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박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2
최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.
Protective Effect of Oak Extracts on Oxidative Stress Induced by Hydrogen Peroxide
Jeong Bin Nam,Hyung Bin Park,Ji Young Jung,Jae Kyung Yang 한국목재공학회 2014 목재공학 Vol.42 No.5
This study was done to evaluate the antioxidant effect of oak hot water extracts on the oxidative stress induced byreactive oxygen species (ROS). The cytotoxicity of H2O2-induced oxidative stress was performed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay for the cell viability according to the dose-dependenttreatment. Oak extracts demonstrated a dose-dependent ability to inhibit H2O2-induced apoptosis in cultured tenofibroblasts,as assessed by MTT assay and FACS analysis. H2O2 increased the phosphorylation of extracellular regulatedkinase1/2 (ERK1/2) and of c-Jun N-terminal kinase (JNK) and the production of reactive oxygen species (ROS). Incontrast, treatment with oak extracts was decreased this activation of ERK1/2 and JNK, as confirmed by western blotanalysis, and reduced the production of ROS, as verified by fluorescent microscopic and flow cytometry (FACS)analyses. These findings suggest that oak extracts, by suppressing JNK, ERK1/2, and intracellular ROS production,have a concentration-dependent antiapoptotic effect on achilles tenofibroblasts exposed to an oxidative stressor, andmay have therapeutic potential.
Coagulation Treatment of Wastewater Using Torrefied Wood Powder
Jeong Bin Nam,Seung Min Yang,Geun Hye Oh,Seog-Goo Kang 한국펄프·종이공학회 2018 펄프.종이技術 Vol.50 No.6
Water quality pollution is becoming a serious social problem due to the improvement of living standards due to economic and population growth in cities. Many researches have been carried out for the efficient treatment of municipal sewage and new research is underway. In particular, as the demand for products used in physico-chemical treatment increases, the research for the development of a more safe and efficient water treatment agent is needed. This study investigated the coagulation characteristics of superfine steamed torrefied wood powder for application to domestic sewage and investigated the possibility of its use as a better coagulant or flocculant than the existing ones. Since torrefied wood flour is an eco-friendly material that is harmless to the environment, it can be used more safely than the conventional flocculants and will help improve treatment efficiency in the water treatment process as a flocculant or a coagulant. The aim of this study was to investigate nutrient reduction using torrefied wood powder (TWP) as a flocculant for wastewater treatment. The TWP flocculant were successfully removed over 96% of the turbidity. COD in the wastewater at the following optimal TWP dosage: 10% for COD and TP. Therefore, TWP can be a promising flocculants due to its high efficiency and low dose requirements. In addition, TWPs including C-PAM do not contaminate treated wastewater, which can be recycled to reduce not only the cost and the demand for treated water, but also the extra operational costs for fresh reusing wastewater.
< 전시-P-90 >Antioxidative Effect of Extracts According to torrefied Condition
( Jeong Bin Nam ),( Geun Hye Oh ),( Seung Min Yang ),( Seog-goo Kang ) 한국목재공학회 2018 한국목재공학회 학술발표논문집 Vol.2018 No.1
Torrefaction is one of the woody biomass thermal pretreatment methods which has been studied to improve the loss of raw materials from carbonization and to evaluate characteristics of torrified products according to temperature and reaction time. The heat-treated torrefied wood has increased the phenol content, phenoxy radical concentration, and antioxidant activities due to the previous studies. The increasing are being known due to the ability of hydrogen donation of the phenol function and the torrefiying wood antioxidant function for the lignin and wood extraction. On the other hand, the superheated steam treatment is a heat treatment method which is being studied to improve the added value of wood forming terrified powder with high temperature steam of 300C or more by using superheated steam treatment apparatus. In this study, the antioxidative and antioxidant activities of extract torrefied wood were investigated in order to examine the antioxidant - containing wood carbides. As a result, the antioxidant effect of extraction of torrefied wood which made by super heated steam treatment was increased in concentration - dependent manner, and the concentration of 300℃ was higher than 350℃ in 10 minutes.
Evaluation of Antioxidant Activities of Water Extract from Microwave Torrefied Oak Wood
( Jeong Bin Nam ),( Geun Hye Oh ),( Seung Min Yang ),( Seok-eon Lee ),( Seog-goo Kang ) 한국목재공학회 2018 목재공학 Vol.46 No.2
The aim of this study was to assess the in vitro potential of water extract from torrefied oak wood as a natural antioxidant. The antioxidant potential of the extracts was assessed by employing different in vitro assays, including reducing power, DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS [2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)], and FRAP (ferric reducing antioxidant potential) assays. The DPPH activity of the extract was increased in a dosedependent manner. Measurement of total flavonoid content of water extract from torrefied oak wood was achieved using an aluminum chloride colorimetric assay; the extract contained 192.12 mg/g flavonoid, which was significantly high when compared with standard quercetin. The results obtained in this study indicate that water extract from torrefied oak wood has significant potential for use as a natural antioxidant agent.
Kwon, Jeong Hyun,Park, Junhong,Lee, Myung Keun,Park, Jeong Woo,Jeon, Yongmin,Shin, Jeong Bin,Nam, Minwoo,Kim, Choong-Ki,Choi, Yang-Kyu,Choi, Kyung Cheol American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.18
<P>The lack of reliable, transparent, and flexible electrodes and insulators for applications in thin-film transistors (TFTs) makes it difficult to commercialize transparent, flexible TFTs (TF-TFTs). More specifically, conventional high process temperatures and the brittleness of these elements have been hurdles in developing flexible substrates vulnerable to heat. Here, we propose electrode and insulator fabrication techniques considering process temperature, transmittance, flexibility, and environmental stability. A transparent and flexible indium tin oxide (ITO)/Ag/ITO (IAI) electrode and an Al<SUB>2</SUB>O<SUB>3</SUB>/MgO (AM)-laminated insulator were optimized at the low temperature of 70 °C for the fabrication of TF-TFTs on a polyethylene terephthalate (PET) substrate. The optimized IAI electrode with a sheet resistance of 7 Ω/sq exhibited the luminous transmittance of 85.17% and maintained its electrical conductivity after exposure to damp heat conditions because of an environmentally stable ITO capping layer. In addition, the electrical conductivity of IAI was maintained after 10 000 bending cycles with a tensile strain of 3% because of the ductile Ag film. In the metal/insulator/metal structure, the insulating and mechanical properties of the optimized AM-laminated film deposited at 70 °C were significantly improved because of the highly dense nanolaminate system, compared to those of the Al<SUB>2</SUB>O<SUB>3</SUB> film deposited at 70 °C. In addition, the amorphous indium-gallium-zinc oxide (a-IGZO) was used as the active channel for TF-TFTs because of its excellent chemical stability. In the environmental stability test, the ITO, a-IGZO, and AM-laminated films showed the excellent environmental stability. Therefore, our IGZO-based TFT with IAI electrodes and the 70 °C AM-laminated insulator was fabricated to evaluate robustness, transparency, flexibility, and process temperature, resulting in transfer characteristics comparable to those of an IGZO-based TFT with a 150 °C Al<SUB>2</SUB>O<SUB>3</SUB> insulator.</P> [FIG OMISSION]</BR>