P. 포스터세션 : P1~P9 서비스 품질/ 서비스 경영 ; P4 : 대기오염이 건강에 미치는 영향 연구

박진옥 ( Jin Ok Park ),윤상후 ( Sang Hu Woon ),나명환 ( Myung Hwan Na ),송호천 ( Ho Chun Song ),김자혜 ( Ja Hae Kim ),박진경 ( Jin Kyung Park ),옥유진 ( You Jin Ok ) 한국품질경영학회 2015 한국품질경영학회 학술대회 Vol.2015 No.1

전산화 인지재활(RehaCom)이 정신분열증 환자의 인지기능에 미치는 효과

송예원 ( Ye Won Song ),송아영 ( A Young Song ),강수진 ( Su Jin Kang ),송지연 ( Ji Yeon Song ),최희선 ( Hu Seon Choi ),전병진 ( Byeong Jin Jeong ) 대한인지재활학회 2015 대한인지재활학회지 Vol.4 No.1

목적: 정신분열증 환자에게 전산화 인지재활(RehaCom)을 실시하여 전산화 신경인지기능검사(Computerized neurocognitive function test; CNT)를 통해 그 효과를 살펴봄으로써 정신분열증환자의 작업치료 중재에서 인지재활에 대한 근거를 제시하고자 한다. 연구방법: 대전지역 시설에 거주하는 정신분열증 환자 20명을 실험집단 10명과 통제집단 10명으로 무작위 배정하였다. 실험 기간은 2011년 7월 20일부터 9월 9일까지 진행되었다. 실험 전 두 집단의 인지능력 기초선은 CNT를 통해 측정하였고, 전산화 인지재활을 사용한 중재는 실험집단의 경우 3주간 주 2회씩 총 6회 실시하였으며, 이 기간 동안 통제집단은 복지시설에서 이루어지는 프로그램에만 참여하였다. 모든 중재가 종료된 후 각 집단의 인지능력 향상 정도를 측정하였다. 두 집단 간 평균차이 검증을 위해서 독립표본 t검증과 실험 전후의 평균차이를 검증하기 위해서 짝비교 검증을 실시하여 중재가 인지능력에 변화에 미치는 효과를 검증하였다. 결과: 실험집단에서 전산화 인지재활 후 단기기억(Digit span test)과 집행기능(Card sorting test)에서 통계적으로 유의미하게 향상되었으며, 주의집중력은 통계적으로 유의미하지 않았다(p<.05). 결론: 정신분열증 환자에게 전산화 인지재활이 단기기억력과 집행기능의 향상에 효과적인 것으로 분석되어 향후 정신사회 작업치료에서 전산화 인지재활이 필요한 것으로 판단된다. Objective: This study tried to identify the effects of computerized cognitive rehabilitation(RehaCom) through Computerized neurocognitive function test(CNT) to schizophrenic patients by conducting computerized cognitive rehabilitation(RehaCom) and to suggest the basis for cognitive rehabilitation in occupational therapy intervention of schizophrenic patients. Methods: Study subject were targeting 20 schizophrenic patients and each 10 patients were randomly allocated in experiment group and control group. Experiment period was from 2011 July 20 to September 9. Cognitive function base lines in two groups before the experiment were measured by CNT and interventions using computerized cognitive rehabilitation were conducted total of 6 times for 3 weeks, 2 times a week in experiment group, and control group participated just in the programs executed in welfare facilities. After all interventions, cognitive function improvement levels in each group were measured. In order to test average differences between two groups, independent sample t-test was conducted and to test the average differences before and after the experiment, paired t-test was conducted and subsequently, the effects of intervention on cognitive function were tested. Result: In experiment group, short-term memory(Digit span test) and executive function(card sorting test) after computerized cognitive rehabilitation showed statistically significant improvement and attention concentration ability was not statistically significant. (p<.05). Conclusion: Computerized cognitive rehabilitation was identified to be effective to schizophrenic patients in the improvement of short-term memory and executive function and therefore, computerized cognitive rehabilitation is considered to be required in future psychosocial occupational therapy.

Subacute oral toxicity of Dendropanax morbiferus H.Lév leaf extracts in Sprague-Dawley rats

Jiyong Park(Jiyong Park),Chang-Soo Cho(Chang-Soo Cho),Jun-Ho Song(Jun-Ho Song),Kwang Il Park(Kwang Il Park),Yeung Bae Jin(Yeung Bae Jin),Woo Hyun Kim(Woo Hyun Kim),Suk Kim(Suk Kim),Hu-Jang Lee(Hu-Jang 한국예방수의학회 2023 예방수의학회지 Vol.47 No.1

This study examined the subacute oral toxicity of Dendropanax morbiferus H.Lév leaves hot-water extracts (DMWE) using male and female Spargue-Dawley rats. Rats were orally administered the DMWE at dose levels of 0, 250, 500, 1,000, and 2,000 mg/kg body weight (BW) for four weeks. For experimental period, clinical signs and the number of deaths were examined, and feed intake and BW of all experimental animals were measured once a week for four weeks. At the end of the experiment, blood samples were collected from all rats, and all animals were euthanized and autopsies were performed to collect major organs. No dead animals were found during the experimental period. In addition, no differences were found between control and DMWE-treated groups in feed intakes, BW changes, organ weights, clinical signs, hematological parameters, and serum biochemical parameters. The results of this study provided evidence that oral administration of DMWE at the dose of 2,000 mg/kg BW is safe in rats and may not exert severe toxic effects.

Acute oral toxicity of Dendropanax morbiferus H.Lév leaf extracts in ICR mice

Chang-Soo Cho(Chang-Soo Cho),Jiyong Park(Jiyong Park),Jun-Ho Song(Jun-Ho Song),Yeung Bea Jin(Yeung Bea Jin),Kwang Il Park(Kwang Il Park),Woo Hyun Kim(Woo Hyun Kim),Suk Kim(Suk Kim),Hu-Jang Lee(Hu-Jang 한국예방수의학회 2023 예방수의학회지 Vol.47 No.1

In this study, the acute toxicity of Dendropanax morbiferus H.Lév leaf hot-water extracts (DMWE) was examined in male and female ICR mice. Mice were orally administered the DMWE at dose levels of 0, 250, 500, 1,000 and 2,000 mg/kg body weight (BW) for single-dose toxicity test. There were no significant differences in change of BW between control and all DMWE treated-groups. In hematological and blood biochemical analysis, none of the parameters were affected by the DMWE. Similarly, there were no significant effects on markers for liver and kidney functions in all DMWE treated-groups. Since there were no adverse effects of the DMWE in single oral toxicity tests, even at the highest doses, it was concluded that the lethal dose 50 (LD50) of DMWE is estimated at > 2,000 mg/kg BW.

Optimal Rate Selection for Persistent Scheduling with HARQ in Time-Correlated Nakagami-m Fading Channels

Hu Jin,Changgi Cho,Nah-Oak Song,Dan Keun Sung IEEE 2011 IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS Vol.10 No.2

<P>Orthogonal frequency division multiple access (OFDMA) systems, such as IEEE 802.16e/m and 3GPP Long Term Evolution (LTE), require significantly large signaling overhead for delivering small-sized delay-sensitive traffic such as voice over IP (VoIP) service. It may result in a significant decrease in the spectral efficiency. In order to overcome this drawback, recently, a persistent scheduling scheme has been standardized in standard bodies. In order to reduce the signaling overhead, the modulation and coding scheme (MCS) is set to be fixed during a burst period for the persistent scheduling procedure and an incomplete transmission, if it occurs, is recovered by a hybrid automatic repeat request (HARQ) scheme. In this paper, considering the HARQ retransmissions, we propose a rate selection scheme for the persistent scheduling satisfying given quality of service (QoS) requirements. In our proposed rate selection scheme, we consider two important factors which were not considered in previous HARQ-related work: time-correlations of the wireless channel in the HARQ retransmissions and the resource usage of signaling overhead. Numerical results show that the proposed rate selection scheme can efficiently enhance the utilization of radio resources compared to the conventional schemes.</P>

Healing Effects of Rebamipide and Omeprazole in <i>Helicobacter pylori-</i>Positive Gastric Ulcer Patients after Eradication Therapy: A Randomized Double-Blind, Multinational, Multi-Institutional Comparative Study

Song, Kyung Ho,Lee, Yong Chan,Fan, Dai-Ming,Ge, Zhi-Zheng,Ji, Feng,Chen, Min-Hu,Jung, Hyun Chae,Bo, Jiang,Lee, Sang Woo,Kim, Jin-Ho S. Karger AG 2011 Digestion Vol.84 No.3

<P>Abstract</P><P><I>Background and Aims:</I> A recent placebo-controlled trial showed that rebamipide, which is a mucosal-protective antiulcer agent, promoted gastric ulcer healing without affecting the <I>Helicobacter pylori</I> status. We conducted a randomized, double-blind trial to compare the healing effects of rebamipide and the proton-pump inhibitor omeprazole in <I>H. pylori</I>-positive gastric ulcers after <I>H. pylori</I> eradication therapy. <I>Methods:</I> After completion of 1 week of eradication therapy, 132 patients with <I>H. pylori</I>-positive gastric ulcer were enrolled in 5 Chinese and 4 Korean institutions. Patients were randomly assigned to take either 20 mg of omeprazole (n = 63) or 300 mg of rebamipide (n = 65) daily for 7 weeks. Healing was defined as complete recovery and S1 and S2 stage ulcer according to the Sakita-Miwa classification. <I>Results:</I> Healing rates at 12 weeks were 81.5% (53/65) and 82.5% (52/63) in the rebamipide and omeprazole groups, respectively. There was no significant difference in treatment efficacy, as evidenced by gastric ulcer healing rates (absolute difference –1.0%; 95% confidence interval –10.7 to 8.7; p = 0.88). The <I>H. pylori</I> eradication rate and ulcer healing rate did not differ between the groups, the latter regardless of eradication outcome. <I>Conclusions:</I> Rebamipide is as effective as omeprazole in treating of <I>H. pylori</I>-positive gastric ulcer after eradication therapy.</P><P>Copyright © 2011 S. Karger AG, Basel</P>

Effectiveness of alendronate as an adjunct to scaling and root planing in the treatment of periodontitis: a meta-analysis of randomized controlled clinical trials

Jin Chen,Qian Chen,Bo Hu,Yunji Wang,Jinlin Song 대한치주과학회 2016 Journal of Periodontal & Implant Science Vol.46 No.6

Purpose: Alendronate has been proposed as a local and systemic drug treatment used as an adjunct to scaling and root planing (SRP) for the treatment of periodontitis. However, its effectiveness has yet to be conclusively established. The purpose of the present meta-analysis was to assess the effectiveness of SRP with alendronate on periodontitis compared to SRP alone. Methods: Five electronic databases were used by 2 independent reviewers to identify relevant articles from the earliest records up to September 2016. Randomized controlled trials (RCTs) comparing SRP with alendronate to SRP with placebo in the treatment of periodontitis were included. The outcome measures were changes in bone defect fill, probing depth (PD), and clinical attachment level (CAL) from baseline to 6 months. A fixed-effect or random-effect model was used to pool the extracted data, as appropriate. Mean differences (MDs) with 95% confidence intervals (CIs) were calculated. Heterogeneity was assessed using the Cochrane χ2 and I2 tests. Results: After the selection process, 8 articles were included in the meta-analysis. Compared with SRP alone, the adjunctive mean benefits of locally delivered alendronate were 38.25% for bone defect fill increase (95% CI=33.05%–43.45%; P<0.001; I2=94.0%), 2.29 mm for PD reduction (95% CI=2.07–2.52 mm; P<0.001; I2=0.0%) and 1.92 mm for CAL gain (95% CI=1.55–2.30 mm; P<0.001; I2=66.0%). In addition, systemically administered alendronate with SRP significantly reduced PD by 0.36 mm (95% CI=0.18–0.55 mm; P<0.001; I2=0.0%) and increased CAL by 0.39 mm (95% CI=0.11–0.68 mm; P=0.006; I2=6.0%). Conclusions: The collective evidence regarding the adjunctive use of alendronate locally and systemically with SRP indicates that the combined treatment can improve the efficacy of non-surgical periodontal therapy on increasing CAL and bone defect fill and reducing PD. However, precautions must be exercised in interpreting these results, and multicenter studies evaluating this specific application should be carried out.

Location of the Infraorbital and Mental Foramen with Reference to the Soft-Tissue Landmarks

Song, Wu-Chul,Kim, Sun-Heum,Paik, Doo-Jin,Han, Seung-Ho,Hu, Kyung-Seok,Kim, Hee-Jin,Koh, Ki-Seok American Society of Plastic Surgeons 2007 Plastic and reconstructive surgery Vol.120 No.5

BACKGROUND:: The purpose of the present study was to determine the locations of the infraorbital foramen and mental foramen based on soft-tissue landmarks to facilitate prediction of the locations of these structures during facial surgery. METHODS:: Fifty embalmed cadavers (100 sides) of Koreans were dissected to expose the infraorbital foramen and mental foramen. The distances between the bilateral infraorbital foramina and between the mental foramina and the distances between the alae of the nose and between the corners of the mouth (cheilions) were measured directly on the cadavers, and the vertical and horizontal distances between the infraorbital foramen and mental foramen and the ala of the nose and cheilions, respectively, were measured indirectly on photographs. RESULTS:: The distance between the bilateral infraorbital foramina (54.9 ± 3.4 mm) was greater than that between the bilateral mental foramina (47.2 ± 5.5 mm). The infraorbital foramen was located 1.6 ± 2.7 mm lateral and 14.1 ± 2.8 mm superior to the ala of the nose. The distance between the ala of the nose and the infraorbital foramen was 15.9 ± 2.8 mm, and the horizontal angle between these structures was 64.1 ± 9.9 degrees laterosuperiorly. The mental foramen was located 20.4 ± 3.9 mm inferior and 3.3 ± 2.9 mm medial to the cheilions. The distance between the cheilions and mental foramen was 20.9 ± 3.8 mm, and the vertical angle between these structures was 9.2 ± 8.1 degrees inferomedially. CONCLUSIONS:: This study provides data that will be useful in predicting the locations of the infraorbital foramen and mental foramen when used together with hard-tissue landmarks. These data may be particularly helpful for facial surgery in patients with missing teeth.

Celiac Axis and Common Hepatic Artery Variations in 5002 Patients: Systematic Analysis with Spiral CT and DSA.

Song, Soon-Young,Chung, Jin Wook,Yin, Yong Hu,Jae, Hwan Jun,Kim, Hyo-Cheol,Jeon, Ung Bae,Cho, Baik Hwan,So, Young Ho,Park, Jae Hyung Radiological Society of North America 2010 Radiology Vol.255 No.1

<P>Purpose: To identify and evaluate the spectrum and prevalence of celiac axis (CA) and common hepatic artery (CHA) variations by using spiral computed tomography (CT) and digital subtraction angiography (DSA). Materials and Methods: Institutional review board approval was obtained, and the requirement for informed patient consent was waived. The findings in 5002 patients who underwent spiral CT and DSA were retrospectively evaluated. CHA was defined as an arterial trunk containing at least one segmental hepatic artery and the gastroduodenal artery. The pattern of the aortic origin of the branches of the CA and superior mesenteric arteries was analyzed. The CHA anatomy was then investigated. Results: Of 15 possible types of CA variation, 13 types were identified. A normal CA was noted in 4457 (89.1%) of the 5002 patients. Twelve types of CA variation were identified in 482 (9.64%) patients. In the remaining 63 (1.26%) patients, the CA anatomy was classified as ambiguous because the CHA was absent owing to separate origins of the hepatic arteries and the gastroduodenal artery (n = 55) or because the origin of the CHA could not be determined owing to persistent anastomotic channels (n = 8). Seven CHAs originating from the normal CA had a retroportal (n = 6) or transpancreatic (n = 1) course. All eight CHAs originating from the left gastric artery passed the fissure of the ligamentum venosum. The 148 CHAs originating from the superior mesenteric artery showed diverse relationships with the pancreas-being supra-, trans-, or infrapancreatic-and the superior mesenteric-portal venous axis-being pre- or retroportal. The 20 CHAs originating from the aorta had a normal suprapancreatic preportal course. Conclusion: Known or newly found CA and CHA variations could be systematically described in detail. The authors propose a hypothetical anatomic model for summarizing the observed CHA variations. (c) RSNA, 2010 Supplemental material: http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.09090389/-/DC1.</P>

Female-to-Male Proportions of the Head and Face in Koreans

Song, Wu-Chul,Kim, Jung-Il,Kim, Soon-Heum,Shin, Dong-Hyeok,Hu, Kyung-Seok,Kim, Hee-Jin,Lee, Jeong-Yong,Koh, Ki-Seok Mutaz B. Habal, MD 2009 JOURNAL OF CRANIOFACIAL SURGERY - Vol.20 No.2

It is well known that the head and face are smaller in female subjects than in male subjects. However, almost all previous studies have quantified the size difference between female and male subjects as simple numerical values, which might not clarify the difference. The present study evaluated the female-to-male proportions of the head and face so as to clarify the sex-related differences. A total of 1939 female subjects and 1398 male subjects were divided into 3 age groups: young (20-39 y), middle-aged (40-59 y), and elderly (60-79 y). The dimensions were classified into 3 categories: 5 cephalic, 3 frontal facial, and 6 lateral facial. The female-to-male proportions of individual dimensions were compared in the 3 age groups using the following formula: female measurement value × 100/(mean of male measurement value). The female-to-male proportions of the cephalic dimension increased with age, with the female cephalic dimensions overall being about 96% of the male cephalic dimensions. The female-to-male proportions of the frontal facial dimension were constant across the age groups, with the female frontal facial dimensions overall being 95% of the male frontal facial dimensions. The female lateral facial dimension increased markedly from the young to middle-aged group and was constant or decreased slightly from the middle-aged to the elderly group. Overall, the female lateral facial dimensions were approximately 97% of the male lateral facial dimensions. The present study will suggest a new approach to elucidate those sex-related dimensional differences that are characteristic of female and male subjects.