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응결시간 조절형 아질산계 방청제 개발과 전기화학적 방식성능 평가에 관한 실험적 연구
문병철(Moon Byung-Chul),유조형(Yoo Jo-Hyeong),이한승(Lee Han-Seung),이문성(Lee Moon-Sung) 대한건축학회 2009 大韓建築學會論文集 : 構造系 Vol.25 No.1
The purpose of this study is developing a new corrosion inhibitor which improves durability of concrete. It is understood that there are various methods to protect the corrosion of reinforcing steels in concrete such as the nitrous acid lithium, the nitrous acid calcium and so on. When we use the corrosion inhibitor in large quantities, there are accelerates setting time and affect to durability of concrete problem. The nitrous acid lithium has a good effect on delays setting time. However, it is more expensive the nitrous acid calcium, so the nitrous acid calcium has used more than the nitrous acid lithium. When the nitrous acid calcium is in large quantity, there is an accelerates setting time problem. From the results of the experiments, it was confirmed that the lithium, calcium nitrite corrosion inhibitor and new corrosion inhibitor over dossage 0.6 (NO₂-/Cl?) molar ratio is very effective in protecting reinforce ment from corrosion in mortar in which chloride ions have contained.
Moon, Hyeong Cheol,Won, So Yoon,Kim, Eung Gook,Kim, Hyong Kyu,Cho, Chul Bum,Park, Young Seok Elsevier/North-Holland 2018 Neuroscience letters Vol.662 No.-
<P><B>Abstract</B></P> <P><B>Objective</B></P> <P>Neuromodulation of the globus pallidus internus(GPi) alleviates Parkinson’s disease symptoms. The primate GPi is homologous to the rat entopeduncular nucleus (EP). The aim of the present study was to determine if optogenetic modulation of the EP could alter parkinsonian behavior or thalamic discharge in a hemiparkinson rat model.</P> <P><B>Methods</B></P> <P>We injected an adeno-associated virus type-2 expressing α-synuclein (AAV2-α-syn) into the substantia nigra pars compacta (SNc) of the right hemisphere and confirmed parkinsonian behavior using an amphetamine-induced rotation test. Then we injected activated or inhibited neurons, using the channelrhodopsin2 (ChR2)/halorhodopsin (NpHR) system in the EP of the hemiparkinson rat model and examined downstream effects <I>in vivo</I>. We assessed alterations in parkinsonian behaviors using the stepping and cylinder tests before, during, and after optogenetic stimulation.</P> <P><B>Results</B></P> <P>Importantly, optogenetic inhibition of the EP improved parkinsonian motor behaviors. When we monitored thalamic neuronal activity following optogenetic neuromodulation <I>in vivo</I>, and we observed alterations in thalamic discharge The thalamic neuronal activity is increased for optogenetic inhibition stimulation, whereas decreased for optogenetic activation stimulation.</P> <P><B>Conclusions</B></P> <P>Taken together, our data demonstrate that optical neuromodulation of the EP can successfully control contralateral forelimb movement and thalamic discharge in an AAV2-α-synuclein-induced hemiparkinson rat model.</P> <P><B>Highlights</B></P> <P> <UL> <LI> To test whether optogenetic modulation of the entopeduncular nucleus(EP) could alter parkinsonian behavior or thalamic discharge in a hemiparkinson rat model. </LI> <LI> The globus pallidus internus (GPi) in primates is homologous to the entopeduncular nucleus (EP) in rats. </LI> <LI> The author compared parkinson behavior and recorded <I>in vivo</I> neuronal activity between pre- and post-stimulation in hemiparkinson rat model. </LI> <LI> Optical neuromodulation of the EP can be used to successfully control contralateral forelimb movement and thalamic discharge to alleviate symptoms in an AAV2-α-syn-induced hemiparkinson rat model. </LI> </UL> </P>
Moon, Hyeong Cheol,Park, Chan-A,Jeon, Yeong-Jae,You, Soon Tae,Baek, Hyun Man,Lee, Youn Joo,Cho, Chul Beom,Cheong, Chae Joon,Park, Young Seok Elsevier 2018 Magnetic resonance imaging Vol.51 No.-
<P><B>Abstract</B></P> <P>The cingulate cortex (CC) is a brain region that plays a key role in pain processing, but CC abnormalities are not unclear in patients with trigeminal neuralgia (TN). The purpose of this study was to determine the central causal mechanisms of TN and the surrounding brain structure in healthy controls and patients with TN using 7 Tesla (T) magnetic resonance imaging (MRI). Whole-brain parcellation in gray matter volume and thickness was assessed in 15 patients with TN and 16 healthy controls matched for sex, age, and regional variability using T1-weighted imaging. Regions of interest (ROIs) were measured in rostral anterior CC (rACC), caudal anterior CC (cACC) and posterior CC (PCC). We also investigated associations between gray matter volume or thickness and clinical symptoms, such as pain duration, Barrow Neurologic Institute (BNI) scores, offender vessel, and medications, in patients with TN. The cACC and PCC exhibited gray matter atrophy and reduced thickness between the TN and control groups. However, the rACC did not. Cortical volumes were negatively correlated with pain duration in transverse and inferior temporal areas, and thickness was also negatively correlated with pain duration in superior frontal and parietal areas. The cACC and PCC gray matter atrophy occurred in the patients with TN, and pain duration was associated with frontal, parietal, and temporal cortical regions. These results suggest that the cACC, PCC but not the rACC are associated with central pain mechanisms in TN.</P>
Park, Hyeong-Cheol,Kim, Man-Lyang,Kang, Yun-Hwan,Jeon, Joo-Mi,Yoo, Jae-Hyuk,Kim, Min-Chul,Park, Chan-Young,Jeong, Jae-Cheol,Moon, Byeong-Cheol,Lee, Ju-Huck,Yoon, Hae-Won,Lee, Sung-Ho,Chung, Woo-Sik,Li Plant molecular biology and biotechnology research 2004 Plant molecular biology and biotechnology research Vol.2004 No.-
The Ca^(2+)-binding protein calmodulin mediates cellular Ca^(2+) signals in response to a wide array of stimuli in higher eukaryotes. Plants express numerous CaM isoforms. Transcription of one soybean (Glycine max) CaM isoform, SCaM-4, is dramatically induced within 30 min of pathogen or NaCl stresses. To characterize the cis-acting element(s) of this gene, we isolated an approximately 2-kb promoter sequence of the gene. Deletion analysis of the promoter revealed that a 130-bp region located between nucleotide positions -858 and -728 is required for the stressors to induce expression of SCaM-4. A hexameric DNA sequence within this region, GAAAAA (GT-1 cis-element), was identified as a core cis-acting element for the induction of the SCaM-4 gene. The GT-1 cis-element interacts with an Arabidopsis GT-1-like transcription factor, AtGT-3b, in vitro and in a yeast selection system. Transcription of AtGT-3b is also rapidly induced within 30 min after pathogen and NaCl treatment. These results suggest that an interaction between? GT-1 cis-element and a GT-1-like transcription factor plays a role in pathogen- and salt-induced SCaM-4 gene expression in both soybean and Arabidopsis.