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RISS 인기검색어
- 검색키워드
- 저자 : Javad Tavakoli (검색결과 3 건)
- 무료
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Tissue Engineering of the Intervertebral Disc’s Annulus Fibrosus: A Scaff old-Based Review Study
Javad Tavakoli 한국조직공학과 재생의학회 2017 조직공학과 재생의학 Vol.14 No.2
Tissue engineering as a high technology solution for treating disc’s problem has been the focus of some researches recently; however, the upcoming successful results in this area depends on understanding the complexities of biology and engineering interface. Whereas the major responsibility of the nucleus pulposus is to provide a sustainable hydrated environment within the disc, the function of the annulus fibrosus (AF) is more mechanical, facilitating joint mobility and preventing radial bulging by confining of the central part, which makes the AF reconstruction important. Although the body of knowledge regarding the AF tissue engineering has grown rapidly, the opportunities to improve current understanding of how artificial scaffolds are able to mimic the AF concentric structure—including inter-lamellar matrix and cross-bridges—addressed unresolved research questions. The aim of this literature review was to collect and discuss, from the international scientific literature, information about tissue engineering of the AF based on scaffold fabrication and material properties, useful for developing new strategies in disc tissue engineering. The key parameter of this research was understanding if role of cross-bridges and inter-lamellar matrix has been considered on tissue engineering of the AF.
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Javad Tavakoli,Mohammad E. Khosroshahi 대한의용생체공학회 2018 Biomedical Engineering Letters (BMEL) Vol.8 No.3
The surface properties of implant are responsible to provide mechanical stability by creating an intimate bond between thebone and implant; hence, play a major role on osseointegration process. The current study was aimed to measure surfacecharacteristics of titanium modified by a pulsed Nd:YAG laser. The results of this study revealed an optimum density oflaser energy (140 Jcm-2), at which improvement of osteointegration process was seen. Significant differences were foundbetween arithmetical mean height (Ra), root mean square deviation (Rq) and texture orientation, all were lower for140 Jcm-2 samples compared to untreated one. Also it was identified that the surface segments were more uniformlydistributed with a more Gaussian distribution for treated samples at 140 Jcm-2. The distribution of texture orientation athigh laser density (250 and 300 Jcm-2) were approximately similar to untreated sample. The skewness index that indicateshow peaks and valleys are distributed throughout the surface showed a positive value for laser treated samples, compared tountreated one. The surface characterization revealed that Kurtosis index, which tells us how high or flat the surface profileis, for treated sample at 140 Jcm-2 was marginally close to 3 indicating flat peaks and valleys in the surface profile.
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Luca Ambrosio,Gianluca Vadalà,Javad Tavakoli,Laura Scaramuzzo,Giovanni Barbanti Brodano,Stephen J. Lewis,So Kato,Samuel K. Cho,S. Tim Yoon,김호중,Matthew F. Gary,Vincenzo Denaro 대한척추신경외과학회 2024 Neurospine Vol.21 No.1
Objective: To evaluate the global practice pattern of wound dressing use after lumbar fusion for degenerative conditions. Methods: A survey issued by AO Spine Knowledge Forums Deformity and Degenerative was sent out to AO Spine members. The type of postoperative dressing employed, timing of initial dressing removal, and type of subsequent dressing applied were investigated. Differences in the type of surgery and regional distribution of surgeons’ preferences were analyzed. Results: Right following surgery, 60.6% utilized a dry dressing, 23.2% a plastic occlusive dressing, 5.7% glue, 6% a combination of glue and polyester mesh, 2.6% a wound vacuum, and 1.2% other dressings. The initial dressing was removed on postoperative day 1 (11.6%), 2 (39.2%), 3 (20.3%), 4 (1.7%), 5 (4.3%), 6 (0.4%), 7 or later (12.5%), or depending on drain removal (9.9%). Following initial dressing removal, 75.9% applied a dry dressing, 17.7% a plastic occlusive dressing, and 1.3% glue, while 12.1% used no dressing. The use of no additional coverage after initial dressing removal was significantly associated with a later dressing change (p < 0.001). Significant differences emerged after comparing dressing management among different AO Spine regions (p < 0.001). Conclusion: Most spine surgeons utilized a dry or plastic occlusive dressing initially applied after surgery. The first dressing was more frequently changed during the first 3 postoperative days and replaced with the same type of dressing. While dressing policies tended not to vary according to the type of surgery, regional differences suggest that actual practice may be based on personal experience rather than available evidence.
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