Temporal trends of the prevalence and incidence of atrial fibrillation and stroke among Asian patients with hypertrophic cardiomyopathy: A nationwide population-based study

Choi, You-Jung,Choi, Eue-Keun,Han, Kyung-Do,Jung, Jin-Hyung,Park, Jiesuck,Lee, Euijae,Choe, Wonseok,Lee, So-Ryoung,Cha, Myung-Jin,Lim, Woo-Hyun,Oh, Seil Elsevier 2018 INTERNATIONAL JOURNAL OF CARDIOLOGY Vol.273 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Atrial fibrillation (AF) and stroke are common in hypertrophic cardiomyopathy (HCM). We aimed to determine the prevalence and incidence of AF and stroke in patients with HCM during a 10-year period.</P> <P><B>Methods</B></P> <P>Using the Korean National Health Insurance Services database, we identified patients diagnosed with HCM from the entire Korean population between 2005 and 2015. The annual prevalence and incidence of AF and stroke in HCM patients were estimated.</P> <P><B>Results</B></P> <P>The prevalence of AF in HCM patients has gradually increased to 1.6-fold from 13.4% in 2005 to 20.9% in 2015. The incidence of AF ranged from 4.1 to 5.5%, a similar trend was observed for each year in HCM patients. The prevalence of stroke in HCM patients was approximately 10%, while that in HCM patients with AF was about 20%. During 8741 person-years, AF-related stroke occurred in 257 subjects among 2309 HCM patients with new-onset AF. The overall incidence rate of AF-associated stroke was 2.94 per 100 person-years. In subgroup analysis, the incidence rate of AF-associated stroke was 1.49 per 100 person-years in the under 45 year-old group and 1.48 per 100 person-years in the group with CHA<SUB>2</SUB>DS<SUB>2</SUB>­VASc score of 0 or 1 point in HCM patients.</P> <P><B>Conclusions</B></P> <P>The prevalence of AF in HCM patients gradually increased over 10 years. The annual risk of AF-associated stroke in HCM was over 1% even in younger patients and those with CHA<SUB>2</SUB>DS<SUB>2</SUB>­VASc score of 0 or 1 point, which provide evidence to support the prevention of stroke in HCM patients with AF.</P> <P><B>Highlights</B></P> <P> <UL> <LI> This is the first largest nationwide study on hypertrophic cardiomyopathy (HCM), a rare myocardial disease in Korea. </LI> <LI> The prevalence of AF in HCM patients gradually increases to 1.6-fold from 13.4% in 2005 to 20.9% in 2015. </LI> <LI> The annual incidence of AF in HMC patients was about 5%, and higher in female and the elderly. </LI> <LI> The prevalence of stroke in HCM patients with AF was about 20%, which were more than twice that in overall HCM patients. </LI> <LI> The risk of AF-related stroke in HCM patients was >1% per person-year even in younger patients or low CHA<SUB>2</SUB>DS<SUB>2</SUB>­VAS<SUB>C</SUB> score. </LI> </UL> </P>

급식위탁경영에 대한 고찰 연구

차진아,이경자 기전여자대학 1994 論文集 Vol.14 No.-

The purpose of this study is to : a) review the recent state of contracted management for foodservice facilities in Korea and foreign countries, b) compare the advantage and disadvantage of contract management. In US, Japan and other foreign countries, contracted foodservice management companies are very large enterprises. Their sales dollar have shown tremendous increase for recent years. These agencies contract with foodservice in hospital, school and many business firms and operate the foodservice facilities instead of these institutions. In Korea, several foodservice management agencies contracted with some hospital and business firms, and the more foodservice in institutions will introduce contracted management. The advantages of contracting are the more professional and effective management performed by agencies. They operate multi-unit systems and supply raw food materials with large scales and low price. They can effectively work with the automatic machines and facilities and computerized systems. But contracted management also have many disadvantages. first of all, management agency can make trouble with the contracted institutions. Although mutual cooperation between management agency and contracted institution is essential for each other, management agency operates foodservice for the profit, so especially in hospital dietetic department patient service can be neglected. As a conclusion, before the determining for contract management, foodservice institutions completely examine advantages and disadvantages for the contracting, and select the agency by systematic steps and processes.

양수 다발성 수지 재접합수의 치험례 : 4 cases report

차진한,박명철,김우경,한근태,김수신,백세민 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.2

Since the first successful replantation operation, several reports have been recorded replantated finger survival with high success rates. But ten and nine digits amputations are not common. It is even more unusual to have all digits suitable for replantation. 4 cases are presented where replantation of ten and nine digits were done at the department of PRS. Guro Hospital, Korea University from March 1987 to Jun 1988. In these cases, the patients were young and healthy, all of ten and nine digits were sharply amputed near the proximal phalanx, so a replantation team of 8 surgeons in alternating fashion replanted all ten and nine digits over 30 hours and each patient received 28 pints of whole blood during the procedure. Under general anesthesia, replantatin of both started simultaneously. All digits survived completely except partial necosis of right little finger in case 1. The ischemic time of each digit ranged from 4 hours and 45 minutes to 31 hours as shown in table 5. The long ischemic time did not criticaly affected the survival of amputated digit. Follow-up was from 12 months to 20 months postoperatively. The functional evaluation revealed as follows: 1. The grasping power ranged 13 lb to 65 lb(average;39.7lb) 2. The pinching power with index finger ranged 5 lb to 15 lb(average:10.2 lb) 3. The palm to pulp distance ranged 0 cm to 6 cm.(average;2.2cm) 4. The two point discrimination ranged 2.5mm to 22mm.(average;7.8mm) 5. The shape of digits were acceptable aesthetically. 6. All 4 patients were able to use both hands well in all activities of daily living.

중앙대학교 사범대학과 부속학교의 연계성 연구

차경환,나항진 中央大學校 韓國敎育問題硏究所 1998 韓國敎育問題硏究所論文集 Vol.- No.13

선천성 톡소플라스마증(Taxoplasmosis)의 실험적 연구

車錫奎,任敬一,李根泰,尹德鎭 연세대학교 의과대학 1982 연세의대논문집 Vol.15 No.1

사람, 토끼 및 기니픽 이자섬에서의 아밀린의 면역반응성

김성경,김영희,차정호,김진,정진웅 대한해부학회 1997 Anatomy & Cell Biology Vol.30 No.4

非定常熱源加熱法에 依한 迅速熱物性値測定에 關한 硏究

車京玉,李眞 明知大學校 産業技術硏究所 1985 産業技術硏究所論文集 Vol.4 No.-

Theoretical and experimental studies were made on unsteady heat source heating method of measuring thermal properties of a small solid disk. The disk is placed in three point support and heated on the front face by thermal radiation whose intensity is varied in exponential heat pulse by a mechanical shutter. The temperature of the rear face in measured by thermocouples and recorded on oscillograph. On the basis of its data thermal diffusivity is calculated by taking the thermal ration in different times. In the present work thermophysical properties of alloy tool steels and structual carbon steels were measured in temperature 293K by this method. The thermal diffusivity and thermal conductivity in thermophysical properties of the sample material is then determined using a data reduction excursion method by computer from the recorded transient temperature versus time curve. For the improvement of accuracy in determing the thermophysical properties of sample by unsteady heat source heating method, the solution of governing heat transfer equation with the finite pulse time effect and with the heat loss on sample surface is obtained through an integral transform method. In order to computer the thermal conductivity of the standard pieces, their specific heat are measured by a differential scanning calorimeter. The thermal conductivity are calculated from the data such as specific heat, density, thermal capacity and thermal diffusivity. In the measurements it was made clear that this method can be successfully adopted to measure thermophysical properties of solid in considerabley short time and with high accuracy up to higher temperature or very lower temperature.

두부방사선 분석에 의한 상악전치부 후방이동시 연조직 변화 예측에 대한 연구

최진희,이진우,차경석 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.1

본 연구는 성장에 의한 효과를 배제한 교정치료시의 연조직 변화와 치아 및 악골의 수평적, 수직적 움직임과의 상관 관계를 알아보고 예측 가능성을 검토하기 위해 Angle씨 2급 부정교합 환자 41명을 대상으로 치아 및 악골, 연조직의 수평, 수직이동의 평균 변화량을 측정하고 연조직에 대한 계단식 다중 회귀분석을 시행하였으며 다음과 같은 결론을 얻었다. 1. 경조직 계측항목 중 상악 중절치의 수평이동 및 기울기, 하악 중절치의 수평 및 수직이동, 수평피개량, 수직피개량, interincisal angle, 하악골 위치 변화 A, B, 경조직 측모 돌출각 등의 항목에서, 연조직 계측항목 중 상순의 두께 및 후방이동, 기울기, 하순의 후방이동 및 기울기, interlabial angle, 비순각, 이순각, Sn, Ss, Si, 연조직 측모 돌출각 등의 항목에서 치료 전과 후에 유의성 있게 변하였다(P<0.05). 2. 치료 전 후 유의한 변화를 보인 연조직 계측항목을 분석한 결과 모든 항목에서 경조직의 변화에 대해 영향을 받는 것으로 나타났다(P<0.05). 3. 연조직 회귀방정식에 중절치 수평피개량, 상악 전치 절단연의 후방이동량, 상악 전치 치근의 후방이동량, Pg의 수평변화량이 가장 높은 빈도로 포함됨으로써 이들은 연조직의 수직 및 수평변화에 영향을 많이 미치는 요소로 나타났으며 하악 전치의 수직이동량은 포함되지 않음으로써 연조직 변화와 관련성이 적은 것으로 나타났다. 4. Sn의 수직 및 수평변화는 경조직의 가장 많은 항목과 연관됨으로써 (A, B, Pg(H), overjet, upper incisor angle, Ur, Is(H)) 여러 경조직 변화의 복합적인 영향을 받는 것으로 나타났다. 5. 연조직 계측항목에 대한 상관계수(R2)의 범위는 0.2-0.6으로 중등도의 상관정도를 나타내었다. This study was carried out in order to determine soft tissue response to incisor movement and mandibular repositioning and to determine feasibility of predicting vertical and horizontal changes in soft tissue with hard tissue movement. For this study, cephalometric records of 41 orthodontically treated adult females who had Angle`s Class II division 1 malocclusion were selected and stepwise multiple regression analysis was employed. Following conclusions were obtained by analysing the changes of soft tissue and hard tissue before and after treatment. 1. Hard tissue measurements that showed significant changes before and after treatment were horizontal and angular changes of maxillary incisor, horizontal, vertical and angular changes of mandibular incisor, overjet, overbite, interincisal angle, mandibular repositioning, A, B, skeletal convexity and soft tissue measurements that showed significant changes were horizontal, thickness and angular changes of upper lip, horizontal and angular changes of lower lip, interlabial angle, nasolabial angle labiomental angle, Sn, Ss, Si and soft tissue convexity(P<0.05). 2. All Soft tissue measurements changed significantly before and after treatment had between one and four hard tissue independent variables at statistically significant level, indicating that all soft tissue changes were direct relationship with hard tissue changes. 3. Overjet, horizontal change of maxillary incisor, horizontal change of maxillary root apex and horizontal change of pogonion entered into prediction equations most frequentely, indicating that they were more significant variables in prediction of vertical and horizontal changes in the soft tissue with treatment, but vertical changes of mandibular incisor not entered any prediction equations, indicating that it was not considered a good predictor for soft tissue changes with maxillary incisor retraction. 4. Horizontal and vertical changes in subnasale were found to have most independent variables, significant at the 0.05 level in prediction equations(△Sn(H):Ur, Is(H), Pg(H), UIA, △Sn(V): Is(H), Pg(H), overjet, A), indicating that subnasale changes are influenced by complex hard tissue interaction. 5. Multiple correlation coefficient(R2) of the soft tissue prediction equations ranges from 0.2-0.6.

EEPS 및 Cavity 회전형 희석장치를 이용한 디젤 입자의 입경 분포 연구

金鎭玄,李俊瑞,車京玉 明知大學校 産業技術硏究所 2006 産業技術硏究所論文集 Vol.25 No.-

EEPS is a newly introduced instrument for size distribution measurement of engine exhaust particles. It can measure nano-particles with an adequate resolution and in real time. In this study, the characteristics of EEPS were compared with ELPI and SMPS. EEPS showed a same effect of engine load on the size distribution with ELPI and SMPS. But the quantitative results of EEPS weremore similar to SMPS than ELPI, because the EEPS and SMPS use a same principle for classifying particles by size. The capability for transient measurement of EEPS was equivalent to that of ELPI. Additionally, the effects of dilution ratio and heating the dilution gas on the size distribution of the diesel particles werestudied using a rotating cavity type diluter.

정상 교합을 나타내는 한국인 성인의 EMG 특성에 관한 연구

이진우,차경석 단국대학교 치의학연구소 1994 논문집 Vol.6 No.1

The purpose of this study was to find out the muscle activity characteristics in normal occlusion subjects. Electromyographic recordings were made during resting and clenching periods in 28 adult male and female subjects, and following conclusions were reached. 1. No difference in all resting, clenching EMG was noted between male and female group. 2. When left and right groups were compared ,resting activity in Temporalis Anterior, Masseter, Temporalis Posterior were higher in right groups and Anterior belly of digastric muscle was higher in left groups. No difference in muscle activity was noted during clenching period. 3. When anterior and posterior temporalis muscles were compared, posterior showed more activity during resting period and anterior showed more activity during clenching period. 4. When minimum and maximum groups were compared, no significant difference were observed resting activities but significant difference were observed in clenching activity , indicating that maximum group have wider range of activity.