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Lipid-Hydrogel-Nanostructure Hybrid and Its Anti-Biofilm Properties
Hyun-Ha Park(박현하),Kahyun Sun(선가현),Hoon Yi(이훈),Hangil Ko(고한길),Minho Seong(성민호),Insol Hwang(황인솔),SangHyun Lee(이상현),Minsu Kang(강민수),Hyunwook Ko(고현욱),Hoon-Eui Jeong(정훈의) 대한기계학회 2018 대한기계학회 춘추학술대회 Vol.2018 No.12
Despite extensive efforts toward developing anti-biofilm materials, efficient prevention of biofilm formation remains challenging. Diverse polymeric materials with bactericidal or antifouling properties have strong potential as efficient antibiofilm materials. However, approaches based on a single strategy using either bactericidal polymers, antifouling coatings, or nano-patterning of polymers have shown limited performance in the prevention of biofilm formation. This study presents a lipid-hydrogel-nanotopography hybrid that has highly efficient biofilm-resistant properties. The hybrid material consists of nanostructured antifouling, biocompatible polyethylene glycol (PEG)-based polymer covered with a membrane-mimicking, antifouling, biocompatible zwitterionic polymer of 2-methacryloryloxyethyl phosphorylcholine (MPC). Surface chemistry of the polymeric hybrid is analyzed with attenuated total reflectance-fourier transform infrared (ATR-FTIR) spectroscopy and x-ray photoelectron spectroscopy (XPS). Based on the unique heterogeneous chemical compositions, the lipid-hydrogel-nanostructure hybrid exhibits superior dual functionalities of antifouling and bactericidal activities against gram-negative and -positive bacteria, compared with those of surfaces composed of single type of polymer.
Large-area, Multipixel Photonic Skin Based On a Shape-memory and Responsive Cellulose Derivative
Sang-Hyeon Lee(이상현),Kahyun Sun(선가현),Minho Seong(성민호),Insol Hwang(황인솔),Minsu Kang(강민수),Jaeil Kim(김재일),Geonjun Choi(최건준),Hyejin Jang(장혜진),Seongjin Park(박성진),Hoon Eui Jeong(정훈의) 대한기계학회 2020 대한기계학회 춘추학술대회 Vol.2020 No.12