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심종성 ( Sim¸ Jongsung ),박철우 ( Park¸ Choelwoo ),박성재 ( Park¸ Sungjae ),강태성 ( Kang¸ Taesung ),박성은 ( Park¸ Seongeun ) 한국구조물진단유지관리공학회 2008 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.12 No.1
This study investigated fundamental properties of the recycled aggregate which was produced through recent hi-techniques of recycling. In addition, the mechanical properties of the concrete that used the recycled aggregate were compared th the concrete use the natural aggregate. The primary objective of this study was to characterize the concrete-rebar bonding properties of the recycled aggregate concrete. From the results of the mechanical property tests, as the recycled aggregate replacement ratio increased, the compressive strength and elastic modulus decreased. The recycled aggregate concrete showed about 18% decreased bond strength comparing to the concrete that had the same strength and used only the natural aggregate. The current bond strength prediction equation suggested by the design specification does not consider this decreased bong strength by the use of the recycled aggregate. Therefore, this study suggests a bond strength prediction equation for the recycled aggregate replacement ratio and consequent compressive strength reduction.
FRP Rebar를 사용한 콘크리트 보의 효율적인 휨 설계를 위한 휨 강도감소계수 보정
심종성 ( Sim Jongsung ),박철우 ( Park Cheolwoo ),박명균 ( Park Myounggyun ),박성재 ( Park Sungjae ),김용재 ( Kim Yongjae ),박지수 ( Park Jisoo ) 한국구조물진단유지관리공학회 2008 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.12 No.2
If the flexural member of concrete is designed using the FRP rebar, suddenly brittleness destruction resulted from the fracture of FRP rebar is generated in the extreme situation because of brittleness characteristics of FRP rebar and concrete when designed to be less than balanced reinforcement ratio, so it is recommended to design the flexural member of concrete reinforced with FRP rebar to be more than balanced reinforcement ratio. In ACI 440.1R-06 proposes the different flexural strength reduction factor according to destructive form of concrete flexural member reinforced with FRP rebar. However, ACI 440.1R-06 applies the same flexural strength reduction factor to all FRP rebar made of diverse materials. If the same flexural strength reduction factor is applied to all FRP rebars, effect of increasing the reinforcement ratio and selection of FRP rebar will be considerably limited. In this regard, we are to propose the formula to calculate of flexural strength reduction factor in consideration of change in characteristics of FRP rebar through the reliability analysis in this paper.
Wireless pressure sensor integrated with a 3D printed polymer stent for smart health monitoring
Park, Jongsung,Kim, Ji-Kwan,Kim, Dong-Su,Shanmugasundaram, Arunkumar,Park, Su A,Kang, Sohi,Kim, Sung-Ho,Jeong, Myung Ho,Lee, Dong-Weon Elsevier 2019 Sensors and actuators. B Chemical Vol.280 No.-
<P><B>Abstract</B></P> <P>The primary objective of this study was to deploy a promising wireless pressure sensor system capable of monitoring real-time biological signals in an experimental object. MEMS-based micromachining technology was used to fabricate the proposed SU-8 wireless pressure sensor. The sensor utilizes a capacitor-inductor resonant circuit that can operate the sensor without any external power supply. The variable capacitor in the pressure sensor is designed to change the resonance frequency (130, 183 MHz) in response to applied pressure. The fabricated wireless pressure sensor was integrated into a polymer-based smart stent to minimize the discomfort of medication administration and hospital visits. A 3D bio-printing-based manufacturing technique was employed for the production of a smart polymer stent with complicated shapes. The proposed method is considerably more comfortable than the conventional metal stents fabrication process. The polymer smart stent made of the biocompatible polycaprolactone (PCL) material which can be fully absorbed by the body after a medication period. After integrating the fabricated wireless pressure sensor with the polymer smart stent, various basic experiments such as the working distance of the sensor were performed using a simple experimental setup. The biocompatibility of the proposed polymer stent and the wireless pressure sensor was also successfully confirmed using an experimental animal. The preliminary investigation results indicate that the proposed wireless sensor can be used to obtain necessary information in various parts of the human body as well as the stent.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Fabrication of SU-8 based wireless pressure sensor for battery-less operation. </LI> <LI> Manufacturing of biodegradable polymer stent using 3D printing technique. </LI> <LI> Integration of wireless pressure sensor into polymer stent for real-time blood pressure monitoring. </LI> <LI> Verification of the biocompatibility of smart stent and its operation with experimental animals. </LI> <LI> Continuous measurement of blood pressure change in animals for more than 3 months. </LI> </UL> </P>
Park, Sang Hee,Choi, Eunju,Kim, Sunggyu,Kim, Dong Sam,Kim, Ji Hyeon,Chang, SeokGu,Choi, Jae Seok,Park, Kyung Ja,Roh, Kyung-Baeg,Lee, Jongsung,Yoo, Byong Chul,Cho, Jae Youl MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.9
<P>Loliolide is a monoterpenoid hydroxylactone found in many algae, including fresh water green algae, <I>Prasiola japonica</I>. To date, loliolide and compounds in <I>P. japonica</I> have not been studied systematically with respect to skin pharmacology. In this study, we investigated oxidative stress-protective and anti-melanogenic effects of loliolide and <I>P. japonica</I> ethanol extract (Pj-EE), known to contain loliolide, in human keratinocyte (HaCaT) cells and mouse melanoma (B16F10) cells. Loliolide suppressed the transcription of genes encoding matrix metalloproteinases (MMPS), which were induced in HaCaT cells by hydrogen peroxide (H<SUB>2</SUB>O<SUB>2</SUB>) treatment. Loliolide and Pj-EE not only reduced the melanin secretion and content in B16F10 cells but also increased the expression of the antioxidant proteins nuclear factor (erythroid-derived 2)-like 2 (NRF2) and heme oxygenase-1 (HO-1) in HaCaT cells subjected to H<SUB>2</SUB>O<SUB>2</SUB> treatment. Furthermore, loliolide and Pj-EE decreased expression of the anti-melanogenic protein microphthalmia-associated transcription factor (MITF) and tyrosinase in B16F10 cells subjected to α-melanocyte-stimulating hormone (α-MSH) treatment. Our findings demonstrate that loliolide and Pj-EE have antioxidant and anti-melanogenic effects on skin.</P>
Profiling of miRNA expression in mice kidney with diabetic nephropathy
Park, Hye Rim,Lee, Seung Eun,Kim, Hyemi,Jeon, Seeun,Han, Dongkyo,Jin, Young-Ho,Cho, Jeong-Je,Ahn, Hyun-Jong,Park, Cheung-Seog,Lee, Jongsung,Park, Yong Seek THE KOREAN SOCIETY OF TOXICOGENOMICS AND TOXICOPRP 2018 MOLECULAR AND CELLULAR TOXICOLOGY Vol. No.