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이상암,Im Kayeong,Yang Ha-rin 대한의학회 2023 Journal of Korean medical science Vol.38 No.8
Background: Little is known regarding the effects of continuous positive airway pressure (CPAP) on sleep misperception in obstructive sleep apnea (OSA). Methods: Sleep state perception was measured by subtracting the objective total sleep time from the subjective sleep duration. Sleep underestimation and overestimation were defined as ± 60 minutes sleep perception. Insomnia and depressive symptoms were assessed using questionnaires. Finally, nonparametric statistical analyses were performed. Results: Of the 339 patients with OSA included in the study, 90 (26.5%) and 45 (13.3%) showed sleep underestimation and overestimation, respectively. Overall, a significant underestimation of sleep was noted during CPAP titration comparing to a diagnostic PSG (P < 0.001). OSA patients with insomnia or depressive symptoms did not show any changes in sleep perception between diagnostic and CPAP titration studies, whereas those without insomnia or depressed mood showed significantly underestimated sleep duration during CPAP titration. Patients with OSA and either underestimated or overestimated misperception showed perceptual improvements during CPAP titration regardless of the presence of insomnia or depressive symptoms. However, of 204 patients with normal sleep perception, 138 (67.6%) and 10 (4.9%) had underestimation and overestimation of sleep during CPAP titration. Conclusion: CPAP titration may improve sleep perception with moderate to severe OSA who have sleep misperception. However, CPAP titration may result in sleep misperception especially underestimation of sleep in those who have normal sleep perception.
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권겸일,Mina Lee,Hyunjin Ju,Kayeong Im 대한파킨슨병및이상운동질환학회 2020 Journal Of Movement Disorders Vol.13 No.2
ObjectiveaaWe aimed to identify risk factors for falls in patients with de novo Parkinson’s disease (PD). MethodsaaForty-six patients with de novo PD were retrospectively included in the study. We assessed details on the patients’ motorsymptoms as well as non-motor symptoms using several representative scales for global cognition, depression, fatigue, anddysautonomia. Fallers and non-fallers were identified according to their history of falls during the preceding year. ResultsaaTwenty-two patients (45.8%) with de novo PD had a history of falls. Compared with the non-faller group, the fallergroup exhibited higher scores for postural instability/gait difficulty (PIGD), anxiety, fatigue, total dysautonomia, gastrointestinaldysfunction, and thermoregulatory dysfunction. Moreover, logistic regression analysis showed that falling was positively correlatedwith anxiety and gastrointestinal symptoms but negatively associated with the tremor scores. ConclusionaaOur findings suggest that falling in patients with de novo PD is significantly associated with PIGD/non-tremorsymptoms, anxiety, and gastrointestinal dysfunction.
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