http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
한심희,김찬수,장석성,이현주,탁우식 한국농림기상학회 2004 한국농림기상학회지 Vol.6 No.3
This study was conducted to examine the changes in the seed physical characters and germinative properties of three tree species at three different storage times in order to determine the most suitable storage time and condition. Seed physical characters and germinative properties were examined from seeds of Fraxinus rhynchophylla, Zanthoxylum schinifolium and Staphylea bumalda that were stored at -18C for 1, 3 and 10 years, and the growth performance and physiological characters of their seedlings were analyzed. Seed physical characters and germinative properties showed significant differences between three storage times as well as three tree species. Seed moisture content of F. rhynchophylla and S. bumalda and seed fresh weight of Z. schinifolium decreased with increase of storage time. Storage time represented negative correlation with moisture content and fresh weight (r = -0.822, p < 0.01). Seed percent germination of Z. schinifolium and S. bumalda stored for 3 and 10 years decreased less than 15% and 10.7% respectively. Mean germination times for seed of F. rhynchophylla, Z. schinifolium and S. bumalda were delayed 11.9, 5.7 and 9.7 days after a storage time of 10 years, respectively. However the growth and viability of seedlings didn't show a special pattern for storage time and tree species.
Hidden Markov Chain 모형과 이변량 코플라함수를 이용한 가뭄빈도분석
전시영,김용탁,권현한,Chun, Si-Young,Kim, Yong-Tak,Kwon, Hyun-Han 한국수자원학회 2015 한국수자원학회논문집 Vol.48 No.12
본 연구에서는 가뭄의 특성분석에 유리하며, 확률론적 접근이 가능한 은닉 마코프 모델(HMM) 기반의 가뭄 분석 기법을 적용하였다. HMM 기반의 가뭄의 심도뿐만 아니라 지속시간을 동시에 평가할 수 있도록 코플라 함수 기반의 이변량 가뭄빈도해석 기법을 도입하여 우리나라의 2015년 가뭄 빈도를 평가하였다. 가뭄빈도분석 결과 최근 40년 자료를 기준으로 영동지방에 비해 영서지방이 전체적으로 가뭄이 발생할 경우 가뭄의 심도가 큰 것으로 평가되었다. 심한가뭄의 발생 비율의 경우에 철원의 경우 10%를 상회하는 등 임진강 유역에서 상대적으로 심한가뭄의 발생비율이 크다는 것을 확인할 수 있었다. 한강유역 일부지점에서는 2014/2015년의 가뭄 지속기간 및 심도의 결합재현기간이 1,000년이 넘는 가뭄이 발생하고 있는 것으로 평가되었다. 특히 북한강 및 임진강 유역에 심한 가뭄이 발생하고 있으며 전반적으로 100년 이상의 기왕최대가뭄을 나타내고 있는 것으로 판단되었다. This study applied a probabilistic-based hidden Markov model (HMM) to better characterize drought patterns. In addition, a copula-based bivariate drought frequency analysis was employed to further investigate return periods of the current drought condition in year 2015. The obtained results revealed that western Kangwon area was generally more vulnerable to drought risk than eastern Kangwon area using the 40-year data. Imjin-river watershed including Cheorwon area was the most vulnerable area in terms of severe drought events. Four stations in Han-river watershed showed a joint return period exceeding 1,000 years associated with the drought duration and severity in 2014-2015. Especially, current drought status in Northern Han-river and Imjin-river watershed is most severe drought exceeding 100-year return period.
Su-Hyun Han,Choon-Tak Kwon,Yasuhito Sakuraba,Nam-Chon Paek 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07
In field conditions, the zebra2 (z2) mutant in rice (Oryza sativa) produces leaves with transverse pale-green/yellow stripes. It was recently reported that ZEBRA2 encodes carotenoid isomerase (CRTISO) and that low levels of lutein, an essential carotenoid for non-photochemical quenching, cause leaf variegation in z2 mutants. However, we found that the z2 mutant phenotype was completely suppressed by growth under continuous light (CL; permissive) conditions, with concentrations of chlorophyll, carotenoids and chloroplast proteins at normal levels in z2 mutants under CL. In addition, three types of reactive oxygen species (ROS; superoxide [O2-], hydrogen peroxide [H2O2], and singlet oxygen [1O2]) accumulated to high levels in z2 mutants grown under short-day conditions (SD; alternate 10-h light/14-h dark; restrictive), but do not accumulate under CL conditions. However, the levels of lutein and zeaxanthin in z2 leaves were much lower than normal in both permissive CL and restrictive SD growth conditions, indicating that deficiency of these two carotenoids is not responsible for the leaf variegation phenotype. We found that the CRTISO substrate tetra-cis-lycopene accumulated during the dark periods under SD, but not under CL conditions. Its accumulation was also positively correlated with 1O2 levels generated during the light period, which consequently altered the expression of 1O2-responsive and cell death-related genes in the variegated z2 leaves. Taking these results together, we propose that the z2 leaf variegation can be largely attributed to photoperiodic accumulation of tetra-cis-lycopene and generation of excessive 1O2 under natural day-night conditions.
Lee, Mi Jung,Han, Seung Hyeok,Lee, Jung Eun,Choi, Hoon Young,Yoon, Chang-Yun,Kim, Eun Jin,Han, Jae Hyun,Han, Ji Suk,Oh, Hyung Jung,Park, Jung Tak,Kang, Shin-Wook,Yoo, Tae-Hyun Wolters Kluwer Health 2014 Medicine Vol.93 No.11
<P><B>Abstract</B></P><P>Endothelial dysfunction is implicated in increased cardiovascular risk in nondialyzed population. However, the prognostic impact of endothelial dysfunction on cardiovascular outcome has not been investigated in peritoneal dialysis (PD) patients.</P><P>We prospectively determined endothelial function by brachial artery endothelium-dependent vasodilation (flow-mediated dilation [FMD]) in 143 nondiabetic PD patients and 32 controls. Primary outcome was a major adverse cardiac and cerebrovascular event (MACCE).</P><P>Brachial FMD was significantly lower in PD patients than in controls (2.9% [1.3–4.7] vs 6.2% [5.4–8.3], <I>P</I> < 0.001). During a mean follow-up of 42 months, primary outcome was observed in 25 patients (17.5%). When patients were dichotomized by the median value of FMD (2.9%), incidence rates of MACCEs were significantly higher in the group with lower FMD compared with higher FMD (7.2 vs 3.0/100 person-years, <I>P</I> = 0.03). In multivariate Cox analysis, low FMD (≤2.9%) was a significant independent predictor of MACCEs (hazard ratio = 2.73, 95% confidence interval = 1.03–7.22, <I>P</I> = 0.04). Furthermore, multivariate fractional polynomial analysis showed that the risk of MACCE decreased steadily with higher FMD values.</P><P>Impaired brachial FMD was a significant independent predictor of MACCEs in PD patients. Estimating endothelial dysfunction by brachial FMD could be useful for stratifying cardiovascular risk in these patients.</P>
Oh, Hyung Jung,Nam, Bo Young,Lee, Mi Jung,Kim, Chan Ho,Koo, Hyang Mo,Doh, Fa Mee,Han, Jae Hyun,Kim, Eun Jin,Han, Ji Suk,Park, Jung Tak,Yoo, Tae-Hyun,Kang, Shin-Wook,Han, Dae-Suk,Han, Seung Hyeok International Society for Peritoneal Dialysis 2015 Peritoneal dialysis international Vol.35 No.1
<P>♦ <I>Introduction:</I> It has been reported that klotho deficiency is associated with oxidative stress and inflammation in experimental kidney disease models. Patients with endstage renal disease (ESRD) are particularly characterized by increased oxidative stress and inflammation. However, little is known about the relationship between these features and klotho in patients with ESRD.</P><P>♦ <I>Methods:</I> We conducted a single-center, cross-sectional study of 78 patients receiving peritoneal dialysis (PD). Serum concentrations of klotho, high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), and 8-isoprostane were measured by enzyme-linked immunosorbent assay. To define factors independently associated with klotho, we determined Spearman’s correlation coefficients for between co-variates and conducted multiple linear regression analyses.</P><P>♦ <I>Results:</I> Patients were classified by median concentration of klotho. In patients with klotho levels > 329.6 pg/mL, serum 8-isoprostane and IL-6 levels were significantly higher than in those with klotho levels < 329.6 pg/mL. In correlation analyses, log 8-isoprostane (γ = –0.310, <I>p</I> = 0.006) and log IL-6 (γ = –0.343, <I>p</I> = 0.002) were inversely correlated with log klotho. After adjustment for age, gender, mean arterial pressure, log intact parathyroid hormone, and log IL-6, log 8-isoprostane was independently associated with log klotho (β = –0.158, <I>p</I> = 0.040). However, the significant relationship between klotho and IL-6 was not seen in an adjusted model.</P><P>♦ <I>Conclusions:</I> This study showed that circulating klotho levels were significantly associated with 8-isoprostane levels in patients undergoing PD, suggesting a potential link between klotho deficiency and enhanced oxidative stress in ESRD patients.</P>
PGC-1<i>α</i> Protects from Notch-Induced Kidney Fibrosis Development
Han, Seung Hyeok,Wu, Mei-yan,Nam, Bo Young,Park, Jung Tak,Yoo, Tae-Hyun,Kang, Shin-Wook,Park, Jihwan,Chinga, Frank,Li, Szu-Yuan,Susztak, Katalin American Society of Nephrology 2017 Journal of the American Society of Nephrology Vol.28 No.11
Hyun-Min Tak,Changyong Choe,Young-Woo Cho,Jaehee Han,Dawon Kang 한국동물번식학회 2012 Reproductive & Developmental Biology(Supplement) Vol.36 No.2s
Microtubule-associated protein 1B (MAP1B), a member of MAP1 family, plays a key role in the brain development. MAP1B binds to many kinds of proteins directly or indirectly. In our previous studies, MAP1B and glyceraldehydes 3-phosphate dehydrogenase (GAPDH) were down-regulated in bovine follicular cystic follicles (FCF). This study was performed to examine interaction between MAP1B and GAPDH in bovine follicles using immunoprecipitation (IP) with western blot analysis and immunohistochemisty. MAP1B and GAPDH mRNA expression levels were down-regulated in bovine FCFs. Consistent with the semi-quantitative PCR data, their protein expressions were also down-regulated in FCFs. IP data showed that MAP1B bound to GAPDH in normal follicles, but their binding was absent in FCFs, suggesting that these data might be resulted from a low level of MAP1B and/or GAPDH expression. These results suggest that GAPDH does not as always function as a loading control in bovine follicles.
Han, Ji-Youn,Lee, Soo-Hyun,Yoo, Nam Jin,Hyung, Lee Suk,Moon, Yoon Joo,Yun, Tak,Kim, Heung Tae,Lee, Jin Soo American Association for Cancer Research 2011 Clinical Cancer research Vol.17 No.6
<P>To evaluate the efficacy and safety of gefitinib plus simvastatin (GS) versus gefitinib alone (G) in previously treated patients with advanced non-small cell lung cancer (NSCLC).</P>
Han, Yoon-Tak,Oh, Joon-Seok,Cha, Jae-Hun,An, Jae-Yun,Hyun, Seung-Yoon,Lee, Jong-Kwan,Seo, In-Yong,Kim, Jae-Eon The Korean Institute of Electrical Engineers 2017 Journal of Electrical Engineering & Technology Vol.12 No.6
To resolve overload in a distribution system, a distribution system operator (DSO) often performs a load transfer using normally open tie points and switches in the distribution line. During this process, the distribution system is momentarily operated in closed-loop operation. A closed-loop current in the distribution system can cause a power failure due to excess breaking current in the circuit breakers and reclosers. Therefore, it is necessary to calculate the closed-loop current exactly. However, if there are a large number of distributed generation (DG) systems in the distribution system, such as energy storage systems (ESS), they might obstruct the closed-loop operation based on bidirectional power flow. For quick and precise operation of a closed-loop system, the ESS has to regulate the power generation while satisfying closed-loop operation in the worst cases. We propose a strategy for balanced power regulation of an ESS. Simulations were carried out using PSCAD/EMTDC, and the results were compared with calculation results.