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      • 전력시스템의 부하주파수 제어를 위한 IA-PID 제어기 특성에 관한 연구

        정형환,김창현,이정필,정문규 동아대학교 정보기술연구소 2001 情報通信硏究所論文誌 Vol.9 No.1

        In this paper, the robust PID controller using immune algorithm(IA) for load frequency control(LFC) is designed. In proposed method, objective function is represented as antigens. An affinity calculation is embedded within the algorithm for determining the promotion or suppression of antibody. Simulation results show that the proposed robust load frequency controller can achieve good performance even in the presence of generation rate constraints

      • 선천성 대사 이상 환아에서 발생한 대사 위기의 복막 투석 치료 효과

        강정혜,이동환,문철,김은미 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

        Purpose : We have evaluated the outcomes of peritoneal dialysis in patients with metabolic crises caused by in born error of metabolism. Methods : There are 6 patients(8 episodes, 4 males and 2 females) who had inherited inborn errors of metabolism and were admitted to the department of pediatrics, Shoonchunhyang university hospital in Seoul from December 1991 to December 1994. The technique of dialysis is discribed, in short: A Tenckhoff catheter was inserted surgically in all patients through the lateral abdominal wall. Commerically available dialysate solutions(Peritosol, Korea Green Cross Co.) was applied to 5 patients(7 cases) with hyperammonemia. In a patient with propionic acidemia, we used a special custiom made dialysate that replaces lactate by bicarbonate. Results : 1) The mean age was 5.3 months old. There were 6 patients with 8 episodes. Six cases had Ornithin transcarbamylase deficiency. The remaining cases are Multiple carboxylase deficiency and Propionic acidemia (Table 1) 2) In 7 cases with hyperammonemia, mean levels of pre and post 24hrs peritoneal dialysis serum ammonia were 1000.2±310.9 ㎍/dl and 388.8 ±156.7 ㎍/dl at 24 hours respectively. Time on serum ammonia levels reached below 300 ㎍/dl was 88.7 ±39.6 ㎍/dl hours. 3) Four out of seven cases were a recorvert of mental status. Each episode of serum ammonia mean levels was 388.8 ±156.7 ㎍/dl after 19.7 ±5.8 hours of peritoneal dialysis (Table 3). 4) Peak serum ammonia levels of the survived group reached 1356.5 ㎍/dl, higher than the expired group of 847.5 ㎍/dl and time period of starting peritoneal dialysis after onset of the survived group was 15.5 hours earlier than the expired group of 23 hours(P>0.05)(Table 4). 5) 3 out of 7 cases of hyperammonemia died. The cause if death were 3 brain edema, 1 hyperkalemla and 1 intracranlal hemorrhage. 6) In onecase with Multiple carboxylase deficiency, serum ammonia level was normalized after 12 hours of peritoneal dialysis. The reduction of serum levels of the branched amino acid was also observed. 7) In a case of Propionic acidemia with severe metabolic acidosis, the prior serum bicarbonate level was 8 mmol/L and was increased up to 18 mmol/L by peritoneal dialysis lasting 19 hours. 8) Among 8 cases, complications of peritoneal dialysis were 5 hypoalbuminemia, 4 hyoercalcemia, 4 hyperglycemia and leakage of peritoneal dialysate. Conclusions : In cases of hyperammonemia, survival rate is 57.1%. They are showed excellant efficacy of treatment of peritoneal dialysis for metabolic crises. In a case of propinic acidemia is fastly corrected by peritoneal dialysis. But unfortunally clinical manifestations is not improved. Therefore, further studies is required with treatment of severe metabolic acidic conditions.

      • 회수수 안정화제를 사용한 콘크리트의 공학적 특성에 관한 연구

        김기정,金光華,이문환,이세현,한천구 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

        In this study is investigated the engineering properties of concrete using stabilizing agent of recycling water in order to suggest a practical use of recycling water. According to the results. as stabilizing agent is added. fluidity and air content varies slightly with W/C, but does not make a big difference. Bleeding is reduced by adding stabilizing agent, and so it decreases by about 40% at the adding ratio of 0.15%. When stabilizing agent is not added, compressive strength decreases in comparison with plain concrete, but increases by adding stabilizing agent, so it is largest at adding ratio of 0.30%(W/C 30%) and 0.15%(W/C 40, 50%). Length change by drying shrinkage is larger than plain concrete in the case of no adding of stabilizing agent, but decreases by the use of stabilizing agent. Therefore, it is thought that when stabilizing agent is added to recycling water, quality deterioration of concrete is prevented, moreover, quality of concrete can be improved.

      • 안정화제를 사용한 회수수의 고형분량 및 방치시간에 따른 시멘트 모르터의 특성

        金光華,김기정,이문환,이세현,한천구 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

        This study is intended to investigate the fundamental properties of cement mortar with solid content and leaving time of recycled water that stabilizing agent is added. According to the results, fluidity and air content does not make a big difference with variation of solid content. As the leaving time of recycled water is long, fluidity and air content increases. Setting time is shortened due to fine particle with an increase of solid content and leaving time. Compressive strength and flexural strength increase with an increase of solid content, and they increase at the leaving time of 1 day, but decrease after 2days. Length change by drying shrinkage is smaller than that of plain concrete, and is almost same with variation of solid content. And it is reduced at the leaving time of 1 day, but increases after that. Therefore, it analyzed that the effect of stabilizing agent is best under condition of adding ratio of 0.15%, solid content of 3% and leaving time of 1day, and it also works upto solid content of 5% and leaving time of 2days.

      • KCI등재

        낭종 적출후 악골 결손부 치유에 관한 동종골 이식 효과에 관한 연구

        이동근,박화규,권경환,강문정,신기영,민승기,성헌모 大韓顎顔面成形再建外科學會 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.4

        This study was aimed to suggest to better treatment method of jaw cyst that the maximum diameter was wider than 3cm, using different treatment and clinical and radiographic result. We divided the 60 patients into three groups, group A(20 patients) were treated with cyst enucleation and Decalcified Freeze-Dried Allogeneic Bone(DFDB) graft, group B(20 patients) were treated with cyst enucleation and autogenous bone graft, group C(20 patients) were treated with only cyst enucleation. Each group was evaluated with panramic radiograph and clinical sign & symptom at pre-op and post-op(immediate, 6, 12, 24, 36 month). Bone density was evaluated with disital densitometer. The result was as follows : 1. Post-Op infection was higher in group C(4 pts.) than in group A(1 pt.) and B(1 pt.) 2. Post-Op gingival recession was higher in group C(3 Pts.) than in group A(1 pt.) and B(1 pt.) 3. Anatomic distortion was higher in group C(3 Pt.) than in group A(1 Pt.), and B(1 pt.) 4. reoperation was done in two patients who were in group C 5. There were donor site morbidity in two patients 6. there was no significant difference between group A and B in their bony density in their follow up period(p>0.05). 7. There were significant differences between group A, B and group C in their bony density until post-op 24 months but a little differences at post-op 36 months(P<0.01)

      • SCISCIESCOPUS
      • Auxin response factor gene family in <i>Brassica rapa</i> : genomic organization, divergence, expression, and evolution

        Mun, Jeong-Hwan,Yu, Hee-Ju,Shin, Ja Young,Oh, Mijin,Hwang, Hyun-Ju,Chung, Hee Springer-Verlag 2012 Molecular genetics and genomics Vol.287 No.10

        <P>Completion of the sequencing of the <I>Brassica rapa</I> genome enabled us to undertake a genome-wide identification and functional study of the gene families related to the morphological diversity and agronomic traits of <I>Brassica</I> crops. In this study, we identified the auxin response factor (<I>ARF</I>) gene family, which is one of the key regulators of auxin-mediated plant growth and development in the <I>B. rapa</I> genome. A total of 31 <I>ARF</I> genes were identified in the genome. Phylogenetic and evolutionary analyses suggest that <I>ARF</I> genes fell into four major classes and were amplified in the <I>B. rapa</I> genome as a result of a recent whole genome triplication after speciation from <I>Arabidopsis thaliana</I>. Despite its recent hexaploid ancestry, <I>B. rapa</I> includes a relatively small number of <I>ARF</I> genes compared with the 23 members in <I>A. thaliana</I>, presumably due to a paralog reduction related to repetitive sequence insertion into promoter and non-coding transcribed region of the genes. Comparative genomic and mRNA sequencing analyses demonstrated that 27 of the 31 <I>BrARF</I> genes were transcriptionally active, and their expression was affected by either auxin treatment or floral development stage, although 4 genes were inactive, suggesting that the generation and pseudogenization of <I>ARF</I> members are likely to be an ongoing process. This study will provide a fundamental basis for the modification and evolution of the gene family after a polyploidy event, as well as a functional study of <I>ARF</I> genes in a polyploidy crop species.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1007/s00438-012-0718-4) contains supplementary material, which is available to authorized users.</P>

      • Genome-wide identification of NBS-encoding resistance genes in <i>Brassica rapa</i>

        Mun, Jeong-Hwan,Yu, Hee-Ju,Park, Soomin,Park, Beom-Seok Springer-Verlag 2009 Molecular genetics and genomics Vol.282 No.6

        <P>Nucleotide-binding site (NBS)-encoding resistance genes are key plant disease-resistance genes and are abundant in plant genomes, comprising up to 2% of all genes. The availability of genome sequences from several plant models enables the identification and cloning of NBS-encoding genes from closely related species based on a comparative genomics approach. In this study, we used the genome sequence of <I>Brassica rapa</I> to identify NBS-encoding genes in the <I>Brassica</I> genome. We identified 92 non-redundant NBS-encoding genes [30 CC-NBS-LRR (CNL) and 62 TIR-NBS-LRR (TNL) genes] in approximately 100 Mbp of <I>B. rapa</I> euchromatic genome sequence. Despite the fact that <I>B. rapa</I> has a significantly larger genome than <I>Arabidopsis thaliana</I> due to a recent whole genome triplication event after speciation, <I>B. rapa</I> contains relatively small number of NBS-encoding genes compared to <I>A. thaliana</I>, presumably because of deletion of redundant genes related to genome diploidization. Phylogenetic and evolutionary analyses suggest that relatively higher relaxation of selective constraints on the TNL group after the old duplication event resulted in greater accumulation of TNLs than CNLs in both <I>Arabidopsis</I> and <I>Brassica</I> genomes. Recent tandem duplication and ectopic deletion are likely to have played a role in the generation of novel <I>Brassica</I> lineage-specific resistance genes.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1007/s00438-009-0492-0) contains supplementary material, which is available to authorized users.</P>

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