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- 저자 : Joonhong Sohn (검색결과 5 건)
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Ocular Toxocariasis in an HIV-Positive Patient
Jeong Hee Kim,Joonhong Sohn,Duck Jin Hwang 대한검안학회 2017 Annals of optometry and contact lens Vol.16 No.3
Purpose: The aim of this study was to detail the first case of a patient with ocular toxocariasis, as an initial manifestation, who was eventually diagnosed with a positive human immunodeficiency virus (HIV) infection. Case summary: A 44-year-old man presented with a 1-month history of blurred vision and metamorphopsia in the right eye. He had no other relevant medical history. He denied having traveled out of the country or having any contact with animals or animal feces. He also denied consuming raw cow liver. At his initial visit, his best corrected visual acuity was 20/250 in the right eye, and 20/20 in the left eye. In the slit lamp examination, the conjunctiva of both eyes was clear and no inflammatory cells were observed. A dilated fundus examination and spectral domain optical coherence tomography revealed inflammatory exudates with fibrous tissue in the macula of the right eye. Toxocariasis antibody was serologically confirmed using enzyme-linked immunosorbent assay (ELISA), while HIV infection was confirmed by ELISA and western blotting. Conclusion: Because the ocular toxocariasis can be the first clinical manifestation in HIV-positive patients, the presence of ocular toxocariasis cannot exclude HIV infection and coinfection should be considered.
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Young Seong Yang,Joonhong Sohn,손지성,Ji Shin Lee 대한안과학회 2019 Korean Journal of Ophthalmology Vol.33 No.2
Purpose: To determine the origin of epiretinal proliferation (EP), a condition that is occasionally observed inlamellar hole and macular hole cases, and EP outcomes after vitrectomy. Methods: This is a retrospective observational case review of 17 eyes with EP that underwent vitrectomy, EPdissection, and internal limiting membrane peeling between January 2013 and December 2016. Surgical specimensof EP tissue were successfully obtained from 5 cases and they were analyzed after immunohistochemicalstaining. Postoperative outcomes, including best-corrected visual acuity (BCVA) and macular configurationin spectral domain-optical coherence tomography, were reviewed. Results: Mean BCVA improved from 0.54 ± 0.36 logarithms of the minimum angle of resolution preoperativelyto 0.32 ± 0.38 logarithms of the minimum angle of resolution postoperatively (p = 0.002). BCVA improvedin 13 eyes and remained unchanged in four eyes. No cases experienced vision decline after surgery. All 17patients’ lamellar hole or macular hole were successfully closed. Despite hole closure, ellipsoid zone defectswere not corrected in 11 of the 17 patients. In immunohistochemical analyses, anti-glial fibrillary acidic proteinand pan-keratin (AE1/AE3) were positive, but synaptophysin, anti-α-smooth muscle actin, and anti-CD68 werenegative. Conclusions: The epiretinal proliferative membrane seems to originate from Müller cells, not from the vitreous. Itis unclear whether retinal pigment epithelia also contribute to EP formation. Gentle handling and preservationof the epiretinal proliferative tissue is crucial for successful surgical outcomes.
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Effect of Anti-glaucoma Agents on Myopic Retinoschisis
Kyuhwan Jang,Junghwa Lee,Kyungmin Lee,Mi Jeung Kim,Joonhong Sohn 대한안과학회 2020 Korean Journal of Ophthalmology Vol.34 No.6
Purpose: To evaluate the effect of intraocular pressure (IOP)-lowering medications on myopic retinoschisis. Methods: The medical records of 33 patients (36 eyes) with myopic retinoschisis associated with pathologic myopia werereviewed retrospectively. The patients were divided into two groups: the study group comprising patients undergoing treatmentwith anti-glaucoma medications for suspected glaucoma; the control group comprising patients who did not use anyIOP lowering medications. The changes in retinoschisis in the two groups were compared using the Spectralis domain opticalcoherence tomography thickness map protocol. Results: The study group included 18 eyes (17 patients), and the control group included 18 eyes (16 patients). There were nosignificant differences between the 6-month and 12-month improvement or aggravation rates of the two groups (p = 0.513and 0.137, respectively). However, after 18 months, the aggravation rate of retinoschisis was significantly lower in the studygroup (p = 0.003). The improvement / aggravation rate was 58.33% / 16.67% in the study group and 0% / 57.14% in the controlgroup. Conclusions: The use of IOP-lowering medications for more than a year may be useful for the management of retinoschisisassociated with pathologic myopia.
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비증식당뇨망막병증에서 Calcium Dobesilate가 시력 및 황반두께에 미치는 영향
전성연(Sung Yeon Jun),박지인(Ji In Park),손준홍(Joonhong Sohn),황덕진(Daniel Duck-Jin Hwang) 대한검안학회 2021 Annals of optometry and contact lens Vol.20 No.2
Purpose: This study aimed to evaluate the effect of calcium dobesilate uptake on visual acuity (VA) and macular thickness by optical coherence tomography (OCT) of eyes with non-proliferative diabetic retinopathy (NPDR) in comparison with bilberry dried extract. Methods: Thirty-six eyes of 36 patients diagnosed with NPDR without macular edema and who were treated with calcium dobesilate for more than 6 months were enrolled in the calcium dobesilate (CAD) group. VA, diabetic retinopathy grade, central macular thickness (CMT), and total macular volume (TMV) at baseline and at the 3- and 6-month follow-up examinations were analyzed retrospectively. The matched patients treated with bilberry dried extract were selected and compared as the control group. Results: The CMT and TMV values were 282.14 ± 31.86, 277.96 ± 31.13, and 281.18 ± 30.41 μm and 8.79 ± 0.58, 8.68 ± 0.59, and 8.73 ± 0.60 ㎣ in the CAD group at baseline and at the 3- and 6-month follow-up, respectively. The TMV had decreased significantly at the 3-month follow-up (p = 0.027); however, the TMV at the 6-month follow-up and the VA and TMV at the 3- and 6-month follow-ups showed no differences from the baseline levels (all p > 0.05). In the control group, no significant changes in VA or in CMT were observed at 3 and 6 months after treatment compared to the baseline (all p > 0.05). Furthermore, no significant difference in CMT on OCT was observed between the two groups at all time points (all p > 0.05). Conclusions: In NPDR patients without macular edema, CAD uptake had no significant effect on VA or macular thickness until 6 months after treatment.
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