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Jiali Cai,Guochuang Chen,Rongrong Jin,Changhui Deng,Shihui Huang,Xuexia Yuan,Gengjia Chen,Jing Zhao,Zhiyong Wang,Hua Ai 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.76 No.-
Due to the tumor immune escape mechanism, strategies like the utilization of bispecific antibodies wereused to assist immunotherapy. Herein a visible polymer–inorganic hybrid gene vehicle had beenprepared to deliver anti-EpCAM/anti-CD3 encoding minicircle DNA into normal cells thus thesetransfected cells effectively secreted bispecific antibody with bioactivity. In the experiments, thiscompound system exhibited excellent biocompatibility, high transfection efficiency and ultrasensitiveimaging capacity. Furthermore, the transfected cells could be detected under the MR imaging system andthe gene product showed an outstanding immune effect. In conclusion, this nanocomposite showedsynergistic advantages in gene delivery and non-invasive MR imaging.
Song, Jiali,Li, Chao,Ye, Linglong,Koh, Changwoo,Cai, Yunhao,Wei, Donghui,Woo, Han Young,Sun, Yanming The Royal Society of Chemistry 2018 Journal of Materials Chemistry A Vol.6 No.39
<P>A novel strategy involving judiciously fusing one thiophene/thieno[3,2-<I>b</I>]thiophene on only one side of an indacenodithiophene (IDT) unit to extend IDT backbone conjugation was developed, and three A-D-A type non-fullerene small molecules (TPT-2F, TPTT-2F, and TPTTT-2F) were designed and synthesized to investigate the influence of the extent of IDT core conjugation on their photovoltaic properties. Extending the IDT core conjugation could broaden absorption, upshift the lowest unoccupied molecular orbital (LUMO) energy level, enhance electron mobility, and increase intermolecular π-π stacking. When these three non-fullerene acceptors were applied in organic solar cells (OSCs), simultaneous enhancement of the open-circuit voltage (<I>V</I>oc), short-circuit current (<I>J</I>sc), and fill factor (FF) was obtained, with the degree of enhancement following the order TPT-2F < TPTT-2F < TPTTT-2F. As a result, the TPTTT-2F based OSCs yielded a high PCE of 12.03%. To the best of our knowledge, the PCE of 12.03% is among the highest values for asymmetric non-fullerene acceptor based OSCs so far. These results demonstrate that extending the conjugation of the IDT core is an effective approach to design highly efficient asymmetric non-fullerene acceptors.</P>
Performance Analysis and Power Allocation for NOMA-assisted Cloud Radio Access Network
( Fangcheng Xu ),( Xiangbin Yu ),( Weiye Xu ),( Jiali Cai ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.3
With the assistance of non-orthogonal multiple access (NOMA), the spectrum efficiency and the number of users in cloud radio access network (CRAN) can be greatly improved. In this paper, the system performance of NOMA-assisted CRAN is investigated. Specially, the outage probability (OP) and ergodic sum rate (ESR), are derived for performance evaluation of the system, respectively. Based on this, by minimizing the OP of the system, a suboptimal power allocation (PA) scheme with closed-form PA coefficients is proposed. Numerical simulations validate the accuracy of the theoretical results, where the derived OP has more accuracy than the existing one. Moreover, the developed PA scheme has superior performance over the conventional fixed PA scheme but has smaller performance loss than the optimal PA scheme using the exhaustive search method.