Distribution of Bi–MnS Inclusions Existing in 1215MS Steels: Correlation with Thermal Physical Coefficient

Jian‑bo Xie,Bei‑bei Liu,Xiang‑yu Wu,Jian‑xun Fu 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.5

This work aims to comprehensively summarize the types and distribution of the isolated Bi particles and MnS inclusions inthe Bi-bearing steels, to study the precipitated behavior of sulfide, and to study the effect of Bi particles on grain sizes andthe volume thermal expansion coefficients of the steels. Results show that the average percentage of the isolated Bi particles,semi-encapsulation, complete encapsulation, back-bridge, tiny encapsulation, cavity bridge Bi–MnS inclusions in the Bibearingsteels was 16.89%, 20.49%, 3.44%, 16.89%, 31.63%, 10.66%, respectively. The average equivalent diameters of thegrains in the 0 ppm, 130 ppm, 240 ppm, 760 ppm, 1200 ppm and 2300 ppm Bi content steels were 20.88, 20.17, 19.54, 18.13,13.98 and 13.25 μm, respectively. The precipitated equilibrium mass concentration product of the MnS (w[Mn]·w[S]) wascalculated to be 1.07, and the solid fraction fS value was 0.61. At 950 °C, the volume thermal expansion coefficient change(ΔVE) in 760 ppm Bi content steel was minimum 4 × 10–10%, while at 461.6 °C the ΔVE was maximum, 0.09%, which meansthat Bi affected the volume thermal expansion of the steel strongest in this temperature range.

Study on Patent Forewarning Evaluation Index System of High & New Technology Enterprises

Wu Jian-long,Wang Hong-qi,Tao Wei-wei 인하대학교 정석물류통상연구원 2009 인하대학교 정석물류통상연구원 학술대회 Vol.2009 No.10

In the era of knowledge economy, patent technology is the key factor for high and new technology enterprises to participate in the global competition and maintain continually competitive advantage, meanwhile, monopoly rent and innovation rent of patent technology is also suffered from the challenge of profession technology change and patent strategy of competitors. Thus, regarding patent risk factors of hight and new technology enterprises, the paper constructs patent forewarning evaluation index which involves four aspects of patent protection, quantity, quality and industrialization level, and proposes using tactics of the evaluation index during the enterprises patent forewarning, so as to provide method support for high and new technology enterprises to operate their patent forewarning mechanism effectively.

Modal Analysis of Resonance and Stable Domain Calculation of Active Damping in Multi-inverter Grid-connected Systems

Wu, Jian,Chen, Tao,Han, Wanqin,Zhao, Jiaqi,Li, Binbin,Xu, Dianguo The Korean Institute of Power Electronics 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.1

Interaction among multiple grid-connected inverters has a negative impact on the stable operations and power quality of a power grid. The interrelated influences of inverter inductor-capacitor-inductor filters constitute a high-order power network, and consequently, excite complex resonances at various frequencies. This study first establishes a micro-grid admittance matrix, in which inverters use deadbeat control. Multiple resonances can then be evaluated via modal analysis. For the active damping method applied to deadbeat control, the sampling frequency and the stable domain of the virtual damping ratio are also presented by analyzing system stability in the discrete domain. Simulation and experimental results confirm the efficiency of modal analysis and stable domain calculation in multi-inverter grid-connected systems.

CTNNB1 Mutation in Aldosterone Producing Adenoma

Jian-Jhong Wang,Kang-Yung Peng,Vin-Cent Wu,Fen-Yu Tseng,Kwan-Dun Wu 대한내분비학회 2017 Endocrinology and metabolism Vol.32 No.3

Discoveries of somatic mutations permit the recognition of subtypes of aldosterone-producing adenomas (APAs) with distinct clinical presentations and pathological features. Catenin β1 (CTNNB1) mutation in APAs has been recently described and discussed in the literature. However, significant knowledge gaps still remain regarding the prevalence, clinical characteristics, pathophysiology, and outcomes in APA patients harboring CTNNB1 mutations. Aberrant activation of the Wnt/β-catenin signaling pathway will further modulate tumorigenesis. We also discuss the recent knowledge of CTNNB1 mutation in adrenal adenomas.

Resonance Characteristics Analysis of Grid-connected Inverter Systems based on Sensitivity Theory

Jian Wu,Wanqin Han,Tao Chen,Jiaqi Zhao,Binbin Li,Dianguo Xu 전력전자학회 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.3

Harmonic resonance exists in grid-connected inverter systems. In order to determine the network components that contribute to harmonic resonance and the composition of the resonant circuit, sensitivity theory is applied to the resonance characteristic analysis. Based on the modal analysis, the theory of sensitivity is applied to derive a formula for determining the sensitivities of each network component parameter under a resonance circumstance that reflects the participation of the network component. The solving formula is derived for both parallel harmonic resonance and series harmonic resonance. This formula is adopted to a 4-node grid-connected test system. The analysis results reveal that for a certain frequency, the participation of parallel resonance and series resonance are not the same. Finally, experimental results demonstrate that the solving formula for sensitivity is feasible for grid-connected systems.

Stem Cell-Derived Exosomes: A New Method for Reversing Skin Aging

Wu Jinyan,Wu Sai-Nan,Zhang Li-Ping,Zhao Xiansheng,Li Yue,Yang Quyang,Yuan Ruoyue,Liu Jian-Lan,Mao Hong-Ju,Zhu Ningwen 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.5

Senescence is an inevitable natural life process that involves structural and functional degeneration of tissues and organs. Recently, the process of skin aging has attracted much attention. Determining a means to delay or even reverse skin aging has become a research hotspot in medical cosmetology and anti-aging. Dysfunction in the epidermis and fibroblasts and changes in the composition and content of the extracellular matrix are common pathophysiological manifestations of skin aging. Reactive oxygen species and matrix metalloproteinases play essential roles in this process. Stem cells are pluripotent cells that possess self-replication abilities and can differentiate into multiple functional cells under certain conditions. These cells also possess a strong ability to facilitate tissue repair and regeneration. Stem cell transplantation has the potential for application in anti-aging therapy. Increasing studies have demonstrated that stem cells perform functions through paracrine processes, particularly those involving exosomes. Exosomes are nano-vesicular substances secreted by stem cells that participate in cell-to-cell communication by transporting their contents into target cells. In this chapter, the biological characteristics of exosomes were reviewed, including their effects on extracellular matrix formation, epidermal cell function, fibroblast function and antioxidation. Exosomes derived from stem cells may provide a new means to reverse skin aging.

Current and power quality multi-objective control of virtual synchronous generators under unbalanced grid conditions

Wu, Jian,Liu, Tong,Qiu, Tianyi,Xu, Dianguo The Korean Institute of Power Electronics 2020 JOURNAL OF POWER ELECTRONICS Vol.20 No.2

In recent years, with the large-scale application of distributed power sources in the power grid, the power grid is moving toward low inertia and low damping. The virtual synchronous generator (VSG) has become a hot topic for scholars since it can simulate the moment of inertia, damping and frequency modulation of synchronous generators. Due to its unbalanced load distribution and the random variation of power loads, grid voltage is asymmetrical. Under grid voltage asymmetry, a VSG experiences output current imbalance and power oscillation. The grid current imbalance further reduces the transformer's three-phase voltage, which makes it unequal, cyclic, and very easy to cause electricity accidents. Aiming at this problem, this paper proposes three modes of current balance, reactive power balance and active power balance without changing the characteristics of VSGs. The output current balance and power are constant when the grid voltage is asymmetrical. The effectiveness and feasibility of the control strategy are verified by simulation and experimental results, which provides an effective scheme for balanced and stable operation of the grid.

The Prediction Research of Population Density Based on Deep Learning in Grain Stored Insects

Wu Jian-Jun,Dang Hao,Li Miao,Sun Fu-Yan,Zhu Yu-Hua,Zhen Tong,Zou Bing-Qiang 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10

Precision of pests, in stored grain insect population density, has been a hot and difficult research in pest detection and control system. The accuracy of prediction of pest density will directly affect to warehouse grain temperature and the food quality etc. In order to improve the accuracy, the paper which using the depth study method, established an insects density prediction mode with the depth of the belief network as the core. The model is applied to the algorithm of deep learning predictive control. According to the temperature and humidity of the grain obtained from the actual measurement and the initial density of the pest, we predicted the pest density. Simulation results show that the root mean square error is small between the predictive value and actual value, high prediction accuracy. The deep learning algorithm is applied to the population density of pests is effective.

Differentiating Technique: Constructing Efficient HIBE with Constant Size Ciphertext and Authorized Delegation

Jian-Wu Zheng,Jing Zhao,Xin-Ping Guan 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.8

As Hierarchical Identity Based Encryption (HIBE) system usually maps the true institutional structure of an organization or entity relationship between objects in real world, It is important that computation & communication complexity of private key, ciphertext, cryptographic computations and so on related to an entity in the hierarchy is independent to the hierarchy depth of the entity. Moreover, key escrow problem that any non-leaf entity in a hierarchical identity based cryptosystem can derive private keys for its descendants with use of its private key should be resolved, in order to prevent any entity from behaving on behalf of its descendants. In this paper, a new technique is introduced for composing a private key for each individual entity in HIBE system by differentiating between non-local identifiers and local identifiers of the identity of the entity. That we call Identifier Discrimination. With the technique, A selective identity secure HIBE system is constructed under Decisional Bilinear Diffie-Hellman (DBDH) assumption without using random oracles, where the private key and the ciphertext consist of constant number of group elements, and decryption requires only three bilinear map computations, regardless of the identity hierarchy depth. Moreover, in contrast to previous HIBE constructions, where private key for an entity can be derived by its ancestors with direct use of their private keys, key escrow problem inherent in identity based cryptosystems is resolved in our HIBE construction. Privilege of deriving private keys for an entity can be delegated to any of its ancestors through authorization by distributing specifically crafted values to the ancestor in our HIBE system, that we call Authorized Delegation.

Inhibitory Effect of Curcumin on Invasion of Skin Squamous Cell Carcinoma A431 Cells

Wu, Jian,Lu, Wen-Ying,Cui, Lei-Lei Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

Objective: To investigate the regulatory effect of curcumin on expression of signal transducer and activator of transcription 3 (STAT3) in skin squamous cell carcinoma tissues as well as possible mechanisms of curcumin in prevention and treatment of skin squamous cell carcinoma. Materials and Methods: Highly invasive A431 cells were treated with curcumin at various doses .The cytotoxic effects of treatment with 5, 10, 15, 20, 25, 30, 35, 40 and 50 umol/L curcumin for 24, 48 and 72 hours on A431 cells were measured by MTT assay. The invasion capacity of cells treated with 5, 10 and 15 umol/L curcumin was measured by Transwell test, while adhesive ability was assessed by cell adhesion assay. The effects of 5,10 and 15 umol/L curcumin on expression levels of STAT3 were determined by Western blotting and on transcription levels of STAT3 mRNA by RT-PCR. Results: Treatment with curcumin at a doses of more than 15 umol/L for more than 24 hour inhibited the growth of A431 cells in a time-and dose-dependent fashion (p<0.001). The doses of 15 umol/L and less for 24 hours showed no significant cytotoxic effects on the cells, survival rates being more than 85%.The invasion and adhesive abilities decreased gradually with the increasing curcumin concentration, 15 umol/L exerting the strongest inhibitory effects (p<0.05). Curcumin showed significant dose-dependent inhibitory effects on the transcription level of STAT3 mRNA (p<0.05). Conclusions: Curcumin may reduce the invasive ability of A431 cells by inhibiting the activation of STAT3 signal pathway and expression of STAT3 as a target gene in the pathway.