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Ku, Jeonghun,Lee, Jang Han,Han, Kiwan,Kim, Sun I.,Kang, Youn Joo,Park, Eun Sook Wolters Kluwer Health, Inc. All rights reserved. 2009 AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITA Vol.88 No.9
Ku J, Lee JH, Han K, Kim SI, Kang YJ, Park ES: Validity and reliability of cognitive assessment using virtual environment technology in patients with stroke. OBJECTIVES:: We assessed the validity and reliability of a virtual environment technology (VET)-based cognitive assessment program that was developed as a measurement tool of cognitive abilities in patients after a stroke. DESIGN:: Twenty participants diagnosed with stroke caused by unilateral brain lesions were enrolled to assess the VET program’s validity and test-retest reliability. Participants underwent evaluation by paper-based neuropsychological tests including the Korean Mini-Mental Status Examination, the Korean-Wechsler Adult Intelligence Scale, the Motor Free Visual Perception Test, Rey-Kim Memory Test, and Kim’s Frontal-Executive Neuropsychologic Test as well as the VET-based cognitive assessment. Major variables and indices of the VET program were calculated. The VET program validity was evaluated using a simple correlation analysis between variables from the VET program and conventional paper-based neuropsychological measurements, and the reliability was evaluated by investigating the test-retest correlation coefficients. RESULTS:: Major variables and indices of the VET program in patients with stroke correlated significantly with the related scores of paper-based neuropsychological tests. In addition, the test-retest reliability analysis revealed that the correlation coefficients ranged from 0.528 to 0.926. CONCLUSION:: The VET-based cognitive assessment program showed adequate reliability and validity as a method of cognitive assessment in patients after stroke.
Kim, Jeonghun,Koh, Jong Kwan,Kim, Byeonggwan,Ahn, Sung Hoon,Ahn, Hyungju,Ryu, Du Yeol,Kim, Jong Hak,Kim, Eunkyoung WILEY‐VCH Verlag 2011 Advanced Functional Materials Vol.21 No.24
<P>An iodine‐free solid‐state dye‐sensitized solar cell (ssDSSC) with 6.8% efficiency can be fabricated using conductive polymers and organized mesoporous TiO<SUB>2</SUB>. On page 4633, Eunkyoung Kim, Jong Hak Kim, and co‐workers show the effects of polymer conductivity and transmittance of the interfacial TiO<SUB>2</SUB> layer on energy conversion efficiency. This method can be used for the fabrication of various photovoltaic cells. </P>
Kim, Byeonggwan,Koh, Jong Kwan,Kim, Jeonghun,Chi, Won Seok,Kim, Jong Hak,Kim, Eunkyoung Wiley-VCH 2012 CHEM SUS CHEM Vol.5 No.11
<P>A solid-state polymerizable monomer, 2,5-dibromo-3,4-propylenedioxythiophene (DBProDOT), was synthesized at 25?C to produce a conducting polymer, poly(3,4-propylenedioxythiophene) (PProDOT). Crystallographic studies revealed a short interplane distance between DBProDOT molecules, which was responsible for polymerization at low temperature with a lower activation energy and higher exothermic reaction than 2,5-dibromo-3,4-ethylenedioxythiophene (DBEDOT) or its derivatives. Upon solid-state polymerization (SSP) of DBProDOT at 25?C, PProDOT was obtained in a self-doped state with tribromide ions and an electrical conductivity of 0.05?S?cm?1, which is considerably higher than that of chemically-polymerized PProDOT (210?? S?cm?1). Solid-state 13C?NMR spectroscopy and DFT calculations revealed polarons in PProDOT and a strong perturbation of carbon nuclei in thiophenes as a result of paramagnetic broadening. DBProDOT molecules deeply penetrated and polymerized to fill nanocrystalline TiO2 pores with PProDOT, which functioned as a hole-transporting material (HTM) for I2-free solid-state dye-sensitized solar cells (ssDSSCs). With the introduction of an organized mesoporous TiO2 (OM-TiO2) layer, the energy conversion efficiency reached 3.5?% at 100?mW?cm?2, which was quite stable up to at least 1500?h. The cell performance and stability was attributed to the high stability of PProDOT, with the high conductivity and improved interfacial contact of the electrode/HTM resulting in reduced interfacial resistance and enhanced electron lifetime.</P>
Effect of berberine on p53 expression by TPA in breast cancer cells.
Kim, Sangmin,Han, Jeonghun,Kim, Nam-Young,Lee, Se Kyung,Cho, Dong Hui,Choi, Min-Young,Kim, Jee Soo,Kim, Jung-Han,Choe, Jun-Ho,Nam, Seok Jin,Lee, Jeong Eon National Hellenic Research Foundation 2012 Oncology reports Vol.27 No.1
<P>Berberine (BBR), an isoquinoline derivative alkaloid compound, has been reported to have anti-oxidant and anti-carcinogenic effects. A loss of functional p53 is involved with an increased risk of cancer proliferation and metastasis. Here, we investigated the effect of BBR on the transcriptional activity and the protein expression of p53 in p53-positive (wild- type, MCF7 cells) and p53-negative (mutant, MDA-MB231 cells) human breast cancer cells. Our results showed that the basal level of p53 mRNA and protein expression was increased by BBR treatment. However, tumor promoter, TPA, decreased the level of p53 mRNA and protein expression in MCF7 cells with wild-type p53. In addition, TPA-induced down-regulation of p53 mRNA and protein expression was increased by UO126, but not by SP600125 and SB203580. To verify the regulatory mechanism of p53 protein expression, we investigated the effects of proteasomal inhibitors (ALLN and MG132) or a lysosomal inhibitor (chloroquine) on TPA-induced down-regulation of p53. We observed that TPA-induced down-regulation of p53 protein was prevented by ALLN and MG132, but not by chloroquine. Further, we investigated the effect of BBR on TPA-induced down-regulation of p53 mRNA and protein levels. Interestingly, the levels of TPA-induced down-regulation of p53 mRNA and protein were prevented by BBR, but MDA-MB231 cells with mutated p53 were not affected. In addition, TPA-induced down-regulation of p53 mRNA was also prevented by BBR. Taken together, we suggest that BBR may be used as an effective ingredient for anticancer products, which trigger the transcriptional activity and the inhibition of the degradation of p53, a tumor suppressor gene, in human breast cancer.</P>
VR-Based Conversation Training Program for Patients with Schizophrenia: A Preliminary Clinical Trial
Ku, Jeonghun,Han, Kiwan,Lee, Hyung Rae,Jang, Hee Jeong,Kim, Kwang Uk,Park, Sung Hyouk,Kim, Jae Jin,Kim, Chan Hyung,Kim, In Young,Kim, Sun I. Mary Ann Liebert 2007 Cyber Psychology & Behavior Vol.10 No.4
일제강점기 재만 조선인 이주문학 연구 - 이주·정착과정의 시적 형상화를 중심으로 -
김정훈(Kim Jeonghun),정덕준(Chung Dukjoon) 한국언어문학회 2006 한국언어문학 Vol.56 No.-
Until now research mostly treated Chinese-Korean Literature on Manchuria as a literature in exile. This way don’t reflect actuality of Manchuria under the Japanese Colonial Period. Because, in this paper I divided the Chinese-Korean Poetry under the Japanese Colonial Period into several classes with the viewpoint which is a encapsulated the history of their emigration and domiciliation. First of all, it starts with a literature in exile before 1920s. The most works are foregrounding an anti-Japanese combative consciousness and the hope to a national right recovery. Kim Tack-young and Shin Jung and Shin Chae-ho are typical writer of this age. Even in after, literature that reject the foreign power like this placed a important quality of it. The Chinese-Korean poetry until 1920s is not an particular different point from with interior poems as such poets in charge or to selected form. Only, in contents, it frequently appears strongly foregrounds anti-Japanese combative consciousness of interior literature. The poems after 1930s is individually show racial consciousness of different kind from poems of KAPF or nationalism at home. This is natural that the Manchuria when is because is a base of anti-Japanese independence movement. It was started from 1930s that makes exile’s life as emigrant to Manchuria with subject matter of the Chinese-Korean Poetry. This time when that it is a widely and systematic range executed plan as emigration a national policy. It becomes literary encapsulated with the features which is various aspect with vague expectation and hope about Manchuria, homesick, maladjustment in alien and deploring actuality trouble. An aspect of emigrated Korean to endured any kind of trials appears in diverse works on Manchuria. The Chinese-Korean literature in domiciliate step on Manchuria described settlement' conflict with Chinese landowner and their poverty and suffering because of the Japanese colony rule in China likewise in their homeland. The representative writers are Kim Jo-kyu, Lee Uk, etc. The poems from 1930 to 1940’s described various lives of settlers : an anti-Japanese struggle, a will of settle, and escapism. The representative writers are Song Chul-ly, Chun Chun-song, Shim Yeon-su and so on. It grasps the Chinese-Korean poetry under the Japanese Colonial Period when point of view with not a literature in exile but literature of the emigration and domiciliation. Many poets who had various works in this time was not referred almost from the history of literature on and after the middle of 1930s. Reasonable research of its works is urgent for just corroboration of Korean Poetry. Their works are plentifully putting in the features of immigration and fixation. There is a necessity which will judge their poetry straightly. The poetry of the glorious restoration is most rapture of regain of country and ovation of land reform. This works becomes the strong and steady base of the Chinese-Korean Poetry.