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      • Polyphenolics in Grape Seeds―Biochemistry and Functionality

        John Shi,Jianmel Yu,Joseph E. Pohorly,Yukio Kakuda 한국식품영양과학회 2003 Journal of medicinal food Vol.6 No.4

        Grape seeds are waste products of the winery and grape juice industry. These seeds contain lipid, protein, car-bohydrates, and 5 8% polyphenols depending on the variety. Polyphenols in grape seeds are mainly flavonoids, including gal-lic acid, the monomeric flavan-3-ols catechin, epicatechin, gallocatechin, epigallocatechin, and epicatechin 3-O-gallate, andprocyanidin dimers, trimers, and more highly polymerized procyanidins. Grape seed extract is known as a powerful antioxi-dant that protects the body from premature aging, disease, and decay. Grape seeds contains mainly phenols such as proan-thocyanidins (oligomeric proanthocyanidins). Scientific studies have shown that the antioxidant power of proanthocyanidinsis 20 times greater than vitamin E and 50 times greater than vitamin C. Extensive research suggests that grape seed extractis beneficial in many areas of health because of its antioxidant effect to bond with collagen, promoting youthful skin, cellhealth, elasticity, and flexibility. Other studies have shown that proanthocyanidins help to protect the body from sun damage,to improve vision, to improve flexibility in joints, arteries, and body tissues such as the heart, and to improve blood circula-tion by strengthening capillaries, arteries, and veins. The most abundant phenolic compounds isolated from grape seed arecatechins, epicatechin, procyanidin, and some dimers and trimers.

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