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영양 장애 환자에 대한 지질 영양 수액제 "Trive-1000^(R)"의 효과에 대한 연구
손기섭,배진선,장일성,노승무,박인근,김지연 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2
The association between malnutrition and poor hospital course in surgical patients is well recognized, although it may not involve the causation. When the period of NPO is needed more than several weeks, adequate caloric intake is difficult to maintain, and nutritional status often worsens especially after the operation. Trive-1000^(R) is a ready to use industrial ternary mixture. It fulfills standard requirements for TPN and has a advantage to decrease the cost because of time saving in preparation by the pharmacist and cost saving in disposables(transter sets, bags, filters). It improves safety by less risk of contamination and of error from handling and labelling. A prospective study was undertaken to evaluate the efficacy of Trive-1000^(R) in 34 malnourished patients after the major operation and the results were summarized as follows ; 1) The hemoglobin was not changed and AST, ALT, and bilirubin were increased and BUN and alkaline phosphatase were slightly increased without significance. 2) Mild to moderate toxicities including fever and chill, hepatopathy, thrombophlebitis and hyperglycemia. The infusion was discontinued in one of thrombophlebitis and one of hepatopathy. There results suggest that Trive-1000^(R) is relatively effective and safe TPN agents but requires the large scaled prospective randomized study.
Han, Sang Sub,Kim, Jong Hun,Noh, Chanwoo,Kim, Jung Han,Ji, Eunji,Kwon, Junyoung,Yu, Seung Min,Ko, Tae-Jun,Okogbue, Emmanuel,Oh, Kyu Hwan,Chung, Hee-Suk,Jung, YounJoon,Lee, Gwan-Hyoung,Jung, Yeonwoong American Chemical Society 2019 ACS APPLIED MATERIALS & INTERFACES Vol.11 No.14
<P>Two-dimensional (2D) transition-metal dichalcogenides (2D TMDs) in the form of MX<SUB>2</SUB> (M: transition metal, X: chalcogen) exhibit intrinsically anisotropic layered crystallinity wherein their material properties are determined by constituting M and X elements. 2D platinum diselenide (2D PtSe<SUB>2</SUB>) is a relatively unexplored class of 2D TMDs with noble-metal Pt as M, offering distinct advantages over conventional 2D TMDs such as higher carrier mobility and lower growth temperatures. Despite the projected promise, much of its fundamental structural and electrical properties and their interrelation have not been clarified, and so its full technological potential remains mostly unexplored. In this work, we investigate the structural evolution of large-area chemical vapor deposition (CVD)-grown 2D PtSe<SUB>2</SUB> layers of tailored morphology and clarify its influence on resulting electrical properties. Specifically, we unveil the coupled transition of structural-electrical properties in 2D PtSe<SUB>2</SUB> layers grown at a low temperature (i.e., 400 °C). The layer orientation of 2D PtSe<SUB>2</SUB> grown by the CVD selenization of seed Pt films exhibits horizontal-to-vertical transition with increasing Pt thickness. While vertically aligned 2D PtSe<SUB>2</SUB> layers present metallic transports, field-effect-transistor gate responses were observed with thin horizontally aligned 2D PtSe<SUB>2</SUB> layers prepared with Pt of small thickness. Density functional theory calculation identifies the electronic structures of 2D PtSe<SUB>2</SUB> layers undergoing the transition of horizontal-to-vertical layer orientation, further confirming the presence of this uniquely coupled structural-electrical transition. The advantage of low-temperature growth was further demonstrated by directly growing 2D PtSe<SUB>2</SUB> layers of controlled orientation on polyimide polymeric substrates and fabricating their Kirigami structures, further strengthening the application potential of this material. Discussions on the growth mechanism behind the horizontal-to-vertical 2D layer transition are also presented.</P> [FIG OMISSION]</BR>
Noh, Myoung-Sub,Han, Soo Deok,Chae, Songhwa,Back, Seung Hyuk,Kim, Sangtae,Baek, Seung-Hyub,Kim, Seong Keun,Choi, Ji-Won,Kim, Jin-Sang,Ahn, Dong June,Choi, Dukhyun,Kang, Chong-Yun The Royal Society of Chemistry 2018 Journal of materials chemistry. C, Materials for o Vol.6 No.22
<P>Plasmonic nanocrystals, which exhibit extraordinary optical properties, are challenging to grow in selective positions with a cost-effective and high-throughput process. We demonstrate that plasmonic isotropic gold nanospheres (AuNSs) can be selectively synthesized on wafer-scale rigid and flexible substrates at room temperature by laser irradiation. First, we prepare gold nanocolumn (AuNC) thin films on sapphire and polydimethylsiloxane substrates with glancing angle deposition (GAD). Then, a KrF excimer laser is exposed at selected positions with a 24 ns pulse duration. Finally, highly isotropic AuNSs as plasmonic nanocrystals are synthesized at the targeted positions. We suggest that the formation of such isotropic AuNSs is caused by reshaping from the top of the AuNCs; this is verified by the temperature distribution in the AuNCs during laser irradiation through finite element method simulations. We further investigate the formation of AuNSs by varying the laser energy density and the kind of substrate. By using a simple mask process, we demonstrate patterning of the letters “KIST” <I>via</I> selectively grown AuNSs on a flexible substrate. The simple laser irradiation process on GAD-grown metal NC thin films is expected to be a promising method for scalable synthesis of plasmonic isotropic NSs at targeted positions with a rapid process and at room temperature.</P>
항공기 기반 FMCW-SAR 영상복원을 위한 간소화된 분할연산기법
황지환(Ji-Hwan Hwang),김덕진(Duk-Jin Kim),김진우(Jin-Woo Kim),옥재우(Jae-Woo Ok),신희섭(Hee-Sub Shin),유응노(Eung-Noh You) 한국전자파학회 2017 한국전자파학회논문지 Vol.28 No.9
본 논문에서는 항공기 기반 FMCW-SAR(Frequency Modulated Continuous Wave - Synthetic Aperture Radar) 영상복원을 위해 적용된 기존 back-projection 알고리즘의 계산 효율을 높이고, 연산과정의 복잡도를 단순화시킨 분할연산기법을 제안하며, 이를 적용한 SAR 영상 복원 과정에 대해 설명한다. 제안된 분할연산기법은 상대적으로 좁은 주사폭과 긴 합성개구면을 갖는 항공기 기반 FMCW-SAR 시스템에 효과적으로 적용이 가능하며, back-projection 알고리즘의 영상합성과정에서 분할된 입력 원시자료와 출력 복원영상 간의 상호 기여도가 낮은 자료를 계산 과정에서 생략하여 계산 효율을 높인 연산법이다. 또한, 실제 항공기 기반 FMCW-SAR 원시자료 복원과정에 적용하여 계산 효율의 개선 정도를 비교분석하였다. Simplified factorizing-technique to improve the efficiency on computational procedure and the complexity of the conventional backprojection algorithm, which is used to reconstruct airborne FMCW-SAR image, is suggested, and the reconstruction process of SAR image by this simplified factorizing-technique are presented in this paper. This technique can be efficiently applied to airborne FMCWSAR having a relatively narrow beamwidth and long synthetic aperture length, and its basic rationale is to exclude the data that has low level of contribution during computational procedure. Using the raw data of practical airborne FMCW-SAR system, performances of this proposed technique such as SAR image quality and processing time were compared and analyzed.
이충섭 ( Chung-sub Lee ),김지언 ( Ji-eon Kim ),노시형 ( Si-hyeong Noh ),김태훈 ( Tae-hoon Kim ),이윤오 ( Yun Oh Lee ),유영주 ( Yeong-ju Yu ),천정범 ( Jungbum Chun ),정창원 ( Chang-won Jeong ) 한국정보처리학회 2020 한국정보처리학회 학술대회논문집 Vol.27 No.2
최근 의료데이터의 표준화를 기반으로 다양한 임상연구가 국내외에서 활발하게 진행되고 있다. 그러나 대부분 개발기술이 임상현장에 적용되지 못하는 이유는 상이한 인프라로 인한 일관성있는 결가를 도출하지 못하는 문제점과 부족한 진단지표와 기준 그리고 충분하지 못한 기술적·임상적 검증이 문제가 되고 있다. 본 논문에서는 이러한 문제점을 해결하기위한 새로운 통합 플랫폼을 제안하고자 한다. 이를 위해서 임상데이터는 OHDSI의 OMOP-CDM으로 표준화되어야 하며, 이외에 의료영상 정보를 포함한다. 제안한 플랫폼은 표준화된 데이터를 통해 지속적인 자가 학습을 수행하며, 질환별 진단에 필요한 개발 도구와 분석 소프트웨어 도구를 통해 다양한 타겟 질환연구를 지원한다. 제안한 플랫폼은 질환에 대한 비침습적 진단을 위해 의료영상을 기반으로 데이터표준화을 기반으로하며, 이를통해 인공지능 기술을 개발하고 병원 정보시스템과 연계하여 임상현장에 실증을 통해 검증하고자 한다.