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RISS 인기검색어
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- 저자 : Imen Hammami (검색결과 4 건)
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Effects of Garlic Fractions Consumption on Male Reproductive Functions
Imen Hammami,Afef Nahdi,Fatma Atig,Wided Kouidhi,Mohamed Amri,Mehrzia Mokni,Ahmed El May,Miche`le El May 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.1
Many researchers have focused on the preventive and curative effects of garlic (Allium sativum), particularly on cardiovascular diseases and cancer. However, its impacts on the male reproductive system have not been clearly defined. In this study, the effect of chronic consumption of two garlic fractions was tested: one soluble in water (aqueous solution obtained by grinding and centrifugation) and the other one precipitated by ethanol (alcoholic precipitate obtained by precipitation of the aqueous solution), on different variables of male rats’ reproductive functions. These two fractions were targeted to try to identify the nature of the active garlic compounds responsible for the different modifications observed on testicular parameters. The observation of seminiferous tubules of rats treated with garlic fractions showed an increased number of tubules deprived of spermatozoa. In addition, garlic fractions induced apoptosis of testicular germ cells (TdTmediated dUTP-X nick-end labeling [TUNEL] approach) and a decrease of serum testosterone levels and seminiferous tubule DNA concentrations. In summary, our histological and molecular results suggest that one or several substances, soluble in water and precipitated by alcohol, impaired spermatogenesis.
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HLPSP: A Hybrid Live P2P Streaming Protocol
( Chourouk Hammami ),( Imen Jemili ),( Achraf Gazdar ),( Abdelfettah Belghith ),( Mohamed Mosbah ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.3
The efficiency of live Peer-to-Peer (P2P) streaming protocols depends on the appropriateness and the management abilities of their underlying overlay multicast. While a tree overlay structure confines transmission delays efficiently by maintaining deterministic delivery paths, an overlay mesh structure provides adequate resiliency to peers dynamics and easy maintenance. On the other hand, content freshness, playback fluidity and streaming continuity are still challenging issues that require viable solutions. In this paper, we propose a Hybrid Live P2P Streaming Protocol (HLPSP) based on a hybrid overlay multicast that integrates the efficiency of both the tree and mesh structures. Extensive simulations using OMNET++ are conducted to investigate the efficiency of HLPSP in terms of relevant performance metrics, and position HLPSP with respect to DenaCast the enhanced version of the well-known CoolStreaming protocol. Simulation results show that HLPSP outperforms DenaCast in terms of startup delay, end-to-end delay, play-back delay and data loss.
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Dhekra Grami,Kaıs Rtibi,Imen Hammami,Slimen Selmi,Luca De Toni,Carlo Foresta,Lamjed Marzouki,Hichem Sebai 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.6
Eruca sativa action on the male reproductive system and fertility has not been precisely defined. In this study, the aim was to investigate the ameliorative activity of E. sativa aqueous extracts (ESAE) on reproductive toxicity associated with oxidative stress induced by bisphenol A (BPA). Wistar rats were used and divided into six groups of animals each; control (0.4 mL of corn oil/rat), ESAE at the higher dose (200 mg/kg), BPA [100 mg/kg, body weight (b.w.), perorally (p.o.)] alone, or in combination with varied doses of ESAE (50, 100, and 200 mg/kg, b.w, p.o.). The diverse doses were administrated orally for 30 consecutive days. The results showed that BPA-treatment produced a diminution of density, motility, and viability of sperm with disruption of spermatozoa morphology and fertilizing potential as well as testosterone, luteinizing hormone, and follicle stimulating hormone levels. These results were accompanied by testis and epididymis histological damages, which were shown by an induction of testicular dysfunction as seen with a lower number of Leydig-cells and spermatocytes as well as a reproductive stress which was modeled. The oxidative stress was measured by malondialdehyde production, thiol group (-SH) decline and antioxidant enzyme activities disturbance, in particular superoxide dismutase, catalase, and glutathione peroxidase in reproductive tissues. ESAE coadministration at the two lower doses improved all histological and biochemical parameter injuries. These finding suggested the ESAE ability to prevent the testicular damages in rats, which might be linked to functional-bioactive substances such as phenolic compounds with higher antioxidant capacity.
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Fatma Arrari,Mohamed-Amine Jabri,Imen Hammami,Hichem Sebai 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.9
Pectin is a polysaccharide attached to carbohydrates. These are substances exclusively of plant origin. The aim of the present study is to evaluate the laxative effects of orange peel pectin extract (OPPE) against constipation induced by loperamide (LOP) in rats. Rats were equally divided into six groups and treated daily 1 week as follows: Control, LOP (3 mg/kg, body weight [b.w.], Per Os [p.o.]), LOP+yohimbine (2 mg/kg, b.w., i.p.), and LOP+OPPE (6.25, 12.5, and 25 mg/kg, b.w., p.o.). At the end of the experiment, the effects of OPPE were assessed by fecal parameters (numbers, weight, and water content), gastrointestinal transit, gastric emptying, serum metabolic parameter changes, intestinal and colon mucosa oxidative stress, and the histological examination. The defecation test showed that administration of LOP (3 mg/kg, b.w., p.o.) leads to the production of remarkable constipation. Indeed, the number and water content of stools decreased (25.50 [n/24 h] and 29.86%) significantly (P < .05). Acute pretreatment with OPPE significantly and dose dependently accelerated the stool moistening and allowed an increase of stool weight (2.85, 3.61, 3.93 [g/24 h/rat]) as well as the frequency of defecation (47.36, 54.54, and 56.26 [n/24 h]). OPPE also significantly (P < .05) and dose dependently increased the intestinal motility (70.78%, 73.33%, and 75.01%) and gastric emptying. LOP-induced reduction (P < .05) of intestinal secretion was accompanied by a colonic and small bowel oxidative stress status and histological changes, which was attenuated by OPPE treatment. The findings of this study indicate that OPPE possesses an important role in the gastrointestinal motility regulation, and thus lend pharmacological credence to the suggested use of the natural pectin for the treatment, management, and/or control of constipation.
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