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Jun Rho Yoon,Tae Kwan Kim,Je Chun Yu,Yee Suk Kim,In Soo Han,Yong Ju Oh Korean Society of Critical Care Medicine 2007 Acute and Critical Care Vol.22 No.1
A 73-year-old man was scheduled for the surgical reduction of fractured femur which occurred ar 3 months ago by the accident. The mental status of the patient was stuporous (Glasgow coma scale: 5) due to the complication of the head trauma. We performed nerve blocks (femoral, sciatic, lateral femoral cutaneous, and illiohypogastric nerve blocks) for the surgical reduction of left femur with 55 ml of 0.25% ropivacaine. The electroencephalography was monitored continuously during the 4 hour operation as well as monitoring the hemodynamic and respiratory parameters. The operation was performed successfully and the patient recovered uneventfully.
Severe Postoperative Delirium Lasting for Three Weeks: A Case Report
Jun Rho Yoon,Tae Kwan Kim,Su Jung Yoon,Yee Suk Kim,Si Hyun Kim,Man Gyu Kim,Jeong Ju Seo Korean Society of Critical Care Medicine 2004 Acute and Critical Care Vol.19 No.1
Postoperative delirium in the intensive care unit is a serious problem that has recently attracted much attention. We present a 73-year-old female patient who was admitted by multiple fractures induced by an accident. We started general anesthesia for the operation of open reduction and internal fixation. After the discontinuation of general anesthesia, the patient was transported to the intensive care unit. The symptoms of delirium were developed and controlled with medications including haloperidols, benzodiazepines, and vitamins. The patient was recovered three weeks after the management and received two other operations, but delirium did not be developed again. She was discharged from the hospital without complications.
증례보고 : 뇌동맥류 색전술 중 헤파린첨가 생리식염수의 동맥 내 과다 주입으로 발생한 폐부종
윤준로 ( Jun Rho Yoon ),김태관 ( Tae Kwan Kim ),이민규 ( Min Gyu Lee ),오용주 ( Yong Ju Oh ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.53 No.6
Here we report, along with a review of the literature, our experience with a patient suffering from a cerebral aneurysm and developed volume overloading pulmonary edema during endovascular coiling. A 51-year-old female patient who had an aneurysm in the basilar artery tip and subarachnoid hemorrhage was scheduled for endovascular embolization under general anesthesia. She developed pulmonary edema during the procedure. Coiling failed so neurosurgeon performed aneurysmal clipping under general anesthesia. The massive intraarterial infusion and flushing with heparinized saline may have triggered the pulmonary edema. We monitored diuresis and hemodynamics following surgery, as a high degree of vigilance, including monitoring of arterial blood gas and electrolyte evaluation, of patients undergoing prolonged endovascular embolization and receiving many intra-arterial fluids may help recovery. (Korean J Anesthesiol 2007; 53: 810~4)
윤준로(Jun Rho Yoon),한석호(Seok Ho Han),정은용(Eu 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.2
N/A Background: Continuous epidural block is widely used for surgical operation and postoperative pain management. The potential infection due to the epidural catheter is a definite harzard of continous epi- dural block We investigated the effectiveness of bacterial filter in pmvention of infection due to the epidural catheter. Methods: Patients scheduled for transabdominal hysterectomy were assigned to two groups by simple randomization (50 patients per group). All catheters were placed in the 2nd and 3rd lumbar epidural space, using careful sterile technique. Group 1 received injections by the epidural catheter with a bacterial filter and group 2 received injections by the epidural catheter without a bacterial filter. The infection rate in the tips of epidural catheter left for 3 days were compared between the two groups. Results: There was no significant difference in the infection rate between two groups. Conclusions: A bacterial filter of the epidural catheter for surgical anesthesia and postoperative analge- sia dose not prevent all kinds of infection in continuous epidural block.
윤준로 ( Jun Rho Yoon ),정은용 ( Eun Yong Jung ),김미정 ( Mi Jung Kim ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.56 No.1
Background: Advances in the field of interventional and diagnostic radiology have resulted in anesthesiologists becoming involved in angiographic suites. In the present study, we evaluated the characteristics of patients and the anesthetic management in an angiographic suite, to determine what factors influenced the patient outcome. Methods: Data pertaining to patients that were anesthetized at an angiographic suite in a university hospital between 1 January 2007 and 31 December 2007 were evaluated retrospectively. Specifically, we evaluated the patient characteristics and the types of anesthesia administered, to determine which factors were related to patient outcome. Results: Sixty-four percent of the patients enrolled in this study were women. Cases involving coiling for unruptured and ruptured aneurysm, embolization for intracranial arteriovenous malformation and fistula, pediatric diagnostic angiography, embolization for extracranial arteriovenous malformation, and implantable cardioverter-defibrillator (ICD) implantation all required the involvement of anesthesiologists. Major postoperatve complications included pneumonia, atelectasis, and hydrocephalus. In addition, GCS, net fluid balance, and anesthesia time had influence on patient outcome. Conclusions: We evaluated the characteristics of patient groups, procedures, and postoperative complications in an angiographic suite. The results of our analysis revealed that a through understanding of nervous and vascular pathology, as well as knowledge of current interventional radiology, neuroanesthesia and vascular anesthesia techniques is essential for development of safe and effective care. (Korean J Anesthesiol 2009;56:36~46)
Anti-inflammatory activity of AP-SF, a ginsenoside-enriched fraction, from Korean ginseng
Kwang-Soo Baek,Yong Deog Hong,Yong Kim,Nak Yoon Sung,Sungjae Yang,Kyoung Min Lee,Joo Yong Park,Jun Seong Park,Ho Sik Rho,Song Seok Shin,조재열 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.2
Background: Korean ginseng is an ethnopharmacologically valuable herbal plant with various biologicalproperties including anticancer, antiatherosclerosis, antidiabetic, and anti-inflammatory activities. Sincethere is currently no drug or therapeutic remedy derived from Korean ginseng, we developed a ginsenoside-enriched fraction (AP-SF) for prevention of various inflammatory symptoms. Methods: The anti-inflammatory efficacy of AP-SF was tested under in vitro inflammatory conditionsincluding nitric oxide (NO) production and inflammatory gene expression. The molecular events of inflammatoryresponses were explored by immunoblot analysis. Results: AP-SF led to a significant suppression of NO production compared with a conventional Koreanginseng saponin fraction, induced by both lipopolysaccharide and zymosan A. Interestingly, AP-SFstrongly downregulated the mRNA levels of genes for inducible NO synthase, tumor necrosis factor-a,and cyclooxygenase) without affecting cell viability. In agreement with these observations, AP-SF blockedthe nuclear translocation of c-Jun at 2 h and also reduced phosphorylation of p38, c-Jun N-terminalkinase, and TAK-1, all of which are important for c-Jun translocation. Conclusion: Our results suggest that AP-SF inhibits activation of c-Jun-dependent inflammatory events. Thus, AP-SF may be useful as a novel anti-inflammatory remedy.
Anti-inflammatory activity of AP-SF, a ginsenoside-enriched fraction, from Korean ginseng
Baek, Kwang-Soo,Hong, Yong Deog,Kim, Yong,Sung, Nak Yoon,Yang, Sungjae,Lee, Kyoung Min,Park, Joo Yong,Park, Jun Seong,Rho, Ho Sik,Shin, Song Seok,Cho, Jae Youl The Korean Society of Ginseng 2015 Journal of Ginseng Research Vol.39 No.2
Background: Korean ginseng is an ethnopharmacologically valuable herbal plant with various biological properties including anticancer, antiatherosclerosis, antidiabetic, and anti-inflammatory activities. Since there is currently no drug or therapeutic remedy derived from Korean ginseng, we developed a ginsenoside-enriched fraction (AP-SF) for prevention of various inflammatory symptoms. Methods: The anti-inflammatory efficacy of AP-SF was tested under in vitro inflammatory conditions including nitric oxide (NO) production and inflammatory gene expression. The molecular events of inflammatory responses were explored by immunoblot analysis. Results: AP-SF led to a significant suppression of NO production compared with a conventional Korean ginseng saponin fraction, induced by both lipopolysaccharide and zymosan A. Interestingly, AP-SF strongly downregulated the mRNA levels of genes for inducible NO synthase, tumor necrosis factor-${\alpha}$, and cyclooxygenase) without affecting cell viability. In agreement with these observations, AP-SF blocked the nuclear translocation of c-Jun at 2 h and also reduced phosphorylation of p38, c-Jun N-terminal kinase, and TAK-1, all of which are important for c-Jun translocation. Conclusion: Our results suggest that AP-SF inhibits activation of c-Jun-dependent inflammatory events. Thus, AP-SF may be useful as a novel anti-inflammatory remedy.
Rho, Won-Yeop,Choi, Jung-Woo,Lee, Hea-Yeon,Kyeong, San,Lee, Sang Hun,Jung, Heung Su,Jung, Seunho,Sung, Yung-Eun,Lee, Yoon-Sik,Jun, Bong-Hyun The Royal Society of Chemistry 2014 NEW JOURNAL OF CHEMISTRY Vol.38 No.3
<P>A dye-sensitized solar cell (DSSC) was fabricated using silica-coated quantum dot-embedded silica nanoparticles (SiO<SUB>2</SUB>/QD/SiO<SUB>2</SUB> NPs) as a light-harvesting layer. Compared to an unmodified DSSC, the power conversion efficiency of a DSSC with SiO<SUB>2</SUB>/QD/SiO<SUB>2</SUB> NPs (SiO<SUB>2</SUB>/QD/SiO<SUB>2</SUB> DSSC) increased from 3.92% to 4.82%, an enhancement of approximately 23.0%.</P> <P>Graphic Abstract</P><P>A dye-sensitized solar cell (DSSC) was fabricated using silica-coated quantum dot-embedded silica nanoparticles as a light-harvesting layer. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3nj01345f'> </P>
Rho, Won-Yeop,Kim, Ho-Sub,Chung, Woo-Jae,Suh, Jung Sang,Jun, Bong-Hyun,Hahn, Yoon-Bong Elsevier 2018 APPLIED SURFACE SCIENCE - Vol.429 No.-
<P><B>Abstract</B></P> <P>We have investigated the effect of TiO<SUB>2</SUB> nanoparticles/TiO<SUB>2</SUB> nanotubes-Ag nanoparticles (TiO<SUB>2</SUB>NPs/NTs-Ag@TiO<SUB>2</SUB> NPs) composites on the performance of dye-sensitized solar cells (DSSCs). The DSSC showed the power conversion efficiency (PCE) of 8.04% with TiO<SUB>2</SUB> NPs film only and 8.78% with TiO<SUB>2</SUB> NPs/NTs due to the improvement of electron transport through nanotubes. More interestingly, compared to the device with TiO<SUB>2</SUB> NPs film only, the TiO<SUB>2</SUB> NPs/NTs-Ag@TiO<SUB>2</SUB> NPs composites led to dramatic increases in <I>J<SUB>sc</SUB> </I> from 12.46 to 16.46mA/cm<SUP>2</SUP> (i.e., 32% increase) and PCE from 8.04 to 10.60% (i.e., 32% increase), attributed to a synergetic effect of fast electron conduction through TiO<SUB>2</SUB> NTs and plasmonic enhancement of Ag NPs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Composites composed of TiO<SUB>2</SUB> nanoparticles/nanotubes and Ag@TiO<SUB>2</SUB> nanoparticles for dye-sensitized solar cells (DSSCs). </LI> <LI> Dramatic increase in photocurrent density and power conversion efficiency with the composite-based DSSCs. </LI> <LI> A synergetic effect of fast electron conduction through TiO<SUB>2</SUB> NTs and plasmonic enhancement of Ag NPs. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>