those patients had intracardial thrombus arising from the left atrium due to chronic atrial fibrillation and valvular heart disease. Patients with chronic or paroxysmal atrial fibrillation can present with AMI due to coronary embolism, and thrombus aspiration with percutaneous aspiration device is a feasible treatment option for these patients along with anticoagulation the rapy.
김충수,신석철,강민희 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2
To evaluate the effect of stress on immunological functions, lymphocyte subpopulation measure by flow cytometry technique, lymphocyte stimulation test using Con A and PHA, and the NK cell activity measure were performed on 12 medical students during test and vacation periods. The results were as follows : 1. The scores of GARS, SAS and SDS were significantly increased during test compared to the vacation periods (P<0.001). 2. There were no differences in the absolute numbers and percentages of the total lymphocyte, B-cell, T-cell, T-cell subset and NK cell between the test and vacation periods. 3. NK cell activities were significantly decreased during the test periods compared to the vacation periods (P<0.001 or P<0.01). 4. Lymphocyte proliferation response by PHA was significantly decreased during test periods compared to the vacation periods (P<0.05). 5. There were no significant correlations between the amount of increase in stress and the amount of decrease in NK cell activity or lymphocyte proliferation response.
육철,강충민 永同大學校 2000 硏究論叢 Vol.6 No.1
Honey comb에서 분리한 Trichosporonides sp. 의 최적 생산성 조건을 구하기 위하여 에리스리톨 생산에 영향을 미치는 인자들을 결정하고 각각의 인자의 수준을 설정하여 직교배열법을 이용한 최적조건을 구하였다. Trichosporonides sp.는 포도당 농도 40%까지 정상적인 생육을 보였으나 포도당 농도가 20% 일 때 가장 좋은 에리스리톨 생산성을 보였으며 산소전달속도에 따라 생산성이 현저하게 변하였다. 직교배열표 L27(313)을 이용하여 구한 배양 최적조건은 yeast extract 0.45, KNO3 0.3%, 포도당 20%, 배양온도 34℃로 나타났으며, 이 조건에서 Trichosporonides sp. 는 에리스리톨을 0.74 g/L/h의 속도로 생산하였다. 그리고 이 값은 실험계획법에 의한 최적조건에서의 예측치 (0.7231 g/L/h)와 잘 일치하였으며 3회 반복 실험한 결과 95% 신뢰구간에서도 유의한 것으로 판명되었다. Tables of orthogonal arrays were used to find out optimum condition for production of erythritol by Trichosporonides sp. isolated from honey comb. Trichosporonides sp. grew normally even at the concentration of 40% of glucose and showed the best productivity of erythritol at the concentration of 20%. From the tables of orthogonal arrays, L27(313), 27 conditions were selected and tested. The optimum conditions for temperature and concentrations of yeast extract, KNO3 and glucose were 34℃ , 0.4%, 0.3% and 20%, respectively. The productivity of erythritol at the condition was 0.74 g/L/h which was very close to estimated value(0.7231 g/L/h). It was confirmed with 95% confidence by 3 repeated experiments.
장재훈,김강민,김태우,정현광,조윤성,서수홍,이충원 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2
Elastofibroma is a rare, benign, soft-tissue tumor that usually located at the inferior pole of the scapula. It is important to differentiate this tumor from other soft-tissue tumors such as sarcoma, fibromatosis, metastatic tumor, and lipoma. A 57-year-old female who complained of chronic both shoulder pain was admitted to our hospital with bilateral, soft tissue masses located in the subscapular region. Ultrasonography, CT and MRI images showed bilateral inhomogeneous tumors that measured 7×3×6 cm. This was compatible with elastofibroma by fine-needle aspiration biopsy. Shoulder pain was gone with decreasing size of masses after conservative treatment and avoiding workload to the shoulder. We present this case with a review of literatures.
미세입자(PM_(2.5))의 배출원 구성물질 성분비 개발에 관한 연구
이학성,강충민,강병욱,이상권 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.3
The purpose of this study was to develop the PM_(2.5) source profiles, which are mass abundances (fraction of total mass) of a chemical species in PM_(2.5) source emissions. The source categories studied were soil, road dust, gasoline and diesel vehicles, industrial source, municipal incinerator, coal-fired power plant, biomass burning, and marine. The chemicals analyzed were ions, elements, and carbons. From this study. soil source had the crustal components such as Si, AI, and Fe. In the case of road dust, Si, OC, Ca, Fe had large abundances. The abundant species were SO₄^(2-), Cl^(-), NH₄^(+), and EC in the gasoline vehicle and EC, OC, Cl^(-), and SO₄^(2-) in the diesel vehicle. The main components were SO₄^(2-), S, NH₄^(+), and EC in the industrial source using bunker C oil as fuel. ^(-), NH₄^(+), Fe, and OC in the municipal incinerator source, and Si, Al, SO₄^(2-), and OC in the coal-fired power plant source. In the case of biomass burning, OC, EC, and CI- were mainly emitted. The main components in marine were Cl^(-), Na^(+), and SO₄^(2-).
Yu Jin Cho,Jae Chul Lee,Bong Gu Kang1,2,Jaeyeol An,Hyeon Suk Song1,2,Onju Son,Do-Hyun Nam,Choong Ik Cha,Kyeung Min Joo 대한해부학회 2011 Anatomy & Cell Biology Vol.44 No.2
Nitric oxide (NO) modulates the activities of various channels and receptors to participate in the regulation of neuronal intracellular Ca2+ levels. Ca2+ binding protein (CaBP) expression may also be altered by NO. Accordingly, we examined expression changes in calbindin-D28k, calretinin, and parvalbumin in the cerebral cortex and hippocampal region of neuronal NO synthase knockout(−/−) (nNOS−/−) mice using immunohistochemistry. For the first time, we demonstrate that the expression of CaBPs is specifically altered in the cerebral cortex and hippocampal region of nNOS−/− mice and that their expression changed according to neuronal type. As changes in CaBP expression can influence temporal and spatial intracellular Ca2+ levels, it appears that NO may be involved in various functions, such as modulating neuronal Ca2+ homeostasis, regulating synaptic transmission, and neuroprotection, by influencing the expression of CaBPs. Therefore, these results suggest another mechanism by which NO participates in the regulation of neuronal Ca2+ homeostasis. However, the exact mechanisms of this regulation and its functional significance require further investigation.
Choong-Min Kang,Byung-Wook Kang,Young Sunwoo,Hak Sung Lee 한국대기환경학회 2008 한국대기환경학회지 Vol.24 No.E1
Source samples were collected to construct source profiles for 9 different source types, including soil, road dust, gasoline/diesel-powered vehicles, a municipal incinerator, industrial sources, agricultural/biomass burning, marine aerosol, and a coal-fired power plant. Seasonal profiles for ‘Chinese aerosol’, aerosols derived from the urban area of China, were reconstructed from seasonal PM2.5 compositions reported in Beijing, China. Ambient PM2.5 at a receptor site was also measured during each of the four seasons, from April 2001 to February 2002, in Seoul. The Chemical Mass Balance receptor model was applied to quantify source contributions during the study period using the estimated source profiles. Consequently, motor vehicle exhaust (33.0%), in particular 23.9% for diesel-powered vehicles, was the largest contributor affecting the PM2.5 levels in Seoul, followed by agricultural/biomass burning (21.5%) and 'Chinese aerosol' (13.1%), indicating contributions from long-range transport. The largest contributors by season were: for spring, 'Chinese aerosol' (31.7%); for summer, motor vehicle exhaust (66.9%); and for fall and winter, agricultural/biomass burning (31.1% and 40.1%, respectively). These results show different seasonal patterns and sources affecting the PM2.5 level in Seoul, than those previously reported for other cities in the world.
A Modified Immunoblot Method to Identify Substrates of Protein Kinases
Choong-Min Kang,Wan Jin Jahng,Robert N. Husson,이상희 한국미생물학회 2011 The journal of microbiology Vol.49 No.3
While protein kinases are key components in multiple cellular processes, efficient identification of cognate in vivo substrates remains challenging. Here we describe a powerful method to screen potential substrates of protein kinases by partial transfer of proteins from a 2D-PAGE gel to a Western blot membrane. This approach allowed precise pinpointing of candidate substrate spots in the 2D gel, and identifying physiological substrates of protein kinases in Mycobacterium tuberculosis.
대왕바리 암컷을 사용한 두 교잡(대왕바리♀×자바리♂, 대왕바리♀× 붉바리♂) 수정란의 난 발생과 부화력
강민주 ( Min Joo Kang ),노충환 ( Choong Hwan Noh ),김재훈 ( Jae Hun Kim ),박종연 ( Jong Yeon Park ),박대원 ( Dae Won Park ) 한국수산과학회(구 한국수산학회) 2020 한국수산과학회지 Vol.53 No.4
As part of an effort to establish of novel grouper hybrids for the aquaculture industry, we compared the embryonic development of fertilized eggs of giant grouper Epinephelus lanceolatus ♀×kelp grouper E. bruneus ♂ (GGKG) and giant grouper ♀×red-spotted grouper E. akaara ♂ (GGRG) with a maternal purebred (giant grouper ♀×♂, GG) at 27- 29℃. The hatching rates were lower in GGKG (2.59%) and GGRG (0.36%) than in GG (12.29%). The hatching times were considerably longer in the two hybrids than in GG (22 h), which were similar between GGKG (28 h 30 min) and GGRG (28 h). The total lengths of yolk-absorbed larvae of GGKG (2.546±0.132 mm) and GGRG (2.602±0.093 mm) were similar to that of GG (2.565±0.149 mm). The deformity rates of hatched larvae (64.29-75.00%) did not differ between the two hybrids and GG. Although the hatching and deformity rates of GGKG and GGRG were inferior to those of GG, the possibility of mass production of the two hybrids larvae was demonstrated in this study.