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( Rieko Kamiyama ),( Takeshi Ogura ),( Atsushi Okuda ),( Akira Miyano ),( Nobu Nishioka ),( Miyuki Imanishi ),( Wataru Takagi ),( Kazuhide Higuchi ) 대한간학회 2018 Gut and Liver Vol.12 No.4
Background/Aims: Electrohydraulic lithotripsy (EHL) under endoscopic retrograde cholangiopancreatography (ERCP) guidance can be an option to treat difficult stones. Recently, a digital, single-operator cholangioscope (SPY-DS) has become available. Peroral transluminal cholangioscopy (PTLC) using SPY-DS has also been reported. In this retrospective study, the technical feasibility and clinical effectiveness of EHL for difficult bile duct stones under ERCP guidance and under PTLC guidance was examined. Methods: In this pilot study, patients with difficult bile duct stones between July 2016 and July 2017 were retrospectively enrolled. Results: Forty-two consecutive patients underwent EHL using a SPY-DS; 34 patients underwent EHL under ERCP guidance, and the other 8 patients underwent EHL under PTLC guidance. Median procedure time was 31 minutes (range, 19 to 66 minutes). The median number of EHL sessions was 1 (range, 1 to 2), and that of ERCP sessions was also 1 (range, 1 to 3). The rate of complete stone clearance was 98% (41/42). Adverse events such as cholangitis and acute pancreatitis were seen in 14% (6/42), which could be treated conservatively. Conclusions: EHL using SPY-DS was technically feasible, not only under ERCP guidance, but also PTLC guidance. A prospective clinical study of EHL using SPY-DS is needed. (Gut Liver 2018;12:457-462)
( Atsushi Okuda ),( Takeshi Ogura ),( Miyuki Imanishi ),( Akira Miyano ),( Nobu Nishioka ),( Kazuhide Higuchi ) 대한간학회 2018 Gut and Liver Vol.12 No.4
Background/Aims: Recently, recombinant human soluble thrombomodulin (rTM) has been developed as a new drug for disseminated intravascular coagulation (DIC). This study aims to evaluate the clinical benefit of rTM in patients with sepsis-induced DIC caused by acute cholangitis who underwent biliary drainage. Methods: Patients were divided into two groups: the rTM therapy group and the non-rTM therapy group. The primary outcome was the DIC resolution rate at 7 days, and the secondary outcome was 28-day mortality rate. Results: Thirty-five patients were treated by rTM, and 36 patients were treated without rTM for DIC. The rate of resolution of DIC at day 7 was significantly higher in the rTM group than in the non-rTM group (82.9% vs 55.6%, p=0.0012). Compared with the non-rTM group, the 28-day survival rate of the r-TM group was significantly higher (rTM vs non-rTM, 91.4% vs 69.4%, p=0.014). According to multivariate analysis, non-rTM (hazard ratio [HR], 2.681) and CRP (HR, 2.370) were factors related to decreased survival. Conclusions: rTM treatment may have a positive impact on improving DIC and survival rates in patients with severe acute cholangitis. (Gut Liver 2018;12:471-477)
Features of Fatal Truck Accidents Compared with Sedans
Oikawa Shoko,Matsui Yasuhiro,Kubota Naoyuki,Aomura Shigeru,Sorimachi Kazuhiro,Imanishi Akira,Fujimura Takeshi 한국자동차공학회 2021 International journal of automotive technology Vol.22 No.4
This study clarified the features of fatal truck–pedestrian and truck–cyclist accidents by a comparison with sedans. Fatal accident data from the Japanese Institute Traffic Accident Research and Data Analysis (ITARDA) database were analyzed for the years 2012 ~ 2016. The trucks were classified into three categories: heavy-, medium-, and light-duty. All three categories had higher percentages of pedestrians as fatal collision partners as opposed to cyclists. Every truck category had significantly higher percentages of pedestrian fatalities due to daytime right turns than sedans. Heavy-duty trucks had significantly higher percentages of cyclist fatalities due to daytime and nighttime left turns than sedans. These results show that the design specifications for new sensing technology to avoid collisions with pedestrians and cyclists should differ among vehicle types. The knowledge obtained in this study will be useful to develop new technology or systems that are effective in dangerous situations between trucks and pedestrians or cyclists.
Oikawa Shoko,Matsui Yasuhiro,Kubota Naoyuki,Aomura Shigeru,Sorimachi Kazuhiro,Imanishi Akira,Fujimura Takeshi 한국자동차공학회 2023 International journal of automotive technology Vol.24 No.2
This study attempts to clarify the characteristics of light-duty truck collision accidents involving pedestrians during right-turn maneuvers by analyzing actual pedestrian accident data in Japan. Evidence differences were observed between the daytime and nighttime. The number of injured and fatal pedestrians during the day was larger than that during the night. The rate of vehicle travel velocity ≤ 10 km/h in the daytime (47.0 %) was significantly higher than that in the nighttime (39.2 %), whereas the rate of vehicle travel velocity ≤ 20 km/h in the nighttime (52.7 %) was significantly higher than that in the daytime (46.9 %). The highest rate in the daytime was presented for the age group of 13 ~ 64 years in minor injuries (54.1 %) and for those 75 years or older in serious injuries (47.5 %) and fatalities (64.3 %). For pedestrian crossing directions on the crosswalk, the pedestrian crossing from the forward left-side corner to the right-side corner exhibited the highest percentage in the daytime (39.2 %), and the opposite direction of crossing from the right-side corner to the forward left-side corner exhibited the highest percentage in the nighttime (39.6 %). The characteristics obtained in this study will contribute to the development and evaluation of advanced safety systems that are specialized for right-turning maneuvers of light-duty trucks.