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      • KCI등재

        Investigation of 180W separation by transient single withdrawal cascade using Salp Swarm optimization algorithm

        Imani Morteza,Aghaie Mahdi 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.4

        The 180W is the lightest isotope of Tungsten with small abundance ratio. It is slightly radioactive (α decay), with an extremely long half-life. Its separation is possible by non-conventional single withdrawal cascades. The 180W is used in radioisotopes production and study of metals through gamma-ray spectroscopy. In this paper, single withdrawal cascade model is developed to evaluate multicomponent separation in non-conventional transient cascades, and available experimental results are used for validation. Numerical studies for separation of 180W in a transient single withdrawal cascade are performed. Parameters affecting the separation and equilibrium time of cascade such as number of stages, cascade arrangements, feed location and flow rate for a fixed number of gas centrifuges (GC) are investigated. The Salp Swarm Algorithm (SSA) as a bio-inspired optimization algorithm is applied as a novel method to minimize the feed consumption to obtain desired concentration in the collection tank. Examining different cascade arrangements, it is observed in arrangements with more stages, the separation is further efficient. Based on the obtained results, with increasing feed flow rate, for fixed product concentration, the cascade equilibrium time decreases. Also, it is shown while the feed location is the farthest stage from the collection tank, the separation and cascade equilibrium time are well-organized. Finally, using SSA optimal parameters of the cascade is calculated, and optimal arrangement to produce 5 gr of 180W with 90% concentration in the tank, is proposed.

      • SCOPUSKCI등재

        A Survey on Asynchronous Quorum-Based Power Saving Protocols in Multi-Hop Networks

        Imani, Mehdi,Joudaki, Majid,Arabnia, Hamid R.,Mazhari, Niloofar Korea Information Processing Society 2017 Journal of information processing systems Vol.13 No.6

        Quorum-based algorithms are widely used for solving several problems in mobile ad hoc networks (MANET) and wireless sensor networks (WSN). Several quorum-based protocols are proposed for multi-hop ad hoc networks that each one has its pros and cons. Quorum-based protocol (QEC or QPS) is the first study in the asynchronous sleep scheduling protocols. At the time, most of the proposed protocols were non-adaptive ones. But nowadays, adaptive quorum-based protocols have gained increasing attention, because we need protocols which can change their quorum size adaptively with network conditions. In this paper, we first introduce the most popular quorum systems and explain quorum system properties and its performance criteria. Then, we present a comparative and comprehensive survey of the non-adaptive and adaptive quorum-based protocols which are subsequently discussed in depth. We also present the comparison of different quorum systems in terms of the expected quorum overlap size (EQOS) and active ratio. Finally, we summarize the pros and cons of current adaptive and non-adaptive quorum-based protocols.

      • Promyelocytic Leukemia (PML) Gene Mutations may not Contribute to Gastric Adenocarcinoma Development

        Imani-Saber, Zeinab,Yousefi-Razin, Ehsan,Javaheri, Mona,Mirfakhraie, Reza,Motalleb, Gholamreza,Ghafouri-Fard, Soudeh Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

        Gastric cancer is the second most common cause of cancer death worldwide. Environmental as well as genetic factors have been shown to be involved in its genesis. Among genetic factors, loss of function of a tumor suppressive gene named promyelocytic leukemia (PML) has been demonstrated in gastric cancer. In order to cast light in the mechanism by which PML protein is under-expressed in gastric cancer cells, we analyzed all exons and intron-exon boundaries of PML gene in 50 formalin-fixed paraffin-embedded tissue blocks from gastric carcinoma tumors by means of PCR-SSCP and CSGE, with direct sequencing of abnormally shifted bands. We found a novel sequence variant of unknown significance localized in intron 5 in 3 samples (c.1398+84delA). We did not detect any deleterious mutations of the PML gene. This study shows that PML mutations may not contribute to gastric adenocarcinoma development. Post-translational modifications or protein degradation might be mechanisms by which PML is not expressed in gastric tumors.

      • SCOPUSKCI등재

        Sonoanatomic Variation of Pes Anserine Bursa

        Imani, Farnad,Rahimzadeh, Poupak,Gharehdag, Farid Abolhasan,Faiz, Seyed Hamid Reza The Korean Pain Society 2013 The Korean Journal of Pain Vol.26 No.3

        Background: The pes anserine bursa lies beneath the pes anserine tendon, which is the insertional tendon of the sartorius, gracilis, and semitendinosus muscles on the medial side of the tibia, but it can lie in different sites in the medial knee. Accurate diagnosis of the position of the bursa is critical for diagnostic and therapeutic goals. The aim of this study was to evaluate sonoanatomic variations of the pes anserine bursa in the medial knee. Methods: One hundred seventy asymptomatic volunteers were enrolled in this study. Using ultrasound imaging (transverse approach, 7-13 MHz linear array probe) the sonoanatomic position of the pes anserine bursa and its relation to the pes anserine tendon were evaluated. Additionally, we evaluated the sonoanatomic variation of the saphenous nerve. Results: The position of the pes anserine bursa was between the medial collateral ligament and the pes anserine tendons in 21.2%/18.8% (males/females) of subjects; between the pes anserine tendons and the tibia in 67.1%/64.7% (m/f); and among the pes anserine tendons in 8.2%/12.9% (m/f). No significant differences in the position of the bursa existed between males and females. The saphenous nerve was found within the pes anserine tendons in 77.6%/74.1% (m/f) of subjects, but outside the pes anserine tendons in 18.8%/15.3% (m/f). Visibility of sonoanatomic structures was not related to either gender or BMI. Conclusions: Ultrasound provides very accurate information about variations in the pes anserine bursa and the saphenous nerve. This suggests that our proposed ultrasound method can be a reliable guide to facilitate approaches to the medial knee for diagnostic and therapeutic objectives.

      • In Silico Interaction and Docking Studies Indicate a New Mechanism for PML Dysfunction in Gastric Cancer and Suggest Imatinib as a Drug to Restore Function

        Imani-Saber, Zeinab,Ghafouri-Fard, Soudeh Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.12

        Gastric cancer as one of the most common cancers worldwide has various genetic and environmental risk factors including Helicobacter pylori (H.pylori) infection. Recently, loss of a tumor suppressor gene named promyelocytic leukemia (PML) has been identified in gastric cancer. However, no mutation has been found in this gene in gastric cancer samples. Cag A H.pylori protein has been shown to exert post transcriptional regulation of some tumor suppressor genes. In order to assess such a mechanism for PML degradation, we performed in silico analyses to establish any interaction between PML and Cag A proteins. In silico interaction and docking studies showed that these two proteins may have stable interactions. In addition, we showed that imatinib kinase inhibitor can restore PML function by inhibition of casein kinase 2.

      • Temperature-Controllable Hydrogels in Double-Walled Microtube Structure Prepared by Using a Triple Channel Microfluidic System

        Imani, Kusuma Betha Cahaya,Kim, Dongwan,Kim, Dowan,Yoon, Jinhwan American Chemical Society 2018 Langmuir Vol.34 No.38

        <P>Hydrogels in the shape of double-walled microtubes possess great potential for development into artificial human blood vessels. In this work, we have prepared temperature-responsive tubular hydrogels with selectively controllable wall diameters, by using alginate templated photopolymerization in a triple channel microfluidic device. These tubular hydrogels mimic human blood vessels because of the separate thermally active inner and passive outer walls. The different behavior of each wall leads to the expansion of the hollow center volume with increasing temperature. This temperature-based control of the hollow center volume cannot be achieved in the case of conventional hydrogel microtubes. Furthermore, through this method, the hydrogels can be modified to achieve a controllable outer diameter while maintaining the hollow center dimensions simply by changing the position of the hydrogel walls. The ability to change the layer properties of the developed system indicates that the preparation of hydrogels with various monomers is possible.</P> [FIG OMISSION]</BR>

      • Promyelocytic Leukemia Gene Functions and Roles in Tumorigenesis

        Imani-Saber, Zeinab,Ghafouri-Fard, Soudeh Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        The promyelocytic leukemia (PML) gene is a gene known to be a tumor suppressor, although recent data suggest that it has a dual function in tumorigenesis. It was initially discovered in acute promyelocytic leukemia (APL) in which a t(15; 17) chromosomal translocation fused it to the retinoic acid receptor alpha ($RAR{\alpha}$). It has been shown to be involved in various types of cancer. It has at least 6 nuclear isoforms and a cytoplasmic type with different characteristics. Its multiple functions in growth inhibition, apoptosis induction, replicative senescence, inhibition of oncogenic transformation, and suppression of migration and angiogenesis have made it a therapeutic target for cancer therapy. However, its dual role in the process of tumorigenesis has made this field challenging. In this review, we discuss PML structure, functions and expression in tumors.

      • KCI등재

        The effect of Tetranychus turkestani and Eutetranychus orientalis (Acari: Tetranychidae) on the development and reproduction of Stethorus gilvifrons (Coleoptera: Coccinellidae)

        Z. Imani,F. Sohrabi,P. Shishehbor 한국응용곤충학회 2009 Journal of Asia-Pacific Entomology Vol.12 No.4

        Stethorus gilvifrons Mulsant, native to the Mediterranean region, is often observed feeding on Tetranychus turkestani Ugarov & Nycolsky and Eutetranychus orientalis Klein on different host crops. Fecundity of S. gilvifrons on T. turkestani and E. orientalis was evaluated by placing newly emerged pairs on leaf discs infested with different developmental stages of T. turkestani or E. orientalis. They were maintained at 30 °C and changed daily until death of the female. Adult female mean longevity was 58 days on T. turkestani and 45 days on E. orientalis. Mean fecundity was 175 eggs per female on T. turkestani and 318 eggs per female on E. orientalis. No significant differences were detected in the duration of life stages between T. turkestani and E. orientalis. Mean preimaginal mortality was 20% on T. turkestani and 24% on E. orientalis, with no statistical differences. Mean generation time (T) was 26.76 and 22.83 days on T. turkestani and E. orientalis, respectively. Net reproductive rate (Ro) was significantly greater on E. orientalis (154.08) than on T. turkestani (97.6), but the estimate of intrinsic rate of increase (rm) was not statistically different (0.221 and 0.171, respectively). Our results suggest that both T. turkestani and E. orientalis are essential prey for S. gilvifrons development and reproduction and that E. orientalis is slightly more suitable than T. turkestani. Stethorus gilvifrons Mulsant, native to the Mediterranean region, is often observed feeding on Tetranychus turkestani Ugarov & Nycolsky and Eutetranychus orientalis Klein on different host crops. Fecundity of S. gilvifrons on T. turkestani and E. orientalis was evaluated by placing newly emerged pairs on leaf discs infested with different developmental stages of T. turkestani or E. orientalis. They were maintained at 30 °C and changed daily until death of the female. Adult female mean longevity was 58 days on T. turkestani and 45 days on E. orientalis. Mean fecundity was 175 eggs per female on T. turkestani and 318 eggs per female on E. orientalis. No significant differences were detected in the duration of life stages between T. turkestani and E. orientalis. Mean preimaginal mortality was 20% on T. turkestani and 24% on E. orientalis, with no statistical differences. Mean generation time (T) was 26.76 and 22.83 days on T. turkestani and E. orientalis, respectively. Net reproductive rate (Ro) was significantly greater on E. orientalis (154.08) than on T. turkestani (97.6), but the estimate of intrinsic rate of increase (rm) was not statistically different (0.221 and 0.171, respectively). Our results suggest that both T. turkestani and E. orientalis are essential prey for S. gilvifrons development and reproduction and that E. orientalis is slightly more suitable than T. turkestani.

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