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( Jiong-jie Yu ),( Ju-dong Li ),( Xin-fei Xu ),( Zhen-li Li ),( Jun Han ),( Hao Xing ),( Han Wu ),( Jian-hong Zhong ),( Yi-sheng Huang ),( Ya- Hao Zhou ),( Ting-hao Chen ),( Hong Wang ),( Wei-min Gu ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: There is a striking sex difference in the incidence of hepatocellular carcinoma (HCC), with a strong predominance for males. However, the impact of sex on the incidence of recurrence after curative resection of HCC remains controversial. Herein, we assess sex differences in the risks of recurrence and mortality for patients undergone curative resection of HCC. Methods: Data from 1,435 HCC patients undergone curative resection (1,228 males and 207 females) between 2004 and 2014 at five institutions in China were retrospectively analyzed. Patients’ baseline characteristics, operative variables, and rates of early recurrence (≤ 2 years after resection), late recurrence (> 2 years) and cancer-specific mortality (CSM) were evaluated and compared. Multivariable competing-risks regression analyses were performed to identify predictors associated with CSM, early and late recurrence. Results: The early recurrence rates between males and females were similar (43.3% vs. 42.0%, P=0.728), but the late recurrence and CSM rates in males were higher when compared to females (17.2% vs. 11.2%, P=0.044; 42.8% vs. 34.3%, P=0.022). Multivariable competing-risks regression analyses revealed no sex difference in early recurrence; however, males had significantly higher late recurrence rate [hazard ratio (HR), 1.752; 95% CI, 1.145-2.682; P=0.010] and CSM rate (HR, 1.307; 95% CI, 1.015-1.683; P=0.038) than females. Conclusions: Males had significantly higher late recurrence and CSM rates after curative resection of HCC than females. This suggests postoperative surveillance for HCC recurrence be varied by sex, especially for patients without recurrence at 2 years after resection.
Jiong-feng Zhao,Tao-Wang,Jianping Lin,Lirong Yang,Mian-bin Wu 한국생물공학회 2019 Biotechnology and Bioprocess Engineering Vol.24 No.2
Early research on the nutritional value of 1,3- diacylglycerols (1,3-DAGs) has resulted in a significant interest in their synthesis. 1,3-DAGs can be produced chemically and biologically. In this work, a regioselective lipase from Rhizopus oryzae was efficiently immobilized on nanosized magnetite particles (NSM) in an oriented way, resulting in significant enhancement of activity. The specific hydrolytic and esterification activities of the immobilized enzyme were 1,660% and 260% of those of the free enzyme, respectively. The immobilized enzyme was then used to catalyze the esterification of oleic acid with glycerol in a solvent-free system for preparation of 1,3-DAG in a 1 L reactor. The catalytic process was studied in detail, the final concentration of 1,3-DAG reached >76% under the optimal condition when the molar ratio of oleic acid to glycerol was 2.8:1. The regioselectivities of free and immobilized enzyme were both >97%. The immobilized enzyme was reused for 55 cycles with only ~30% activity loss at 30ºC. The purity of 1,3-DAG was up to ~95% (w/w) after a simple purification step with the recovery ratio ~85%. This is the first report of efficient 1,3-DAG purification by neutralization without acyl migration.
Jiong-Feng Liang,En Wang,Qiao-Li Le 사단법인 한국계산역학회 2018 Computers and Concrete, An International Journal Vol.21 No.1
This paper presents the results of an experimental study to investigate the influences of high temperatures on the mechanical properties of concrete containing recycled fine aggregate. A total of 150 concrete prisms (100x100x100 mm) are cast and heated under five different temperatures (20oC, 200oC, 400oC, 600oC, 800oC ) for test. The results show that the mass loss, compressive strength, elastic modulus, splitting tensile strength of concrete specimens containing recycled fine aggregate decline significantly as the temperature rise. At the same temperature, the compressive strength, splitting tensile strength, elastic modulus of concrete specimens containing recycled coarse aggregate and recycled fine aggregate (RHC) is lower than that of concrete specimens containing natural coarse aggregate and recycled fine aggregate (RFC). The shape of stress–strain curves of concrete specimens at different temperatures is different, and the shape of that become flatter as the temperature rises. Normal concrete has better energy absorption capacity than concrete containing recycled fine aggregate.
Jiong Zhang,Yunhai Huang,Weidong Liu,Liankun Wang,Chao Yang,Lin Zuo 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.1
This paper presents a micromechanical method to analyze the thermal stresses in a finite plane containing multiple elliptical inclusions. Firstly, the Eshelby’s equivalent inclusion method is employed to solve the elastic fields of a two-dimensional infinite plane containing multiple elliptical inclusions under a uniform temperature change. Both the interior Eshelby’s tensor and the exterior Eshelby’s tensor are employed. Then the boundary of the plane is modeled by continuous distributions of dislocation densities. By combining the two steps, a system of singular integral equations is formulated based on the traction-free boundary condition. Then the thermal stresses of the plane can be obtained by the superposition of the stresses obtained by the Eshelby’s equivalent inclusion method and distributed dislocation method. Additionally, some examples are given to show the effects of the presented method. The effects of the material constants, geometric parameters and fiber packing arrangement on the thermal stresses are also studied.
Jiong Mo Cui,Ha Sook Chung,Won Sick Woo 한국생약학회 1994 생약학회지 Vol.24 No.4
A new method for separation and quantitative determination of isofiavone glucosides in rhizomes of Belamcanda chinensis (Iridaceae) by high performance liquid chromatography was elaborated. A reverse-phase system with a Spheri-5 RP-18 column using MeOH : HOAc : H₂O(24 : 5 : 71) as a mobile phase was developed. The isoflavonoids were detected at 268 ㎚ and the analysis was successfully carried out within 15 min.
Flexural behavior of partially prefabricated partially encased composite beams
Jiong-feng Liang,Liu-feng Zhang,Ying-hua Yang,Li Wei 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.38 No.6
An innovative partially precast partially encased composite beam (PPECB) is put forward based on the existing research. In order to study the flexural performance of the new composite beam which has precast part and cast-in-place part, six prefabricated specimens and one cast-in-place specimen are designed with considering the influence of the production method, the steel flange thickness, the concrete strength grade and the stirrup process on the behavior of the composite beam. Through four points loading and test data collection and analysis, the behavior of partially prefabricated specimen is similar to that of cast-in-place specimen, and the casting method, the thickness of the steel flange, the concrete strength grade and the stirrup process have different influence on the crack, yield and peak load bearing capacity of the component. Finally, the calculation theory of plastic bending of partially precast partially encased concrete composite beams is given. The calculation results are in good agreement with the experimental results, which can be used for practical engineering theory guidance. This paper can provide reference value for further research and engineering application.
Cyclic performance of concrete beams reinforced with CFRP prestressed prisms
Jiong-Feng Liang,Yu Deng,Minghua Hu,Dilian Tang 사단법인 한국계산역학회 2017 Computers and Concrete, An International Journal Vol.19 No.3
This paper describes an experimental study of the cyclic performance of concrete beams reinforced with CFRP prestressed concrete prisms (PCP). The failure modes, hysteretic loops, skeleton curve, ductility, energy dissipation capacity and stiffness degradation of concrete beams reinforced with CFRP prestressed concrete prisms were analyzed. The results show that The CFRP prestressed prisms reinforced concrete beams have good seismic performance. The level of effective prestress and cross section of CFRP prestressed prisms had a little influence on the bearing capacity, the ductility and energy dissipation capacity of CFRP prestressed prisms reinforced concrete beams.